标题
Molecular pathogenesis of chronic lymphocytic leukemia
作者
关键词
-
出版物
JOURNAL OF CLINICAL INVESTIGATION
Volume 122, Issue 10, Pages 3432-3438
出版商
American Society for Clinical Investigation
发表日期
2012-10-01
DOI
10.1172/jci64101
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Risk categories and refractory CLL in the era of chemoimmunotherapy
- (2012) T. Zenz et al. BLOOD
- Monoclonal B-cell lymphocytosis: right track or red herring?
- (2012) P. Ghia et al. BLOOD
- Stereotyped B-cell receptors in one-third of chronic lymphocytic leukemia: a molecular classification with implications for targeted therapies
- (2012) A. Agathangelidis et al. BLOOD
- The IGHV1-69/IGHJ3 recombinations of unmutated CLL are distinct from those of normal B cells
- (2012) F. Forconi et al. BLOOD
- Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukemia
- (2012) D. Rossi et al. BLOOD
- The B-cell receptor signaling pathway as a therapeutic target in CLL
- (2012) J. A. Woyach et al. BLOOD
- Different impact of NOTCH1 and SF3B1 mutations on the risk of chronic lymphocytic leukemia transformation to Richter syndrome
- (2012) Davide Rossi et al. BRITISH JOURNAL OF HAEMATOLOGY
- Analysis ofSF3B1mutations in monoclonal B-cell lymphocytosis
- (2012) Mariangela Greco et al. HEMATOLOGICAL ONCOLOGY
- ERIC recommendations on TP53 mutation analysis in chronic lymphocytic leukemia
- (2012) S Pospisilova et al. LEUKEMIA
- The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
- (2012) Jinghui Zhang et al. NATURE
- Functional dissection of the chromosome 13q14 tumor-suppressor locus using transgenic mouse lines
- (2011) M. Lia et al. BLOOD
- NOTCH1 mutations in CLL associated with trisomy 12
- (2011) V. Balatti et al. BLOOD
- Alteration of BIRC3 and multiple other NF- B pathway genes in splenic marginal zone lymphoma
- (2011) D. Rossi et al. BLOOD
- Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness
- (2011) D. Rossi et al. BLOOD
- Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia
- (2011) D. Rossi et al. BLOOD
- The genetics of Richter syndrome reveals disease heterogeneity and predicts survival after transformation
- (2011) D. Rossi et al. BLOOD
- Self-Renewing Hematopoietic Stem Cell Is the Primary Target in Pathogenesis of Human Chronic Lymphocytic Leukemia
- (2011) Yoshikane Kikushige et al. CANCER CELL
- Predictive markers and driving factors behind Richter syndrome development
- (2011) Marco Fangazio et al. Expert Review of Anticancer Therapy
- Therapeutic potential of Notch inhibition in T-cell acute lymphoblastic leukemia: rationale, caveats and promises
- (2011) Leonor M Sarmento et al. Expert Review of Anticancer Therapy
- ATM and chronic lymphocytic leukemia: mutations, and not only deletions, matter
- (2011) D. Rossi et al. HAEMATOLOGICA
- ATM gene alterations in chronic lymphocytic leukemia patients induce a distinct gene expression profile and predict disease progression
- (2011) A. Guarini et al. HAEMATOLOGICA
- ATM germline heterozygosity does not play a role in chronic lymphocytic leukemia initiation but influences rapid disease progression through loss of the remaining ATM allele
- (2011) A. Skowronska et al. HAEMATOLOGICA
- Analysis of NOTCH1 mutations in monoclonal B-cell lymphocytosis
- (2011) S. Rasi et al. HAEMATOLOGICA
- BCR and TLR signaling pathways are recurrently targeted by genetic changes in splenic marginal zone lymphomas
- (2011) Q. Yan et al. HAEMATOLOGICA
- NOTCH1 mutations in +12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of +12 CLL
- (2011) I. Del Giudice et al. HAEMATOLOGICA
- Molecular history of Richter syndrome: origin from a cell already present at the time of chronic lymphocytic leukemia diagnosis
- (2011) Davide Rossi et al. INTERNATIONAL JOURNAL OF CANCER
- Association of a MicroRNA/TP53 Feedback Circuitry With Pathogenesis and Outcome of B-Cell Chronic Lymphocytic Leukemia
- (2011) Muller Fabbri JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Mutational Status of theTP53Gene As a Predictor of Response and Survival in Patients With Chronic Lymphocytic Leukemia: Results From the LRF CLL4 Trial
- (2011) David Gonzalez et al. JOURNAL OF CLINICAL ONCOLOGY
- Analysis of the chronic lymphocytic leukemia coding genome: role ofNOTCH1mutational activation
- (2011) Giulia Fabbri et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Initial genome sequencing and analysis of multiple myeloma
- (2011) Michael A. Chapman et al. NATURE
- Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
- (2011) Xose S. Puente et al. NATURE
- Analysis of the coding genome of diffuse large B-cell lymphoma
- (2011) Laura Pasqualucci et al. NATURE GENETICS
- Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
- (2011) Víctor Quesada et al. NATURE GENETICS
- Spliceosome mutations in hematopoietic malignancies
- (2011) Christopher N Hahn et al. NATURE GENETICS
- SF3B1and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia
- (2011) Lili Wang et al. NEW ENGLAND JOURNAL OF MEDICINE
- Chronic lymphocytic leukemia: the pathologist's view of lymph node microenvironment
- (2011) Maurilio Ponzoni et al. SEMINARS IN DIAGNOSTIC PATHOLOGY
- Deconstructing p53 transcriptional networks in tumor suppression
- (2011) Kathryn T. Bieging et al. TRENDS IN CELL BIOLOGY
- Cellular origin(s) of chronic lymphocytic leukemia: cautionary notes and additional considerations and possibilities
- (2010) N. Chiorazzi et al. BLOOD
- Many chronic lymphocytic leukemia antibodies recognize apoptotic cells with exposed nonmuscle myosin heavy chain IIA: implications for patient outcome and cell of origin
- (2010) C. C. Chu et al. BLOOD
- A variant of the LRP4 gene affects the risk of chronic lymphocytic leukaemia transformation to Richter syndrome
- (2010) Silvia Rasi et al. BRITISH JOURNAL OF HAEMATOLOGY
- NOTCH1 PEST domain mutation is an adverse prognostic factor in B-CLL
- (2010) Paolo Sportoletti et al. BRITISH JOURNAL OF HAEMATOLOGY
- The DLEU2/miR-15a/16-1 Cluster Controls B Cell Proliferation and Its Deletion Leads to Chronic Lymphocytic Leukemia
- (2010) Ulf Klein et al. CANCER CELL
- TP53Mutation and Survival in Chronic Lymphocytic Leukemia
- (2010) Thorsten Zenz et al. JOURNAL OF CLINICAL ONCOLOGY
- Addition of rituximab to fludarabine and cyclophosphamide in patients with chronic lymphocytic leukaemia: a randomised, open-label, phase 3 trial
- (2010) M Hallek et al. LANCET
- Oncogenically active MYD88 mutations in human lymphoma
- (2010) Vu N. Ngo et al. NATURE
- Advances in understanding cancer genomes through second-generation sequencing
- (2010) Matthew Meyerson et al. NATURE REVIEWS GENETICS
- Regulation and Function of NF-κB Transcription Factors in the Immune System
- (2009) Sivakumar Vallabhapurapu et al. Annual Review of Immunology
- Monoallelic and biallelic inactivation of TP53 gene in chronic lymphocytic leukemia: selection, impact on survival, and response to DNA damage
- (2009) J. Malcikova et al. BLOOD
- The microenvironment in mature B-cell malignancies: a target for new treatment strategies
- (2009) J. A. Burger et al. BLOOD
- The prognosis of clinical monoclonal B cell lymphocytosis differs from prognosis of Rai 0 chronic lymphocytic leukaemia and is recapitulated by biological risk factors
- (2009) Davide Rossi et al. BRITISH JOURNAL OF HAEMATOLOGY
- miR-15a and miR-16 Are Implicated in Cell Cycle Regulation in a Rb-Dependent Manner and Are Frequently Deleted or Down-regulated in Non–Small Cell Lung Cancer
- (2009) Nora Bandi et al. CANCER RESEARCH
- The Spliceosome: Design Principles of a Dynamic RNP Machine
- (2009) Markus C. Wahl et al. CELL
- Stereotyped B-Cell Receptor Is an Independent Risk Factor of Chronic Lymphocytic Leukemia Transformation to Richter Syndrome
- (2009) D. Rossi et al. CLINICAL CANCER RESEARCH
- The Prognostic Value of TP53 Mutations in Chronic Lymphocytic Leukemia Is Independent of Del17p13: Implications for Overall Survival and Chemorefractoriness
- (2009) D. Rossi et al. CLINICAL CANCER RESEARCH
- Richter syndrome: molecular insights and clinical perspectives
- (2009) Davide Rossi et al. HEMATOLOGICAL ONCOLOGY
- Brief Report: Natural History of Individuals With Clinically Recognized Monoclonal B-Cell Lymphocytosis Compared With Patients With Rai 0 Chronic Lymphocytic Leukemia
- (2009) Tait D. Shanafelt et al. JOURNAL OF CLINICAL ONCOLOGY
- Telomere length is an independent predictor of survival, treatment requirement and Richter's syndrome transformation in chronic lymphocytic leukemia
- (2009) D Rossi et al. LEUKEMIA
- B-Cell Clones as Early Markers for Chronic Lymphocytic Leukemia
- (2009) Ola Landgren et al. NEW ENGLAND JOURNAL OF MEDICINE
- Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome
- (2009) Elaine R. Mardis et al. NEW ENGLAND JOURNAL OF MEDICINE
- Monoclonal B-cell lymphocytosis
- (2009) A. C. Rawstron Hematology-American Society of Hematology Education Program
- The role of NOTCH1 signaling in T-ALL
- (2009) A. A. Ferrando Hematology-American Society of Hematology Education Program
- CD38 gene polymorphism and chronic lymphocytic leukemia: a role in transformation to Richter syndrome?
- (2008) S. Aydin et al. BLOOD
- BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgVH unmutated chronic lymphocytic leukemia (CLL) cells
- (2008) A. Guarini et al. BLOOD
- The c-myb proto-oncogene and microRNA-15a comprise an active autoregulatory feedback loop in human hematopoietic cells
- (2008) H. Zhao et al. BLOOD
- Chronic lymphocytic leukemia antibodies with a common stereotypic rearrangement recognize nonmuscle myosin heavy chain IIA
- (2008) C. C. Chu et al. BLOOD
- Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: results from a detailed genetic characterization with long-term follow-up
- (2008) T. Zenz et al. BLOOD
- Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines
- (2008) M. Hallek et al. BLOOD
- Biological and clinical risk factors of chronic lymphocytic leukaemia transformation to Richter syndrome
- (2008) Davide Rossi et al. BRITISH JOURNAL OF HAEMATOLOGY
- Molecular and clinical features of chronic lymphocytic leukaemia with stereotyped B cell receptors: results from an Italian multicentre study
- (2008) Riccardo Bomben et al. BRITISH JOURNAL OF HAEMATOLOGY
- The detection of TP53 mutations in chronic lymphocytic leukemia independently predicts rapid disease progression and is highly correlated with a complex aberrant karyotype
- (2008) F Dicker et al. LEUKEMIA
- Monoclonal B-Cell Lymphocytosis and Chronic Lymphocytic Leukemia
- (2008) Andy C. Rawstron et al. NEW ENGLAND JOURNAL OF MEDICINE
- miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes
- (2008) Q. Liu et al. NUCLEIC ACIDS RESEARCH
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