Mechanisms of lymphatic metastasis

Non-invasive dynamic near-infrared imaging and quantification of vascular leakage in vivo

(2013) Steven T. Proulx et al.   ANGIOGENESIS

Use of a PEG-conjugated bright near-infrared dye for functional imaging of rerouting of tumor lymphatic drainage after sentinel lymph node metastasis

(2013) Steven T. Proulx et al.   BIOMATERIALS

Interleukin-7 is produced by afferent lymphatic vessels and supports lymphatic drainage

(2013) M. Iolyeva et al.   BLOOD

Dynamics of lymphatic regeneration and flow patterns after lymph node dissection

(2013) Katrin S. Blum et al.   BREAST CANCER RESEARCH AND TREATMENT

VEGF-C and VEGF-D Blockade Inhibits Inflammatory Skin Carcinogenesis

(2013) A. K. Alitalo et al.   CANCER RESEARCH

Mechanical forces in lymphatic vascular development and disease

(2013) Lara Planas-Paz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Molecular mechanisms and imaging of lymphatic metastasis

(2013) Steven T. Proulx et al.   EXPERIMENTAL CELL RESEARCH

Expansion of the lymphatic vasculature in cancer and inflammation: New opportunities for in vivo imaging and drug delivery

(2013) Steven T. Proulx et al.   JOURNAL OF CONTROLLED RELEASE

Tumor cell entry into the lymph node is controlled by CCL1 chemokine expressed by lymph node lymphatic sinuses

(2013) Suvendu Das et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Anti-lymphangiogenesis effects of a specific anti-interleukin 7 receptor antibody in lung cancer model in vivo

(2013) Ming Jian et al.   MOLECULAR CARCINOGENESIS

Inhibition of VEGF-C Modulates Distal Lymphatic Remodeling and Secondary Metastasis

(2013) Alvin Gogineni et al.   PLoS One

Evidence for the interaction of fibroblast growth factor-2 with the lymphatic endothelial cell marker LYVE-1

(2012) N. Platonova et al.   BLOOD

Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells

(2012) E. F. Tewalt et al.   BLOOD

Sphingosine-1-Phosphate Produced by Sphingosine Kinase 1 Promotes Breast Cancer Progression by Stimulating Angiogenesis and Lymphangiogenesis

(2012) M. Nagahashi et al.   CANCER RESEARCH

Adrenomedullin gene dosage correlates with tumor and lymph node lymphangiogenesis

(2012) Natalie O. Karpinich et al.   FASEB JOURNAL

Effects of Angiopoietin-2-Blocking Antibody on Endothelial Cell–Cell Junctions and Lung Metastasis

(2012) Tanja Holopainen et al.   JNCI-Journal of the National Cancer Institute

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

Phenotype-based high-content chemical library screening identifies statins as inhibitors of in vivo lymphangiogenesis

(2012) M. M. P. Schulz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

VEGF-C Promotes Immune Tolerance in B16 Melanomas and Cross-Presentation of Tumor Antigen by Lymph Node Lymphatics

(2012) Amanda W. Lund et al.   Cell Reports

Lymphatic endothelial cells - key players in regulation of tolerance and immunity

(2012) Eric F. Tewalt et al.   Frontiers in Immunology

Sentinel Node Mapping for Breast Cancer: Current Situation

(2012) Sergi Vidal-Sicart et al.   Journal of Oncology

Inflammation-Induced Lymph Node Lymphangiogenesis Is Reversible

(2011) Viviane Mumprecht et al.   AMERICAN JOURNAL OF PATHOLOGY

Sentinel Lymph Node Pressure in Breast Cancer

(2011) S. David Nathanson et al.   ANNALS OF SURGICAL ONCOLOGY

Vascular endothelial growth factor C attenuates joint damage in chronic inflammatory arthritis by accelerating local lymphatic drainage in mice

(2011) Quan Zhou et al.   ARTHRITIS AND RHEUMATISM

An important role of lymphatic vessel activation in limiting acute inflammation

(2011) R. Huggenberger et al.   BLOOD

Exosomes Released by Melanoma Cells Prepare Sentinel Lymph Nodes for Tumor Metastasis

(2011) J. L. Hood et al.   CANCER RESEARCH

Mechanoinduction of lymph vessel expansion

(2011) Lara Planas-Paz et al.   EMBO JOURNAL

Do all roads lead to Rome? Routes to metastasis development

(2011) Jonathan P. Sleeman et al.   INTERNATIONAL JOURNAL OF CANCER

Lipoxygenase mediates invasion of intrametastatic lymphatic vessels and propagates lymph node metastasis of human mammary carcinoma xenografts in mouse

(2011) Dontscho Kerjaschki et al.   JOURNAL OF CLINICAL INVESTIGATION

Tissue Fluid Pressure and Flow during Pneumatic Compression in Lymphedema of Lower Limbs

(2011) Waldemar L Olszewski et al.   Lymphatic Research and Biology

Interaction of tumor cells and lymphatic vessels in cancer progression

(2011) A Alitalo et al.   ONCOGENE

Photodynamic Ablation of Lymphatic Vessels and Intralymphatic Cancer Cells Prevents Metastasis

(2011) T. Tammela et al.   Science Translational Medicine

In vivo Imaging of Inflammation- and Tumor-Induced Lymph Node Lymphangiogenesis by Immuno-Positron Emission Tomography

(2010) V. Mumprecht et al.   CANCER RESEARCH

CXCR4 Signaling Regulates Metastasis of Chemoresistant Melanoma Cells by a Lymphatic Metastatic Niche

(2010) M. Kim et al.   CANCER RESEARCH

Quantitative Imaging of Lymphatic Function with Liposomal Indocyanine Green

(2010) S. T. Proulx et al.   CANCER RESEARCH

Lymphangiogenesis: Molecular Mechanisms and Future Promise

(2010) Tuomas Tammela et al.   CELL

Transmural Flow Modulates Cell and Fluid Transport Functions of Lymphatic Endothelium

(2010) Dimana O. Miteva et al.   CIRCULATION RESEARCH

Lymph node–resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation

(2010) Jarish N. Cohen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Stimulation of lymphangiogenesis via VEGFR-3 inhibits chronic skin inflammation

(2010) Reto Huggenberger et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Breast Cancer Prognosis and Occult Lymph Node Metastases, Isolated Tumor Cells, and Micrometastases

(2010) M. de Boer et al.   JNCI-Journal of the National Cancer Institute

Induction of Lymphoidlike Stroma and Immune Escape by Tumors That Express the Chemokine CCL21

(2010) J. D. Shields et al.   SCIENCE

Nodal Lymphangiogenesis and Metastasis

(2009) Satoshi Hirakawa et al.   AMERICAN JOURNAL OF PATHOLOGY

An in vivo chemical library screen in Xenopus tadpoles reveals novel pathways involved in angiogenesis and lymphangiogenesis

(2009) R. E. Kalin et al.   BLOOD

Lymphangiogenesis and cancer metastasis

(2009) Viviane Mumprecht et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Visualization of Tumor Blockage and Rerouting of Lymphatic Drainage in Penile Cancer Patients by Use of SPECT/CT

(2009) J. A.P. Leijte et al.   JOURNAL OF NUCLEAR MEDICINE

Mechanisms of lymphatic metastasis in human colorectal adenocarcinoma

(2009) Daniel Royston et al.   JOURNAL OF PATHOLOGY

A Novel Gene Expression Profile in Lymphatics Associated with Tumor Growth and Nodal Metastasis

(2008) S. Clasper et al.   CANCER RESEARCH

Identification of the surface-accessible, lineage-specific vascular proteome by two-dimensional peptide mapping

(2008) Christoph Roesli et al.   FASEB JOURNAL

Lymphatic invasion in cutaneous melanoma is associated with sentinel lymph node metastasis

(2008) Katie Doeden et al.   JOURNAL OF CUTANEOUS PATHOLOGY

Activation of the VEGFR-3 Pathway by VEGF-C Attenuates UVB-Induced Edema Formation and Skin Inflammation by Promoting Lymphangiogenesis

(2008) Kentaro Kajiya et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Lymphatic System in Health and Disease

(2008) Leah N. Cueni et al.   Lymphatic Research and Biology

Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation

(2008) Tuomas Tammela et al.   NATURE