Multiple facets of histone variant H2AX: a DNA double-strand-break marker with several biological functions

Persistent DNA damage-induced premature senescence alters the functional features of human bone marrow mesenchymal stem cells

(2015) Valentina Minieri et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Histone Variant H2A.X Deposition Pattern Serves as a Functional Epigenetic Mark for Distinguishing the Developmental Potentials of iPSCs

(2014) Tao Wu et al.   Cell Stem Cell

Phosphorylation of Histone H2AX in the Mouse Brain from Development to Senescence

(2014) Serena Barral et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Interplay between the DNA Damage Proteins MDC1 and ATM in the Regulation of the Spindle Assembly Checkpoint

(2014) Yifat Eliezer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Organizing the genome with H2A histone variants

(2013) Catherine B. Millar   BIOCHEMICAL JOURNAL

γH2AX foci formation in the absence of DNA damage: Mitotic H2AX phosphorylation is mediated by the DNA-PKcs/CHK2 pathway

(2013) Wen-Zhi Tu et al.   FEBS LETTERS

Phosphorylated histone H2A.x in porcine embryos produced by IVF and somatic cell nuclear transfer

(2013) Rodrigo C Bohrer et al.   REPRODUCTION

The mortal strand hypothesis: Non-random chromosome inheritance and the biased segregation of damaged DNA

(2013) Gregory W. Charville et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Chromatin Remodeling Underlies the Senescence-Associated Secretory Phenotype of Tumor Stromal Fibroblasts That Supports Cancer Progression

(2012) E. Pazolli et al.   CANCER RESEARCH

The WSTF-ISWI Chromatin Remodeling Complex Transiently Associates with the Human Inactive X Chromosome during Late S-Phase Prior to BRCA1 and γ-H2AX

(2012) Ashley E. Culver-Cochran et al.   PLoS One

High Basal γH2AX Levels Sustain Self-Renewal of Mouse Embryonic and Induced Pluripotent Stem Cells

(2012) Valentina Turinetto et al.   STEM CELLS

Histone modifications and mitosis: countermarks, landmarks, and bookmarks

(2012) Fangwei Wang et al.   TRENDS IN CELL BIOLOGY

Nucleosome Structure(s) and Stability: Variations on a Theme

(2011) Andrew J. Andrews et al.   Annual Review of Biophysics

Wdr5 Mediates Self-Renewal and Reprogramming via the Embryonic Stem Cell Core Transcriptional Network

(2011) Yen-Sin Ang et al.   CELL

Chromatin Connections to Pluripotency and Cellular Reprogramming

(2011) Stuart H. Orkin et al.   CELL

Activation of DNA damage response signaling in mouse embryonic stem cells

(2011) Ilya A. Chuykin et al.   CELL CYCLE

DNA damage responses by human ELG1 in S phase are important to maintain genomic integrity

(2011) Nilabja Sikdar et al.   CELL CYCLE

MDC1 directs chromosome-wide silencing of the sex chromosomes in male germ cells

(2011) Y. Ichijima et al.   GENES & DEVELOPMENT

BRCA1 tumour suppression occurs via heterochromatin-mediated silencing

(2011) Quan Zhu et al.   NATURE

Cell cycle restriction by histone H2AX limits proliferation of adult neural stem cells

(2011) R. N. Fernando et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA-PKcs plays a dominant role in the regulation of H2AX phosphorylation in response to DNA damage and cell cycle progression

(2010) Jing An et al.   BMC MOLECULAR BIOLOGY

Mad2 Prolongs DNA Damage Checkpoint Arrest Caused by a Double-Strand Break via a Centromere-Dependent Mechanism

(2010) Farokh Dotiwala et al.   CURRENT BIOLOGY

Chromatin plasticity and genome organization in pluripotent embryonic stem cells

(2010) Anna Mattout et al.   CURRENT OPINION IN CELL BIOLOGY

Changes in the nuclear deposition of histone H2A variants during pre-implantation development in mice

(2010) B. Nashun et al.   DEVELOPMENT

Expression of genes coding for histone variants and histone-associated proteins in pluripotent stem cells and mouse preimplantation embryos

(2010) Georgia R. Kafer et al.   GENE EXPRESSION PATTERNS

Phosphorylation of Histone H2A.X by DNA-dependent Protein Kinase Is Not Affected by Core Histone Acetylation, but It Alters Nucleosome Stability and Histone H1 Binding

(2010) Andra Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion

(2010) F. Rodier et al.   JOURNAL OF CELL SCIENCE

Histone variants — ancient wrap artists of the epigenome

(2010) Paul B. Talbert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The BRG1 ATPase of chromatin remodeling complexes is involved in modulation of mesenchymal stem cell senescence through RB–P53 pathways

(2010) N Alessio et al.   ONCOGENE

Nuclear Organization and Dosage Compensation

(2010) J. C. Chow et al.   Cold Spring Harbor Perspectives in Biology

The X as Model for RNA's Niche in Epigenomic Regulation

(2010) J. T. Lee   Cold Spring Harbor Perspectives in Biology

Distribution of p53 binding protein 1 (53BP1) and phosphorylated H2A.X during mouse preimplantation development in the absence of DNA damage

(2009) Celine Ziegler-Birling et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Characterisation of histone variant distribution in human embryonic stem cells by transfection of in vitro transcribed mRNA

(2009) Margaret L. Shaw et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Asymmetric centrosome inheritance maintains neural progenitors in the neocortex

(2009) Xiaoqun Wang et al.   NATURE

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY

Epigenetic inheritance during the cell cycle

(2009) Aline V. Probst et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Biased segregation of DNA and centrosomes — moving together or drifting apart?

(2009) Shahragim Tajbakhsh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A distinct H2A.X isoform is enriched in Xenopus laevis eggs and early embryos and is phosphorylated in the absence of a checkpoint

(2009) David Shechter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Nucleosome Family: Dynamic and Growing

(2009) Jordanka Zlatanova et al.   STRUCTURE

Explanation for excessive DNA single-strand breaks and endogenous repair foci in pluripotent mouse embryonic stem cells

(2008) J.P. Banáth et al.   EXPERIMENTAL CELL RESEARCH

FACT-Mediated Exchange of Histone Variant H2AX Regulated by Phosphorylation of H2AX and ADP-Ribosylation of Spt16

(2008) Kyu Heo et al.   MOLECULAR CELL

Histone H2AX-dependent GABAA receptor regulation of stem cell proliferation

(2008) Michael Andäng et al.   NATURE