Expression of T-cell KV1.3 potassium channel correlates with pro-inflammatory cytokines and disease activity in ulcerative colitis

Reduction of CD68+ Macrophages and Decreased IL-17 Expression in Intestinal Mucosa of Patients with Inflammatory Bowel Disease Strongly Correlate With Endoscopic Response and Mucosal Healing following Infliximab Therapy

(2013) Flavio Caprioli et al.   INFLAMMATORY BOWEL DISEASES

Effect of IL-17A blockade with secukinumab in autoimmune diseases

(2012) Dhavalkumar D Patel et al.   ANNALS OF THE RHEUMATIC DISEASES

NS6180, a new KCa3.1 channel inhibitor prevents T-cell activation and inflammation in a rat model of inflammatory bowel disease

(2012) D Strøbaek et al.   BRITISH JOURNAL OF PHARMACOLOGY

Molecular regulation of CRAC channels and their role in lymphocyte function

(2012) Patrick J. Shaw et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Kv1.3 Deletion Biases T Cells toward an Immunoregulatory Phenotype and Renders Mice Resistant to Autoimmune Encephalomyelitis

(2012) A. R. Gocke et al.   JOURNAL OF IMMUNOLOGY

Ulcerative colitis

(2012) Ingrid Ordás et al.   LANCET

KCa3.1 and TRPM7 Channels at the Uropod Regulate Migration of Activated Human T Cells

(2012) Zerrin Kuras et al.   PLoS One

TH1 and TH17 interactions in untreated inflamed mucosa of inflammatory bowel disease, and their potential to mediate the inflammation

(2011) Trine Olsen et al.   CYTOKINE

The lymphocyte potassium channels Kv1.3 and KCa3.1 as targets for immunosuppression

(2011) Jenny Lam et al.   DRUG DEVELOPMENT RESEARCH

Ulcerative Colitis

(2011) Silvio Danese et al.   NEW ENGLAND JOURNAL OF MEDICINE

Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases

(2011) Victor Chi et al.   TOXICON

Inflammatory bowel disease: role of diet, microbiota, life style

(2011) Manuela G. Neuman et al.   Translational Research

Lymphocyte activation in type 1 diabetes mellitus: The increased significance of Kv1.3 potassium channels

(2010) Gergely Toldi et al.   IMMUNOLOGY LETTERS

Pivotal Advance: Nonfunctional lung effectors exhibit decreased calcium mobilization associated with reduced expression of ORAI1

(2010) Subhashini Arimilli et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Inhibition of the K+ channel KCa3.1 ameliorates T cell-mediated colitis

(2010) L. Di et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Environmental risk factors in inflammatory bowel diseases. Investigating the hygiene hypothesis: A Spanish case–control study

(2010) Pilar López-Serrano et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

(2009) S. A. Bustin et al.   CLINICAL CHEMISTRY

Senicapoc (ICA-17043): a potential therapy for the prevention and treatment of hemolysis-associated complications in sickle cell anemia

(2009) Kenneth I Ataga et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

The functional network of ion channels in T lymphocytes

(2009) Michael D. Cahalan et al.   IMMUNOLOGICAL REVIEWS

A protective function for interleukin 17A in T cell–mediated intestinal inflammation

(2009) William O'Connor Jr et al.   NATURE IMMUNOLOGY

Calcium signaling in lymphocytes

(2008) Masatsugu Oh-hora et al.   CURRENT OPINION IN IMMUNOLOGY

Infectious Gastroenteritis and Risk of Developing Inflammatory Bowel Disease

(2008) Chad K. Porter et al.   GASTROENTEROLOGY

The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation

(2008) Wenjun Ouyang et al.   IMMUNITY

Molecular Clustering of STIM1 with Orai1/CRACM1 at the Plasma Membrane Depends Dynamically on Depletion of Ca2+ Stores and on Electrostatic Interactions

(2008) Nathaniel Calloway et al.   MOLECULAR BIOLOGY OF THE CELL