Importin-β facilitates nuclear import of human GW proteins and balances cytoplasmic gene silencing protein levels

Assembly and function of small RNA – Argonaute protein complexes

(2014) Anne Dueck et al.   BIOLOGICAL CHEMISTRY

Importin 8 Regulates the Transport of Mature MicroRNAs into the Cell Nucleus

(2014) Yao Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A DDX6-CNOT1 Complex and W-Binding Pockets in CNOT9 Reveal Direct Links between miRNA Target Recognition and Silencing

(2014) Ying Chen et al.   MOLECULAR CELL

Structural and Biochemical Insights to the Role of the CCR4-NOT Complex and DDX6 ATPase in MicroRNA Repression

(2014) Hansruedi Mathys et al.   MOLECULAR CELL

siPools: highly complex but accurately defined siRNA pools eliminate off-target effects

(2014) Michael Hannus et al.   NUCLEIC ACIDS RESEARCH

Structural basis for microRNA targeting

(2014) N. T. Schirle et al.   SCIENCE

Import routes and nuclear functions of Argonaute and other small RNA-silencing proteins

(2014) Daniel Schraivogel et al.   TRENDS IN BIOCHEMICAL SCIENCES

RNAi Factors Are Present and Active in Human Cell Nuclei

(2014) Keith T. Gagnon et al.   Cell Reports

hCAF1/CNOT7 regulates interferon signalling by targeting STAT1

(2013) Clément Chapat et al.   EMBO JOURNAL

RNA interference in the nucleus: roles for small RNAs in transcription, epigenetics and beyond

(2013) Stephane E. Castel et al.   NATURE REVIEWS GENETICS

Argonaute proteins: functional insights and emerging roles

(2013) Gunter Meister   NATURE REVIEWS GENETICS

Turning catalytically inactive human Argonaute proteins into active slicer enzymes

(2013) Judith Hauptmann et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular dissection of human Argonaute proteins by DNA shuffling

(2013) Nina Schürmann et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural features of Argonaute-GW182 protein interactions

(2013) J. Pfaff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The double-stranded RNA binding domain of human Dicer functions as a nuclear localization signal

(2013) M. Doyle et al.   RNA

Eukaryotic Argonautes come into focus

(2013) Claus-D. Kuhn et al.   TRENDS IN BIOCHEMICAL SCIENCES

Eukaryote-Specific Insertion Elements Control Human ARGONAUTE Slicer Activity

(2013) Kotaro Nakanishi et al.   Cell Reports

The Making of a Slicer: Activation of Human Argonaute-1

(2013) Christopher R. Faehnle et al.   Cell Reports

Systematic analysis of barrier-forming FG hydrogels from Xenopus nuclear pore complexes

(2012) Aksana A Labokha et al.   EMBO JOURNAL

Kinetic analysis reveals successive steps leading to miRNA-mediated silencing in mammalian cells

(2012) Julien Béthune et al.   EMBO REPORTS

Quantitative functions of Argonaute proteins in mammalian development

(2012) D. Wang et al.   GENES & DEVELOPMENT

mRNA Decapping Factors and the Exonuclease Xrn2 Function in Widespread Premature Termination of RNA Polymerase II Transcription

(2012) Kris Brannan et al.   MOLECULAR CELL

Structure of yeast Argonaute with guide RNA

(2012) Kotaro Nakanishi et al.   NATURE

Control of somatic tissue differentiation by the long non-coding RNA TINCR

(2012) Markus Kretz et al.   NATURE

Senescence is an endogenous trigger for microRNA-directed transcriptional gene silencing in human cells

(2012) Moussa Benhamed et al.   NATURE CELL BIOLOGY

Human TNRC6A is an Argonaute-navigator protein for microRNA-mediated gene silencing in the nucleus

(2012) K. Nishi et al.   RNA

miRNA-Mediated Gene Silencing by Translational Repression Followed by mRNA Deadenylation and Decay

(2012) S. Djuranovic et al.   SCIENCE

Ribosome Profiling Shows That miR-430 Reduces Translation Before Causing mRNA Decay in Zebrafish

(2012) A. A. Bazzini et al.   SCIENCE

Ran-dependent nuclear export mediators: a structural perspective

(2011) Thomas Güttler et al.   EMBO JOURNAL

Gene silencing by microRNAs: contributions of translational repression and mRNA decay

(2011) Eric Huntzinger et al.   NATURE REVIEWS GENETICS

PIWI-interacting small RNAs: the vanguard of genome defence

(2011) Mikiko C. Siomi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Increased siRNA duplex stability correlates with reduced off-target and elevated on-target effects

(2011) S. Petri et al.   RNA

7SK snRNA: a noncoding RNA that plays a major role in regulating eukaryotic transcription

(2011) B. Matija Peterlin et al.   Wiley Interdisciplinary Reviews-RNA

The widespread regulation of microRNA biogenesis, function and decay

(2010) Jacek Krol et al.   NATURE REVIEWS GENETICS

Phosphorylation of human Argonaute proteins affects small RNA binding

(2010) Sabine Rüdel et al.   NUCLEIC ACIDS RESEARCH

Involvement of argonaute proteins in gene silencing and activation by RNAs complementary to a non-coding transcript at the progesterone receptor promoter

(2010) Yongjun Chu et al.   NUCLEIC ACIDS RESEARCH

The GW/WG repeats of Drosophila GW182 function as effector motifs for miRNA-mediated repression

(2010) Marina Chekulaeva et al.   NUCLEIC ACIDS RESEARCH

Cellular oxygen sensing: Importins and exportins are mediators of intracellular localisation of prolyl-4-hydroxylases PHD1 and PHD2

(2009) Amrei Steinhoff et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Importin 8 Is a Gene Silencing Factor that Targets Argonaute Proteins to Distinct mRNAs

(2009) Lasse Weinmann et al.   CELL

Functional Dissection of the Human TNRC6 (GW182-Related) Family of Proteins

(2009) D. Baillat et al.   MOLECULAR AND CELLULAR BIOLOGY

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mammalian GW182 contains multiple Argonaute-binding sites and functions in microRNA-mediated translational repression

(2009) K. Takimoto et al.   RNA

The C-terminal half of human Ago2 binds to multiple GW-rich regions of GW182 and requires GW182 to mediate silencing

(2009) S. L. Lian et al.   RNA

GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay

(2008) Ana Eulalio et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A multifunctional human Argonaute2-specific monoclonal antibody

(2008) S. Rudel et al.   RNA

An Argonaute Transports siRNAs from the Cytoplasm to the Nucleus

(2008) S. Guang et al.   SCIENCE

Argonaute proteins: key players in RNA silencing

(2007) Gyorgy Hutvagner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY