Article
Psychiatry
Annika Tiger, Anna Ohlis, Johan Bjureberg, Sebastian Lundstrom, Paul Lichtenstein, Henrik Larsson, Clara Hellner, Ralf Kuja-Halkola, Nitya Jayaram-Lindstrom
Summary: This study investigated the association between childhood ADHD symptoms and subsequent development of BPD. The findings suggest that impulsivity is the most prominent subdimension of childhood ADHD in relation to BPD.
ACTA PSYCHIATRICA SCANDINAVICA
(2022)
Article
Clinical Neurology
Min Eun Jeon, Marielle M. Gomez, Rochelle A. Stewart, Thomas E. Joiner
Summary: This study aims to examine the symptom structure of Acute Suicidal Affective Disturbance (ASAD) and compare it with Borderline Personality Disorder (BPD). The results suggest that while there are some symptom correlations between ASAD and BPD, most symptoms are distinct.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Clinical Neurology
J. Lumikukka Socada, John J. Soderholm, Tom Rosenstrom, Jesper Ekelund, Erkki Isometsa
Summary: This study investigated the prevalence, severity, co-occurrence, and overlap of manic symptoms and borderline personality features in unipolar and bipolar major depressive episodes. The results showed that the presence of mixed and borderline features in MDEs is common, with differences in diagnosis-specific features among different subcohorts. The study highlighted the impact of hypomania on perceived BPD features and the correlation between manic symptoms and borderline features.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Karen Kelley, Maggie Walgren, Hilary L. DeShong
Summary: This study found that anger rumination is the strongest predictor of both antisocial and borderline symptoms, while worry negatively predicts antisocial symptoms. Rumination and worry explain far more variance in borderline symptoms compared to antisocial symptoms.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Review
Clinical Neurology
Chiara Penengo, Chiara Colli, Carolina Bonivento, Andrea Boscutti, Matteo Balestrieri, Giuseppe Delvecchio, Paolo Brambilla
Summary: This review summarizes ERP studies on BPD, finding altered positive ERP amplitudes, latencies, and loudness dependence in BPD patients, possibly reflecting deficits in attention and executive functions.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Psychiatry
Emily R. Edwards, Nina L. J. Rose, Molly Gromatsky, Abigail Feinberg, David Kimhy, John T. Doucette, Marianne Goodman, Margaret M. McClure, M. Mercedes Perez-Rodriguez, Antonia S. New, Erin A. Hazlett
Summary: The study found that affective lability and alexithymia are key factors in understanding the relationship between childhood adversity and BPD, which is crucial for interventions targeting this population.
JOURNAL OF PERSONALITY DISORDERS
(2021)
Article
Psychiatry
Sylvia Martin, Jonathan Del -Monte
Summary: This study investigated the relationship between Metacognition, Insight, Impulsivity, and Borderline Personality Disorder (BPD) in 190 BPD patients. The results showed significant associations between BPD and both Insight and Metacognition. Metacognition was found to be significantly correlated with certain dimensions of Impulsivity, while Insight was correlated with most of them. Regression analysis revealed a significant relationship between Insight, Metacognition, Impulsivity, and Borderline traits. Mediation analysis proved the indirect effect of Metacognition/Insight on Borderline traits through Impulsivity. This study highlights the importance of Metacognition and Insight in understanding and treating BPD, despite limitations in gender representation and possible comorbidity issues.
JOURNAL OF PSYCHIATRIC RESEARCH
(2023)
Article
Chemistry, Analytical
Alessandro Grecucci, Harold Dadomo, Gerardo Salvato, Gaia Lapomarda, Sara Sorella, Irene Messina
Summary: This study applied a combination of unsupervised and supervised machine learning approaches to identify gray-white matter circuits associated with borderline personality disorder (BPD), which can accurately distinguish BPD patients from healthy controls and are related to early traumatic experiences and specific symptoms.
Article
Psychiatry
Nicole D. Cardona, Christina M. Temes, Laura R. Magni, Katherine E. Hein, Blaise A. Aguirre, Marianne Goodman, Mary C. Zanarini
Summary: Adolescents with BPD report more severe symptoms of affective lability, impulsivity, and aggression compared to their peers, and similar symptom severity to adults with BPD but with less severe verbal aggression and anger. They are distinguishable from typically developing adolescents based on self-reported affective and behavioral symptoms, and may experience these symptoms at a severity comparable to adult counterparts.
JOURNAL OF PERSONALITY DISORDERS
(2021)
Article
Clinical Neurology
Benedetta Vai, Silvia Cazzetta, Rosalia Scalisi, Alessia Donati, Margherita Bechi, Sara Poletti, Laura Sforzini, Raffaele Visintini, Cesare Maffei, Francesco Benedetti
Summary: The study revealed deficits in verbal memory, working memory, attention, information processing speed, and psychomotor speed and coordination in BPD patients, with the impairment in psychomotor abilities remaining significant after controlling for medication load. A multiple regression analysis confirmed the impact of psychomotor abilities on the severity of BPD symptoms. The study suggests a potential clinical benefit of cognitive remediation programs in BPD.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Review
Psychiatry
Alessandra D'Agostino, Raffaele Pepi, Vladan Starcevic
Summary: This review examines the current state of knowledge about borderline personality disorder (BPD) in older adults and the elderly. Studies have found a decrease in the prevalence of BPD among ageing individuals, potentially due to the ageing process and changes in clinical features. Older individuals with BPD may present with attenuated and less overt manifestations of impulsivity, but still exhibit overall symptom instability.
CURRENT OPINION IN PSYCHIATRY
(2022)
Article
Psychiatry
Mohamed Nasreldin Sadek, Esraa Shehata Ismail, Ayman Isamil Kamel, Alia Adel Saleh, Ayda Aly Youssef, Nagwan Mohamed Madbouly
Summary: The study revealed significant structural alterations in the corpus callosum of adolescent females with Borderline Personality Disorder, which are associated with symptoms of emotional dysregulation and impulsivity.
JOURNAL OF PSYCHIATRIC RESEARCH
(2021)
Review
Medicine, General & Internal
Tina Wu, Jennifer Hu, Dimitry Davydow, Heather Huang, Margaret Spottswood, Hsiang Huang
Summary: Borderline personality disorder is a common mental health diagnosis observed in the primary care population and is associated with various challenges in diagnosis and treatment. This article aims to describe the impact of BPD in primary care, review current knowledge, and provide evidence-based treatment approaches for these patients.
FRONTIERS IN MEDICINE
(2022)
Article
Neurosciences
Ashley C. Parr, Olivia G. Calancie, Brian C. Coe, Sarosh Khalid-Khan, Douglas P. Munoz
Summary: The study found that patients with borderline personality disorder exhibited fewer reinforcement learning biases, increased variability in reaction times, and more anticipatory decisions in mixed-strategy decision-making. Patients with high impulsivity had higher reward rates and stronger outcome modulation, while those with high emotional dysregulation showed increased reward rates and choice pattern entropy.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Psychology, Clinical
J. S. Wrege, D. Carcone, A. C. H. Lee, C. Cane, U. E. Lang, S. Borgwardt, M. Walter, A. C. Ruocco
Summary: Patients with BPD show disruptions in frontoparietal regions related to a combination of response inhibition and attentional saliency or saliency processing alone. However, there are no specific neural activation differences related to response inhibition when attentional saliency is controlled. This suggests a neural dysfunction in BPD specifically underlying attention to salient or infrequent stimuli, supported by a negative correlation with self-rated impulsiveness.
PSYCHOLOGICAL MEDICINE
(2022)
Article
Health Care Sciences & Services
Chamberlain Mbah, Jan De Neve, Olivier Thas
STATISTICAL METHODS IN MEDICAL RESEARCH
(2019)
Article
Mathematical & Computational Biology
Jan De Neve, Olivier Thas, Thomas A. Gerds
STATISTICS IN MEDICINE
(2019)
Article
Environmental Sciences
Long Ho, Olivier Thas, Wout Van Echelpoel, Peter Goethals
Article
Veterinary Sciences
I. Thas, R. A. Wagner, O. Thas
JOURNAL OF SMALL ANIMAL PRACTICE
(2019)
Article
Psychiatry
Chris Baeken, Guo-Rong Wu, Kees van Heeringen
TRANSLATIONAL PSYCHIATRY
(2019)
Article
Biochemical Research Methods
Alemu Takele Assefa, Jo Vandesompele, Olivier Thas
Article
Biochemical Research Methods
Celine Everaert, Pieter-Jan Volders, Annelien Morlion, Olivier Thas, Pieter Mestdagh
BMC BIOINFORMATICS
(2020)
Article
Biotechnology & Applied Microbiology
Alemu Takele Assefa, Jo Vandesompele, Olivier Thas
Article
Multidisciplinary Sciences
Stijn Hawinkel, J. C. W. Rayner, Luc Bijnens, Olivier Thas
Article
Biochemical Research Methods
Charis Du Cheyne, Yao Chen, Jurgen De Craene, Olivier Thas, Ward De Spiegelaere
Summary: Accurate tools for measuring RNA integrity are crucial for reliable gene expression data. A triplex dPCR 3':5' assay has been developed as a rapid and simple alternative to RT-qPCR for assessing RNA integrity in equine samples. This assay not only provides a straightforward analysis of mRNA integrity, but also its quantity.
ANALYTICAL BIOCHEMISTRY
(2021)
Article
Statistics & Probability
J. C. W. Rayner, Paul Rippon, Thomas Suesse, Olivier Thas
Summary: This study focuses on the conditional mean and distribution assumptions in regression models, proposing a smooth goodness of fit test to examine the distribution assumption. By embedding the regression model in a smooth family of alternatives and constructing appropriate score tests, this method accurately accounts for nuisance parameter estimation. The approach is customizable, focused, and comprehensive, with wide applicability and the ability to detect important deviations from the hypothesized model.
AUSTRALIAN & NEW ZEALAND JOURNAL OF STATISTICS
(2022)
Article
Psychiatry
Eva De Jaegere, Pauline Stas, Kees van Heeringen, Eva Dumon, Renate van Landschoot, Gwendolyn Portzky
Summary: This study investigates the short-term and long-term effects of Future-Oriented Group Training (FOGT) on suicidal thoughts and related variables. The results show that compared to the control group, the intervention group significantly decreases worrying and increases future-oriented thinking at posttreatment and follow-up. Changes in suicidal ideation, depression, hopelessness, and future-oriented thinking remained significant at follow-up. This study provides promising empirical evidence for the use of FOGT for individuals with suicidal ideation.
SUICIDE AND LIFE-THREATENING BEHAVIOR
(2023)
Article
Psychiatry
Eva De Jaegere, Eva Dumon, Kees van Heeringen, Renate van Landschoot, Pauline Stas, Gwendolyn Portzky
Summary: This study investigated the effectiveness of MBCT adapted to individuals at risk for suicide, and found that MBCT-S may have the potential to reduce suicidal ideation and suicide-related factors compared to usual treatment.
ARCHIVES OF SUICIDE RESEARCH
(2023)
Article
Psychology, Clinical
Eva De Jaegere, Renate van Landschoot, Kees van Heeringen, Bregje A. J. van Spijker, Ad J. F. M. Kerkhof, Jan K. Mokkenstorm, Gwendolyn Portzky
BEHAVIOUR RESEARCH AND THERAPY
(2019)
Article
Biochemical Research Methods
Stijn Hawinkel, Federico Mattiello, Luc Bijnens, Olivier Thas
BRIEFINGS IN BIOINFORMATICS
(2019)