Article
Food Science & Technology
Hong-Wei Li, Yi-Zhou Xiang, Man Zhang, Yu-Hang Jiang, Yao Zhang, Ying-Yang Liu, Lian-Bing Lin, Qi-Lin Zhang
Summary: The study identified a novel bacteriocin XJS01 with potential activity against foodborne Staphylococcus aureus. XJS01 exhibited low minimum inhibitory concentration and good resistance to heat treatment, leading to significant inhibition of both planktonic cells and biofilm formation of S. aureus. The bacteriocin impaired membrane permeability, caused cytoplasmic content leakage, and induced cell deformation in S. aureus.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Yi Hong, Zhou Zhou, Lingzi Yu, Keyang Jiang, Jiamiao Xia, Yuling Mi, Caiqiao Zhang, Jian Li
Summary: The feeding of L. salivarius + L. agilis in hens can improve egg-laying rate, egg weight, and albumen's amino acid levels, as well as enhance intestinal microflora and metabolism profile.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Food Science & Technology
Yan-Mei Zhang, Yu-Hang Jiang, Hong-Wei Li, Xiu-Zhang Li, Qi-Lin Zhang
Summary: S. argenteus is a pathogen that can cause food poisoning, and its biofilms pose a potential risk to food safety. This study introduces a novel bacteriocin, LSB1, derived from Lactobacillus plantarum CGMCC 1.12934, which exhibits strong antibacterial and antibiofilm activity against S. argenteus. LSB1 shows excellent stability and a wide antimicrobial spectrum, making it a potential natural food preservative.
JOURNAL OF FOOD SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Wenqian Huang, Yirong Zhang, Zhi Li, Minjie Li, Fangfang Li, Monika Mortimer, Liang-Hong Guo
Summary: Medical applications of nanotechnology show promise, but the effects of nanodrugs on human microbiota have not been fully considered. This study found that medically relevant nanoparticles can affect the metabolism of beneficial bacteria and potentially alter the microbiota and immune signaling.
Article
Fisheries
Ratchanu Meidong, Miki Nakao, Kenji Sakai, Saowanit Tongpim
Summary: Probiotics, particularly the strain Lactobacillus paraplantarum L34b-2, showed significant benefits in promoting growth, enhancing innate immune responses, and improving disease resistance in Pangasius bocourti. This strain not only improved weight gain and growth rate in fish, but also increased important immune parameters and enhanced survival rates after infection with a virulent pathogen.
Article
Microbiology
M. E. Arnal, S. Denis, O. Uriot, C. Lambert, S. Holowacz, F. Paul, S. Kuylle, B. Pereira, M. Alric, S. Blanquet-Diot
Summary: The study used two in vitro models of the human gut, TIM-1 and ARCOL, to investigate the effects of three oral formulations of a Lactobacillus salivarius strain on viability and interactions with gut microbiota. The sustained-release tablet emerged as the most effective in preserving the strain's viability during gastrointestinal transit. However, the capsule and powder formulations showed lower survival rates, with no significant differences in their modulation of gut microbiota composition and activity.
BENEFICIAL MICROBES
(2021)
Article
Food Science & Technology
Bindiya Ellathuparambil Saidumohamed, Sarita Ganapathy Bhat
Summary: Probiotics, such as Bacillus safensis SDG14, are considered functional food due to their health benefits beyond traditional nutrition. These probiotics are non-pathogenic, spore forming, pH and bile salt resistant, and capable of producing bacteriocin, amino acids, and vitamins, making them suitable for food and feed applications.
FOOD RESEARCH INTERNATIONAL
(2021)
Article
Agriculture, Multidisciplinary
R. Yasmeen, A. S. Hashmi, M. Athar, M. Tayyab, A. A. Anjum
Summary: This study explored alternative media for the growth of Lactobacillus salivarius by supplementing milk products with industrial waste. It was found that the addition of Corn Steep Liquor (CSL), Yeast Sludge (YS), and glucose to Fermented Whey Powder (FWP) medium proved to be the most effective for the growth of L. salivarius.
JOURNAL OF ANIMAL AND PLANT SCIENCES-JAPS
(2022)
Article
Microbiology
Zhou Zhou, Lingzi Yu, Jiajia Cao, Jiaming Yu, Zhibo Lin, Yi Hong, Sibo Jiang, Cong Chen, Yuling Mi, Caiqiao Zhang, Jian Li
Summary: In this study, the researchers found that the supernatant of Lactobacillus salivarius can directly promote the activity of intestinal stem cells. Further investigation revealed that succinate, a critical metabolite of L. salivarius, could enter intestinal stem cells and induce high mitochondrial energy metabolism, ultimately promoting the activity of intestinal stem cells. These findings contribute to understanding the mechanism by which Lactobacillus regulate intestinal stem cell activity in chickens.
Article
Food Science & Technology
Fanqiang Meng, Xiaoyu Zhu, Haizhen Zhao, Ting Nie, Fengxia Lu, Zhaoxin Lu, Yingjian Lu
Summary: A novel class III bacteriocin gene, NX371, was identified and expressed from Lactobacillus acidophilus with significant antimicrobial activity against various foodborne pathogens. The study demonstrated that NX371 exhibited thermal and pH stability, effectively inhibiting the growth of pathogens in milk and cheese.
Article
Microbiology
Wei-Gang Xin, Xin-Dong Li, Yi-Cen Lin, Yu-Hang Jiang, Mei-Yu Xu, Qi-Lin Zhang, Feng Wang, Lian-Bing Lin
Summary: This study investigated the genomic characteristics of L. salivarius S01 strain isolated from the intestine of S. grahami and its impact on the host fish. The results indicated that this potential probiotic strain positively influenced the gut microbial diversity of S. grahami.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Multidisciplinary Sciences
R. Gacesa, A. Kurilshikov, A. Vich Vila, T. Sinha, M. A. Y. Klaassen, L. A. Bolte, S. Andreu-Sanchez, L. Chen, V. Collij, S. Hu, J. A. M. Dekens, V. C. Lenters, J. R. Bjork, J. C. Swarte, M. A. Swertz, B. H. Jansen, J. Gelderloos-Arends, S. Jankipersadsing, M. Hofker, R. C. H. Vermeulen, S. Sanna, H. J. M. Harmsen, C. Wijmenga, J. Fu, A. Zhernakova, R. K. Weersma
Summary: This study analyzed the gut microbiome of 8,208 individuals from the Netherlands and found that the microbiome is primarily shaped by the environment and cohabitation. Only about 6.6% of microbial taxa are heritable, while around 48.6% of taxa are significantly influenced by cohabitation. Additionally, the study identified numerous associations between the microbiome and health, diet, socioeconomic factors, and early-life and current exposome.
Article
Microbiology
Francesca Algieri, Nina Tanaskovic, Cindy Cardenas Rincon, Elisabetta Notario, Daniele Braga, Graziano Pesole, Roberto Rusconi, Giuseppe Penna, Maria Rescigno
Summary: The maintenance of intestinal barrier function is crucial for preventing diseases. The gut microbiota plays a key role in regulating the integrity of the intestinal barrier. This study demonstrates that a postbiotic called LP-PBF, derived from Lactobacillus paracasei CNCM I-5220, can restore tight junction morphology and protect against Salmonella typhimurium infection by interacting with the host cells and inhibiting biofilm formation. These findings suggest that LP-PBF could be a potential therapeutic option for diseases with impaired intestinal barrier function.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Microbiology
Roberto Vazquez-Munoz, Angela Thompson, Jordan T. Russell, Takanori Sobue, Yanjiao Zhou, Anna Dongari-Bagtzoglou
Summary: In this study, the interactions between Lactobacillus johnsonii and Candida albicans were investigated. The results showed that L. johnsonii exhibited inhibitory effects on C. albicans growth, both in planktonic and biofilm states. These effects were influenced by pH and nutrient availability, and could be attributed to the production of soluble metabolites with anticandidal activity.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Yu-Hang Jiang, Wei-Gang Xin, Lin-Yu Yang, Jian-Ping Ying, Zi-Shun Zhao, Lian-Bing Lin, Xiu-Zhang Li, Qi-Lin Zhang
Summary: A novel LAB bacteriocin LSX01 isolated from traditional fermented yogurt in Yunnan, China was found to possess antibacterial and antibiofilm activity against Staphylococcus aureus, suggesting its potential in improving dairy product safety.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Nutrition & Dietetics
Benjamin C. T. Bourrie, Andrew J. Forgie, Alexander Makarowski, Paul D. Cotter, Caroline Richard, Benjamin P. Willing
Summary: This study compared the effects of commercial kefir without traditional kefir organisms and pitched kefir containing traditional organisms on lipid levels, glucose homeostasis, and markers of endothelial function and inflammation. The findings showed that pitched kefir consumption led to reductions in LDL-C, ICAM-1, and VCAM-1, while commercial kefir consumption increased TNF-α levels.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2023)
Review
Gastroenterology & Hepatology
Susan Mills, Bo Yang, Graeme J. Smith, Catherine Stanton, R. Paul Ross
Summary: The colonization of Bifidobacterium in the neonatal gut highlights its significance to human health. Bifidobacterium longum is the most abundant species during early stages, but its levels decrease with age and in certain diseases. Research has revealed that B. longum produces bioactive molecules and can impact immune responses in various parts of the body. This review emphasizes the biological and clinical impacts of B. longum throughout different stages of human life, suggesting the need for further research and clinical trials to explore its potential in treating and preventing diseases.
Article
Gastroenterology & Hepatology
Daniel Merenstein, Bruno Pot, Gregory Leyer, Arthur C. Ouwehand, Geoffrey A. Preidis, Christopher A. Elkins, Colin Hill, Zachery T. Lewis, Andrea L. Shane, Niv Zmora, Mariya I. Petrova, Maria Carmen Collado, Lorenzo Morelli, Gina A. Montoya, Hania Szajewska, Daniel J. Tancredi, Mary Ellen Sanders
Summary: Probiotics are used by both healthy individuals and in clinical settings, but there are potential risks associated with their consumption. This has led to the need for concise recommendations on how to ensure the safe and effective use of new probiotic strains and products, especially in vulnerable populations.
Article
Microbiology
Ivan Sugrue, Daragh Hill, Paula M. O'Connor, Li Day, Catherine Stanton, Colin Hill, R. Paul Ross
Summary: This study describes a new variant of nisin, nisin E, produced by Streptococcus equinus strains isolated from sheep milk. The genome sequencing and analysis revealed similarities to nisin U, but with a unique rearrangement of the core peptide encoding gene. Nisin E showed antimicrobial activity against Lactobacillus, Bacillus, and Clostridiodes, and was immune to nisin U. The discovery of nisin E suggests its central role in the competitive nature of S. equinus.
Review
Food Science & Technology
Eleni Kamilari, Catherine Stanton, F. Jerry Reen, R. Paul Ross
Summary: This review highlights the biotechnological importance of the filamentous yeast-like fungus Geotrichum candidum, which is widely used as a starter in the dairy industry. The study found that aside from its role in the dairy and brewing industries, G. candidum has potential as a probiotic nutritional supplement in fish. Additionally, this species produces various biotechnologically important enzymes, antimicrobial compounds, and has bioremediation capabilities.
Review
Multidisciplinary Sciences
Jose Guilherme Prado Martin, Paul D. Cotter
Summary: The microbial diversity of artisanal cheeses, particularly the detection and identification of fungi on cheese rinds, has been extensively studied. The composition and abundance of fungi on cheese surfaces can greatly impact sensory qualities, defects, ripening, and mycotoxin risks. This review critically discusses the influence of fungi on artisanal cheese quality and the potential for producers to exploit their presence for innovative products with greater added value. These discussions are important for the future commercialization and regulation of artisanal cheeses with high abundance of molds.
Article
Microbiology
Neda Nezam-Abadi, Christopher J. R. Turkington, Lorraine A. Draper, Andrey N. Shkoporov, R. Paul Ross, Colin Hill
Summary: Here, we present the draft genome sequence of Legionella pneumophila subsp. pneumophila strain DSM 25199, a serogroup 1 strain with a genome size of 3,426,844 bp. The assembly consists of 24 contigs with an N-50 of 300,843 bp.
MICROBIOLOGY RESOURCE ANNOUNCEMENTS
(2023)
Article
Food Science & Technology
Benjamin C. T. Bourrie, Natalie Diether, Ryan P. Dias, Seo Lin Nam, A. Paulina de la Mata, Andrew J. Forgie, Gautam Gaur, James J. Harynuk, Michael Ganzle, Paul D. Cotter, Benjamin P. Willing
Summary: Kefir fermentation using kefir grains and commercial fermentation with planktonic cultures produce kefir with different metabolite compositions. The presence of lactobacilli in the fermentation greatly impacts the production of organic acids, while the absence of yeast has minimal effect. This study highlights the importance of microbial composition in kefir fermentation.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Food Science & Technology
Adrian Alvarez-Molina, Jose F. Cobo-Diaz, Elena A. Alexa, Fiona Crispie, Miguel Prieto, Mercedes Lopez, Paul D. Cotter, Avelino Alvarez-Ordonez
Summary: In recent years, advances in high throughput sequencing technologies have opened up new possibilities for environmental monitoring in the food processing industry. This study used whole metagenome sequencing to assess the microbiome and resistome of food processing environments from slaughterhouses, dairy processing plants, and meat processing plants. The results showed that slaughterhouses had more diverse microbiomes and resistomes, while dairy processing plants had the highest variability. Different predominant bacterial genera were found in each industry type. The study also identified the most abundant antimicrobial resistance genes, which were associated with resistance to aminoglycosides, tetracyclines, and quaternary ammonium compounds. The findings have important implications for food safety management systems.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Multidisciplinary Sciences
Liam H. Walsh, Mairead Coakley, Aaron M. Walsh, Fiona Crispie, Paul W. O'Toole, Paul D. Cotter
Summary: A comprehensive metagenomics investigation of milk kefir from different countries revealed the core and non-core components of its microbial community. The dominant species in each kefir were identified, along with associated metabolic pathways. This knowledge can assist in creating tailored kefir communities for various applications, and ensure the microbial composition of kefir products reflects the traditional beverage.
Article
Obstetrics & Gynecology
Rebecca L. Moore, Conor Feehily, Sarah Louise Killeen, Cara A. Yelverton, Aisling A. Geraghty, Calum J. Walsh, Ian J. O'Neill, Ida Busch Nielsan, Elaine M. Lawton, Rocio Sanchez-Gallardo, Sai Ravi Chandra Nori, Fergus Shanahan, Eileen F. Murphy, Douwe Van Sinderen, Paul D. Cotter, Fionnuala M. McAuliffe
Summary: This study aimed to investigate if maternal probiotic supplementation in pregnancy can affect the infant gut microbiome. The results showed that direct mother-to-infant strain transfer of the supplemented probiotic occurred, albeit infrequently. This study highlights the potential for maternal supplementation to introduce microbial strains into the infant microbiome.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2023)
Review
Microbiology
Des Field, Miguel Fernandez de Ullivarri, R. Paul Ross, Colin Hill
Summary: Nisin, a highly post-translationally modified peptide, has been extensively studied over the past 100 years. While it has been used successfully as a food preservative, its potent activity against multidrug resistant microbes and potential for therapeutic use in treating bacterial infections has shifted the focus of research towards its biomedical applications. Recent developments have shed light on the biosynthesis, cellular location, and genetic regulation of nisin, and there is growing interest in its potential role in influencing the microbiome and in bioengineering novel variants for biomedical applications.
FEMS MICROBIOLOGY REVIEWS
(2023)
Article
Nutrition & Dietetics
Xinqi Chen, Yang Chen, Catherine Stanton, Reynolds Paul Ross, Jianxin Zhao, Wei Chen, Bo Yang
Summary: This study aimed to investigate the dose-response effect of Bifidobacterium breve CCFM683 on relieving psoriasis and its underlying patterns. Specifically, the expression of keratin 16, keratin 17, and involucrin were substantially decreased by specific doses of the probiotic. Moreover, the gut microbiota in mice treated with the probiotic was rebalanced and the concentrations of colonic bile acids were positively correlated with the effectiveness of the strain in relieving psoriasis.
Article
Food Science & Technology
Kexue Chen, Xingya Zhou, Jianxin Zhao, R. Paul Ross, Catherine Stanton, Wei Chen, Bo Yang
Summary: This study explores the genetic diversity and functional gene features of L. johnsonii through comparative genomic analysis. The results show that L. johnsonii can be classified into two phylogenetic clusters, with differences in carbohydrate utilization genes, bacteriocin operon, extracellular polysaccharide gene cluster, and bile salt hydrolase encoding genes between the clusters.