标题
Role of HOXA9 in leukemia: dysregulation, cofactors and essential targets
作者
关键词
-
出版物
ONCOGENE
Volume 35, Issue 9, Pages 1090-1098
出版商
Springer Nature
发表日期
2015-06-01
DOI
10.1038/onc.2015.174
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Three-dimensional genome architecture: players and mechanisms
- (2015) Ana Pombo et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- HoxA9 regulated Bcl-2 expression mediates survival of myeloid progenitors and the severity of HoxA9-dependent leukemia
- (2015) Gabriela Brumatti et al. Oncotarget
- TALE Factors Poise Promoters for Activation by Hox Proteins
- (2014) Seong-Kyu Choe et al. DEVELOPMENTAL CELL
- The methyltransferase G9a regulates HoxA9-dependent transcription in AML
- (2014) B. Lehnertz et al. GENES & DEVELOPMENT
- Insulin-like growth factor 1 is a direct HOXA9 target important for hematopoietic transformation
- (2014) J Steger et al. LEUKEMIA
- C/EBPα is an essential collaborator in Hoxa9/Meis1-mediated leukemogenesis
- (2014) Cailin Collins et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- p15Ink4b Functions in determining hematopoietic cell fates: Implications for its role as a tumor suppressor
- (2013) Linda Wolff et al. BLOOD CELLS MOLECULES AND DISEASES
- The long non-coding RNA HOTAIR indicates a poor prognosis and promotes metastasis in non-small cell lung cancer
- (2013) Xiang-hua Liu et al. BMC CANCER
- Long non-coding RNA HOTAIR is an independent prognostic marker of metastasis in estrogen receptor-positive primary breast cancer
- (2013) Kristina P. Sørensen et al. BREAST CANCER RESEARCH AND TREATMENT
- Long non-coding RNAs: A new frontier in the study of human diseases
- (2013) Xuefei Shi et al. CANCER LETTERS
- HOTAIR, a prognostic factor in esophageal squamous cell carcinoma, inhibits WIF-1 expression and activates Wnt pathway
- (2013) Xiao-Song Ge et al. CANCER SCIENCE
- Biochemistry of the tale transcription factors PREP, MEIS, and PBX in vertebrates
- (2013) E. Longobardi et al. DEVELOPMENTAL DYNAMICS
- Tracking context-specific transcription factors regulating hox activity
- (2013) Samir Merabet et al. DEVELOPMENTAL DYNAMICS
- Hox regulation of transcription: More complex(es)
- (2013) Franck Ladam et al. DEVELOPMENTAL DYNAMICS
- Non-transcriptional interactions of Hox proteins: Inventory, facts, and future directions
- (2013) René Rezsohazy DEVELOPMENTAL DYNAMICS
- Hoxa9 collaborates with E2A-PBX1 in mouse B cell leukemia in association with Flt3 activation and decrease of B cell gene expression
- (2013) Mona Hassawi et al. DEVELOPMENTAL DYNAMICS
- “Self-regulation,” a new facet ofHoxgenes' function
- (2013) Rushikesh Sheth et al. DEVELOPMENTAL DYNAMICS
- Cell-type specificcis-regulatory networks
- (2013) Maria Polychronidou et al. FLY
- Hoxc Gene Collinear Expression and Epigenetic Modifications Established during Embryogenesis Are Maintained until after Birth
- (2013) Hyehyun Min et al. International Journal of Biological Sciences
- Bromodomain-PHD finger protein 1 is critical for leukemogenesis associated with MOZ–TIF2 fusion
- (2013) Haruko Shima et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Myelodysplastic syndromes are induced by histone methylation–altering ASXL1 mutations
- (2013) Daichi Inoue et al. JOURNAL OF CLINICAL INVESTIGATION
- Induction of long intergenic non-coding RNA HOTAIR in lung cancer cells by type I collagen
- (2013) Yan Zhuang et al. Journal of Hematology & Oncology
- Epigenetic dysregulation of leukaemic HOX code inMLL-rearranged leukaemia mouse model
- (2013) Ray Kit Ng et al. JOURNAL OF PATHOLOGY
- NUP98/JARID1A is a novel recurrent abnormality in pediatric acute megakaryoblastic leukemia with a distinct HOX gene expression pattern
- (2013) J D E de Rooij et al. LEUKEMIA
- Multiple mechanisms deregulate EZH2 and histone H3 lysine 27 epigenetic changes in myeloid malignancies
- (2013) S N Khan et al. LEUKEMIA
- The fusion partner specifies the oncogenic potential of NUP98 fusion proteins
- (2013) Jesslyn Saw et al. LEUKEMIA RESEARCH
- HOTAIR, a cell cycle–associated long noncoding RNA and a strong predictor of survival, is preferentially expressed in classical and mesenchymal glioma
- (2013) Jun-Xia Zhang et al. NEURO-ONCOLOGY
- HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias
- (2013) F J Calero-Nieto et al. ONCOGENE
- Hoxa9 Transduction Induces Hematopoietic Stem and Progenitor Cell Activity through Direct Down-Regulation of Geminin Protein
- (2013) Yoshinori Ohno et al. PLoS One
- Contribution of Distinct Homeodomain DNA Binding Specificities to Drosophila Embryonic Mesodermal Cell-Specific Gene Expression Programs
- (2013) Brian W. Busser et al. PLoS One
- The Homeodomain Transcription Factor Hoxa2 Interacts with and Promotes the Proteasomal Degradation of the E3 Ubiquitin Protein Ligase RCHY1
- (2013) Isabelle Bergiers et al. PLoS One
- Analysis of the DNA-Binding Profile and Function of TALE Homeoproteins Reveals Their Specialization and Specific Interactions with Hox Genes/Proteins
- (2013) Dmitry Penkov et al. Cell Reports
- Antagonism Versus Cooperativity with TALE Cofactors at the Base of the Functional Diversification of Hox Protein Function
- (2013) María Luisa Rivas et al. PLoS Genetics
- Distinct Molecular Strategies for Hox-Mediated Limb Suppression in Drosophila: From Cooperativity to Dispensability/Antagonism in TALE Partnership
- (2013) Nagraj Sambrani et al. PLoS Genetics
- Quantitative multiplex quantum dot in-situ hybridisation based gene expression profiling in tissue microarrays identifies prognostic genes in acute myeloid leukaemia
- (2012) Eleni Tholouli et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML
- (2012) Z. Li et al. BLOOD
- Beyond Hox: the role of ParaHox genes in normal and malignant hematopoiesis
- (2012) V. P. S. Rawat et al. BLOOD
- PBX3 is an important cofactor of HOXA9 in leukemogenesis
- (2012) Z. Li et al. BLOOD
- The homeodomain region controls the phenotype of HOX-induced murine leukemia
- (2012) C. Breitinger et al. BLOOD
- Protein interactions of the transcription factor Hoxa1
- (2012) Barbara Lambert et al. BMC DEVELOPMENTAL BIOLOGY
- Selective treatment of mixed-lineage leukemia leukemic stem cells through targeting glycogen synthase kinase 3 and the canonical Wnt/β-catenin pathway
- (2012) Tsz K. Fung et al. CURRENT OPINION IN HEMATOLOGY
- Regulatory role for a conserved motif adjacent to the homeodomain of Hox10 proteins
- (2012) I. Guerreiro et al. DEVELOPMENT
- Dimer formation via the homeodomain is required for function and specificity of Sex combs reduced in Drosophila
- (2012) Dimitrios K. Papadopoulos et al. DEVELOPMENTAL BIOLOGY
- Hox transcription factors influence motoneuron identity through the integrated actions of both homeodomain and non-homeodomain regions
- (2012) Mala Misra et al. DEVELOPMENTAL DYNAMICS
- Thecis-regulatory code of Hox function inDrosophila
- (2012) Sebastian Sorge et al. EMBO JOURNAL
- Gene expression profiling and candidate gene resequencing identifies pathways and mutations important for malignant transformation caused by leukemogenic fusion genes
- (2012) Rachel L. Novak et al. EXPERIMENTAL HEMATOLOGY
- HOX genes regulate Rac1 activity in hematopoietic cells through control of Vav2 expression
- (2012) C Breitinger et al. LEUKEMIA
- Polycomb-group proteins in hematopoietic stem cell regulation and hematopoietic neoplasms
- (2012) V Radulović et al. LEUKEMIA
- The role of HOX genes in normal hematopoiesis and acute leukemia
- (2012) R A Alharbi et al. LEUKEMIA
- HOXA9 Methylation by PRMT5 Is Essential for Endothelial Cell Expression of Leukocyte Adhesion Molecules
- (2012) S. Bandyopadhyay et al. MOLECULAR AND CELLULAR BIOLOGY
- Scmh1 Has E3 Ubiquitin Ligase Activity for Geminin and Histone H2A and Regulates Geminin Stability Directly or Indirectly via Transcriptional Repression of Hoxa9 and Hoxb4
- (2012) S. Yasunaga et al. MOLECULAR AND CELLULAR BIOLOGY
- Upregulation of the long non-coding rna hotair promotes esophageal squamous cell carcinoma metastasis and poor prognosis
- (2012) Fang-Jun Chen et al. MOLECULAR CARCINOGENESIS
- ADP Ribosylation by PARP-1 Suppresses HOXB7 Transcriptional Activity
- (2012) Xinyan Wu et al. PLoS One
- Structural basis for homeodomain recognition by the cell-cycle regulator Geminin
- (2012) B. Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Distinct regulation of c-myb gene expression by HoxA9, Meis1 and Pbx proteins in normal hematopoietic progenitors and transformed myeloid cells
- (2012) E Dassé et al. Blood Cancer Journal
- The Structure of the Nuclear Pore Complex
- (2011) André Hoelz et al. Annual Review of Biochemistry
- The Pathogenesis of Mixed-Lineage Leukemia
- (2011) Andrew G. Muntean et al. Annual Review of Pathology-Mechanisms of Disease
- Identification and characterization of Hoxa9 binding sites in hematopoietic cells
- (2011) Y. Huang et al. BLOOD
- NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights
- (2011) S. M. Gough et al. BLOOD
- NUP98/NSD1 characterizes a novel poor prognostic group in acute myeloid leukemia with a distinct HOX gene expression pattern
- (2011) I. H. I. M. Hollink et al. BLOOD
- Long Noncoding RNA HOTAIR Regulates Polycomb-Dependent Chromatin Modification and Is Associated with Poor Prognosis in Colorectal Cancers
- (2011) R. Kogo et al. CANCER RESEARCH
- Cofactor Binding Evokes Latent Differences in DNA Binding Specificity between Hox Proteins
- (2011) Matthew Slattery et al. CELL
- Polycomb-Dependent Regulatory Contacts between Distant Hox Loci in Drosophila
- (2011) Frédéric Bantignies et al. CELL
- Functional Crosstalk between Bmi1 and MLL/Hoxa9 Axis in Establishment of Normal Hematopoietic and Leukemic Stem Cells
- (2011) Lan-Lan Smith et al. Cell Stem Cell
- The histone deacetylase inhibitor entinostat (SNDX-275) induces apoptosis in Hodgkin lymphoma cells and synergizes with Bcl-2 family inhibitors
- (2011) Ádám Jóna et al. EXPERIMENTAL HEMATOLOGY
- A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression
- (2011) Kevin C. Wang et al. NATURE
- Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice
- (2011) George S Vassiliou et al. NATURE GENETICS
- Genome-Wide Analysis of the Binding of the Hox Protein Ultrabithorax and the Hox Cofactor Homothorax in Drosophila
- (2011) Siew Woh Choo et al. PLoS One
- Genome-Wide Tissue-Specific Occupancy of the Hox Protein Ultrabithorax and Hox Cofactor Homothorax in Drosophila
- (2011) Matthew Slattery et al. PLoS One
- Evolution of a derived protein–protein interaction between HoxA11 and Foxo1a in mammals caused by changes in intramolecular regulation
- (2011) Kathryn J. Brayer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Variable motif utilization in homeotic selector (Hox)-cofactor complex formation controls specificity
- (2011) K. M. Lelli et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Interactions among Polycomb Domains Are Guided by Chromosome Architecture
- (2011) Bas Tolhuis et al. PLoS Genetics
- DNA Methylation Signatures Identify Biologically Distinct Subtypes in Acute Myeloid Leukemia
- (2010) Maria E. Figueroa et al. CANCER CELL
- GSK-3 Promotes Conditional Association of CREB and Its Coactivators with MEIS1 to Facilitate HOX-Mediated Transcription and Oncogenesis
- (2010) Zhong Wang et al. CANCER CELL
- Acute myeloid leukemia with mutated NPM1: diagnosis, prognosis and therapeutic perspectives
- (2010) Brunangelo Falini et al. CURRENT OPINION IN ONCOLOGY
- Connecting the transcription site to the nuclear pore: a multi-tether process that regulates gene expression
- (2010) G. Dieppois et al. JOURNAL OF CELL SCIENCE
- Hoxa9 Regulates Flt3 in Lymphohematopoietic Progenitors
- (2010) K. Gwin et al. JOURNAL OF IMMUNOLOGY
- Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
- (2010) Sven Heinz et al. MOLECULAR CELL
- New insights to the MLL recombinome of acute leukemias
- (2009) C Meyer et al. LEUKEMIA
- Altered nucleophosmin transport in acute myeloid leukaemia with mutated NPM1: molecular basis and clinical implications
- (2009) B Falini et al. LEUKEMIA
- The SWI/SNF complex and cancer
- (2009) D Reisman et al. ONCOGENE
- HOXA9 is required for survival in human MLL-rearranged acute leukemias
- (2008) J. Faber et al. BLOOD
- Modulation of murine embryonic stem cell-derived CD41+c-kit+ hematopoietic progenitors by ectopic expression of Cdx genes
- (2008) S. L. McKinney-Freeman et al. BLOOD
- Variation in Homeodomain DNA Binding Revealed by High-Resolution Analysis of Sequence Preferences
- (2008) Michael F. Berger et al. CELL
- Analysis of Homeodomain Specificities Allows the Family-wide Prediction of Preferred Recognition Sites
- (2008) Marcus B. Noyes et al. CELL
- Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation
- (2008) M. E. Dinger et al. GENOME RESEARCH
- Nucleophosmin Interacts with HEXIM1 and Regulates RNA Polymerase II Transcription
- (2008) Meera Gurumurthy et al. JOURNAL OF MOLECULAR BIOLOGY
- HOX expression patterns identify a common signature for favorable AML
- (2008) M Andreeff et al. LEUKEMIA
- HoxA9 induces insulin-like growth factor-1 receptor expression in B-lineage acute lymphoblastic leukemia
- (2008) J T Whelan et al. LEUKEMIA
- Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy
- (2008) Zhong Wang et al. NATURE
- Cdx gene deficiency compromises embryonic hematopoiesis in the mouse
- (2008) Y. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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