Results of the 2nd Scientific Workshop of the ECCO (III): Basic mechanisms of intestinal healing

Enterocyte-Derived TAK1 Signaling Prevents Epithelium Apoptosis and the Development of Ileitis and Colitis

(2014) R. Kajino-Sakamoto et al.   JOURNAL OF IMMUNOLOGY

Inflammation-Induced Endothelial-to-Mesenchymal Transition

(2011) Florian Rieder et al.   AMERICAN JOURNAL OF PATHOLOGY

Reduction of disulphide bonds unmasks potent antimicrobial activity of human β-defensin 1

(2011) Bjoern O. Schroeder et al.   NATURE

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

(2011) Carl A Anderson et al.   NATURE GENETICS

PI3K-Dependent GSK3ß(Ser9)-Phosphorylation Is Implicated in the Intestinal Epithelial Cell Wound-Healing Response

(2011) Thomas Karrasch et al.   PLoS One

Phosphatidylcholine as a constituent in the colonic mucosal barrier—Physiological and clinical relevance

(2010) Robert Ehehalt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Delayed release phosphatidylcholine as new therapeutic drug for ulcerative colitis – a review of three clinical trials

(2010) Wolfgang Stremmel et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Sphingomyelin induces cathepsin D-mediated apoptosis in intestinal epithelial cells and increases inflammation in DSS colitis

(2010) A. Fischbeck et al.   GUT

Interferon-γ Regulates Intestinal Epithelial Homeostasis through Converging β-Catenin Signaling Pathways

(2010) Porfirio Nava et al.   IMMUNITY

Reciprocal changes of Foxp3 expression in blood and intestinal mucosa in IBD patients responding to infliximab†

(2010) Zhe Li et al.   INFLAMMATORY BOWEL DISEASES

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon

(2010) L. Peyrin-Biroulet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of  -Catenin in Dendritic Cells Regulates Immunity Versus Tolerance in the Intestine

(2010) S. Manicassamy et al.   SCIENCE

From mechanotransduction to extracellular matrix gene expression in fibroblasts

(2009) Matthias Chiquet et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Targeting Matrix Metalloproteinases in Inflammatory Conditions

(2009) A. Clutterbuck et al.   CURRENT DRUG TARGETS

Nuclear factor-kappa B in intestinal protection and destruction

(2009) Martina E Spehlmann et al.   CURRENT OPINION IN GASTROENTEROLOGY

Stromelysin-1 and macrophage metalloelastase expression in the intestinal mucosa of Crohnʼs disease patients treated with infliximab

(2009) Antonio Di Sabatino et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

A complex, but uniform O-glycosylation of the human MUC2 mucin from colonic biopsies analyzed by nanoLC/MSn

(2009) Jessica M Holmén Larsson et al.   GLYCOBIOLOGY

Mucosal gene signatures to predict response to infliximab in patients with ulcerative colitis

(2009) I. Arijs et al.   GUT

Alterations of phospholipid concentration and species composition of the intestinal mucus barrier in ulcerative colitis: A clue to pathogenesis

(2009) Annika Braun et al.   INFLAMMATORY BOWEL DISEASES

Enhanced translocation of bacteria across metabolically stressed epithelia is reduced by butyrate†

(2009) Kimberley Lewis et al.   INFLAMMATORY BOWEL DISEASES

Intestinal barrier function: Molecular regulation and disease pathogenesis

(2009) Katherine R. Groschwitz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

CCR6 Regulation of the Actin Cytoskeleton Orchestrates Human Beta Defensin-2- and CCL20-mediated Restitution of Colonic Epithelial Cells

(2009) Rebecca A. Vongsa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Butyrate Enhances the Intestinal Barrier by Facilitating Tight Junction Assembly via Activation of AMP-Activated Protein Kinase in Caco-2 Cell Monolayers

(2009) Luying Peng et al.   JOURNAL OF NUTRITION

High Levels of Proinflammatory Cytokines, but Not Markers of Tissue Injury, in Unaffected Intestinal Areas from Patients with IBD

(2009) Alberto J. León et al.   MEDIATORS OF INFLAMMATION

Intestinal fibrosis in IBD—a dynamic, multifactorial process

(2009) Florian Rieder et al.   Nature Reviews Gastroenterology & Hepatology

Mucosal Gene Expression of Antimicrobial Peptides in Inflammatory Bowel Disease Before and After First Infliximab Treatment

(2009) Ingrid Arijs et al.   PLoS One

Probiotics promote gut health through stimulation of epithelial innate immunity

(2009) C. Pagnini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Wound Healing Responses at the Gastrointestinal Epithelium: a Close Look at Novel Regulatory Factors and Investigative Approaches

(2009) T. Karrasch et al.   ZEITSCHRIFT FUR GASTROENTEROLOGIE

Diagnosis and management of fistulizing Crohn's disease

(2009) Ole Haagen Nielsen et al.   Nature clinical practice. Gastroenterology & hepatology

XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease

(2008) Arthur Kaser et al.   CELL

Inhibitory Effects of Short-Chain Fatty Acids on Matrix Metalloproteinase Secretion from Human Colonic Subepithelial Myofibroblasts

(2008) Takato Kawamura et al.   DIGESTIVE DISEASES AND SCIENCES

Luminal Antioxidants Enhance the Effects of Mesalamine in the Treatment of Chemically Induced Colitis in Rats

(2008) Hanumantha R. Ancha et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Hypoxia-Inducible Factor Augments Experimental Colitis Through an MIF–Dependent Inflammatory Signaling Cascade

(2008) Yatrik M. Shah et al.   GASTROENTEROLOGY

The ErbB4 Growth Factor Receptor Is Required for Colon Epithelial Cell Survival in the Presence of TNF

(2008) Mark R. Frey et al.   GASTROENTEROLOGY

Mechanisms of action of probiotics: Recent advances

(2008) S. C. Ng et al.   INFLAMMATORY BOWEL DISEASES

Human beta defensin 2 promotes intestinal wound healing in vitro

(2008) Jan-Michel Otte et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Smad3 knockout mice exhibit impaired intestinal mucosal healing

(2008) Cheri R Owen et al.   LABORATORY INVESTIGATION

Combined defects in epithelial and immunoregulatory factors exacerbate the pathogenesis of inflammation: mucin 2-interleukin 10-deficient mice

(2008) Maria van der Sluis et al.   LABORATORY INVESTIGATION

Barrier dysfunction due to distinct defensin deficiencies in small intestinal and colonic Crohn's disease

(2008) J Wehkamp et al.   Mucosal Immunology

Transactivation of EGF receptor and ErbB2 protects intestinal epithelial cells from TNF-induced apoptosis

(2008) T. Yamaoka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient colonic mucosal wound repair requires Trem2 signaling

(2008) H. Seno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

(2008) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protective effect of ilomastat on trinitrobenzenesulfonic acid-induced ulcerative colitis in rats

(2008) Ying-De Wang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Epithelial restitution and wound healing in inflammatory bowel disease

(2008) Andreas Sturm et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Mucosal Protection by Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition

(2007) Andreas Robinson et al.   GASTROENTEROLOGY

NF-κB and the intestine: Friend or foe?

(2007) Thomas Karrasch et al.   INFLAMMATORY BOWEL DISEASES

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY