Cis-element mutated in GATA2-dependent immunodeficiency governs hematopoiesis and vascular integrity

Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies

(2012) E. H. Bresnick et al.   NUCLEIC ACIDS RESEARCH

Context-dependent function of "GATA switch" sites in vivo

(2011) J. W. Snow et al.   BLOOD

Single-lineage transcriptome analysis reveals key regulatory pathways in primitive erythroid progenitors in the mouse embryo

(2011) J. Isern et al.   BLOOD

Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency

(2011) R. E. Dickinson et al.   BLOOD

Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome

(2011) A. P. Hsu et al.   BLOOD

Epigenetically coordinated GATA2 binding is necessary for endothelium-specificendomucinexpression

(2011) Yasuharu Kanki et al.   EMBO JOURNAL

Myelodysplasia in autosomal dominant and sporadic monocytopenia immunodeficiency syndrome: diagnostic features and clinical implications

(2011) K. R. Calvo et al.   HAEMATOLOGICA

Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome)

(2011) Pia Ostergaard et al.   NATURE GENETICS

Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia

(2011) Christopher N Hahn et al.   NATURE GENETICS

Genetic framework for GATA factor function in vascular biology

(2011) A. K. Linnemann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Integrin Co-activator Kindlin-3 Is Expressed and Functional in a Non-hematopoietic Cell, the Endothelial Cell

(2010) Katarzyna Bialkowska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GATA Switches as Developmental Drivers

(2010) Emery H. Bresnick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Single cis Element Maintains Repression of the Key Developmental Regulator Gata2

(2010) Jonathan W. Snow et al.   PLoS Genetics

High GATA-2 expression inhibits human hematopoietic stem and progenitor cell function by effects on cell cycle

(2009) A. J. Tipping et al.   BLOOD

Autosomal dominant and sporadic monocytopenia with susceptibility to mycobacteria, fungi, papillomaviruses, and myelodysplasia

(2009) D. C. Vinh et al.   BLOOD

GATA-2 L359 V mutation is exclusively associated with CML progression but not other hematological malignancies and GATA-2 P250A is a novel single nucleotide polymorphism

(2009) Su-Jiang Zhang et al.   LEUKEMIA RESEARCH

Discovering Hematopoietic Mechanisms through Genome-wide Analysis of GATA Factor Chromatin Occupancy

(2009) Tohru Fujiwara et al.   MOLECULAR CELL

A mechanosensitive transcriptional mechanism that controls angiogenesis

(2009) Akiko Mammoto et al.   NATURE

CD150- cells are transiently reconstituting multipotent progenitors with little or no stem cell activity

(2008) M. J. Kiel et al.   BLOOD

Oncogenic Kras-induced leukemogeneis: hematopoietic stem cells as the initial target and lineage-specific progenitors as the potential targets for final leukemic transformation

(2008) J. Zhang et al.   BLOOD

Defining the Functional Boundaries of theGata2Locus by Rescue with a Linked Bacterial Artificial Chromosome Transgene

(2008) William Brandt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Hallmarks of Endogenous Chromatin Complexes Containing Master Regulators of Hematopoiesis

(2008) R. J. Wozniak et al.   MOLECULAR AND CELLULAR BIOLOGY

Kindlin-3 is essential for integrin activation and platelet aggregation

(2008) Markus Moser et al.   NATURE MEDICINE

Gain-of-function mutation of GATA-2 in acute myeloid transformation of chronic myeloid leukemia

(2008) S.-J. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA