Th17 cytokines differentiate obesity from obesity-associated type 2 diabetes and promote TNFα production

T-Cell Profile in Adipose Tissue Is Associated With Insulin Resistance and Systemic Inflammation in Humans

(2014) Tracey McLaughlin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

T Cell–Derived IL-22 Amplifies IL-1β–Driven Inflammation in Human Adipose Tissue: Relevance to Obesity and Type 2 Diabetes

(2014) Elise Dalmas et al.   DIABETES

IL-21 Is a Major Negative Regulator of IRF4-Dependent Lipolysis Affecting Tregs in Adipose Tissue and Systemic Insulin Sensitivity

(2014) Marta Fabrizi et al.   DIABETES

Anti-inflammatory agents to treat or prevent type 2 diabetes, metabolic syndrome and cardiovascular disease

(2014) Nathalie Esser et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

HIV-1 infection induces strong production of IP-10 through TLR7/9-dependent pathways

(2013) Rachel P. Simmons et al.   AIDS

Class II Major Histocompatibility Complex Plays an Essential Role in Obesity-Induced Adipose Inflammation

(2013) Tuo Deng et al.   Cell Metabolism

Anti-CD3 clinical trials in type 1 diabetes mellitus

(2013) Anastasia G. Daifotis et al.   CLINICAL IMMUNOLOGY

Association Between Specific Adipose Tissue CD4+ T-Cell Populations and Insulin Resistance in Obese Individuals

(2013) Elisa Fabbrini et al.   GASTROENTEROLOGY

B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile

(2013) J. DeFuria et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD19+CD24hiCD38hi B Cells Maintain Regulatory T Cells While Limiting TH1 and TH17 Differentiation

(2013) F. Flores-Borja et al.   Science Translational Medicine

Induction and molecular signature of pathogenic TH17 cells

(2012) Youjin Lee et al.   NATURE IMMUNOLOGY

The imbalance of Th17/Th1/Tregs in patients with type 2 diabetes: relationship with metabolic factors and complications

(2011) Chun Zeng et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies

(2011) Daniel A Winer et al.   NATURE MEDICINE

In Vivo Systems Analysis Identifies Spatial and Temporal Aspects of the Modulation of TNF- -Induced Apoptosis and Proliferation by MAPKs

(2011) K. S. Lau et al.   Science Signaling

T cells in multiple sclerosis and experimental autoimmune encephalomyelitis

(2010) J. M. Fletcher et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Toll-like receptors regulate B cell cytokine production in patients with diabetes

(2010) M. Jagannathan et al.   DIABETOLOGIA

The Effects of Weight Loss and Gastric Banding on the Innate and Adaptive Immune System in Type 2 Diabetes and Prediabetes

(2010) A. Viardot et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Obesity Increases the Production of Proinflammatory Mediators from Adipose Tissue T Cells and Compromises TCR Repertoire Diversity: Implications for Systemic Inflammation and Insulin Resistance

(2010) H. Yang et al.   JOURNAL OF IMMUNOLOGY

Elevated Proinflammatory Cytokine Production by a Skewed T Cell Compartment Requires Monocytes and Promotes Inflammation in Type 2 Diabetes

(2010) M. Jagannathan-Bogdan et al.   JOURNAL OF IMMUNOLOGY

IL-17 Regulates Adipogenesis, Glucose Homeostasis, and Obesity

(2010) L. A. Zuniga et al.   JOURNAL OF IMMUNOLOGY

Induction treatment with monoclonal antibodies for heart transplantation

(2010) Juan F. Delgado et al.   Transplantation Reviews

Interleukin 17 Promotes Angiotensin II–Induced Hypertension and Vascular Dysfunction

(2009) Meena S. Madhur et al.   HYPERTENSION

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

(2009) Markus Feuerer et al.   NATURE MEDICINE

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

(2009) Satoshi Nishimura et al.   NATURE MEDICINE

Normalization of obesity-associated insulin resistance through immunotherapy

(2009) Shawn Winer et al.   NATURE MEDICINE

Interferon-γ, a Th1 Cytokine, Regulates Fat Inflammation

(2008) Viviane Zorzanelli Rocha et al.   CIRCULATION RESEARCH

Assessment of PLSDA cross validation

(2008) Johan A. Westerhuis et al.   Metabolomics