Neural peptidase endothelin-converting enzyme 1 regulates endothelin 1–induced pruritus

The Epithelial Cell-Derived Atopic Dermatitis Cytokine TSLP Activates Neurons to Induce Itch

(2013) Sarah R. Wilson et al.   CELL

A sensory neuron–expressed IL-31 receptor mediates T helper cell–dependent itch: Involvement of TRPV1 and TRPA1

(2013) Ferda Cevikbas et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Neural processing of itch

(2013) Tasuku Akiyama et al.   NEUROSCIENCE

Evaluation and management of a patient with chronic pruritus

(2012) Martin Steinhoff et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Endothelin-1 induces itch and pain in the mouse cheek model

(2012) Lenyta Oliveira Gomes et al.   LIFE SCIENCES

Protein phosphatase 2A mediates resensitization of the neurokinin 1 receptor

(2011) Jane E. Murphy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Pain and itch: insights into the neural circuits of aversive somatosensation in health and disease

(2011) Sarah E Ross   CURRENT OPINION IN NEUROBIOLOGY

Molecular signaling of pruritus induced by endothelin-1 in mice

(2011) Jiexian Liang et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Endothelin-converting enzyme-1 regulates trafficking and signalling of the neurokinin 1 receptor in endosomes of myenteric neurones

(2011) Juan-Carlos Pelayo et al.   JOURNAL OF PHYSIOLOGY-LONDON

TRPA1 is required for histamine-independent, Mas-related G protein–coupled receptor–mediated itch

(2011) Sarah R Wilson et al.   NATURE NEUROSCIENCE

Role of transient receptor potential ankyrin subfamily member 1 in pruritus induced by endothelin-1

(2011) Jiexian Liang et al.   NEUROSCIENCE LETTERS

Pathophysiology and therapy of pruritus in allergic and atopic diseases

(2010) J. Buddenkotte et al.   ALLERGY

Endothelin-converting enzyme 1 promotes re-sensitization of neurokinin 1 receptor-dependent neurogenic inflammation

(2009) F Cattaruzza et al.   BRITISH JOURNAL OF PHARMACOLOGY

Sensory Neuron-Specific GPCR Mrgprs Are Itch Receptors Mediating Chloroquine-Induced Pruritus

(2009) Qin Liu et al.   CELL

Endosomal Endothelin-converting Enzyme-1

(2009) Graeme S. Cottrell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TLR2 and TLR4 agonists induce production of the vasoactive peptide endothelin-1 by human dendritic cells

(2009) Rolf Spirig et al.   MOLECULAR IMMUNOLOGY

Endothelin evokes distinct calcium transients in neuronal and non-neuronal cells of rat olfactory mucosa primary cultures

(2009) E. Gouadon et al.   NEUROSCIENCE

TRPV1-expressing primary afferents generate behavioral responses to pruritogens via multiple mechanisms

(2009) N. Imamachi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endosomes: A legitimate platform for the signaling train

(2009) J. E. Murphy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for the role of neurogenic inflammation components in trypsin-elicited scratching behaviour in mice

(2008) R Costa et al.   BRITISH JOURNAL OF PHARMACOLOGY

Endothelin-Converting Enzyme-1 Degrades Internalized Somatostatin-14

(2008) Dirk Roosterman et al.   ENDOCRINOLOGY

Intracellular degradation of somatostatin-14 following somatostatin-receptor 3-mediated endocytosis in rat insulinoma cells

(2008) Dirk Roosterman et al.   FEBS Journal

Endothelin-1-induced pain and hyperalgesia: A review of pathophysiology, clinical manifestations and future therapeutic options

(2008) Guy Hans et al.   NEUROPEPTIDES

Behavioral differentiation between itch and pain in mouse

(2008) Steven G. Shimada et al.   PAIN

Characterization of a Hapten-Induced, Murine Model with Multiple Features of Atopic Dermatitis: Structural, Immunologic, and Biochemical Changes following Single Versus Multiple Oxazolone Challenges

(2007) Mao-Qiang Man et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY