Conditional Gata2 inactivation results in HSC loss and lymphatic mispatterning

GATA-3 regulates hematopoietic stem cell maintenance and cell-cycle entry

(2012) C.-J. Ku et al.   BLOOD

GATA-2 anomaly and clinical phenotype of a sporadic case of lymphedema, dendritic cell, monocyte, B- and NK-cell (DCML) deficiency, and myelodysplasia

(2012) Hiroyuki Ishida et al.   EUROPEAN JOURNAL OF PEDIATRICS

Three-dimensional imaging of whole midgestation murine embryos shows an intravascular localization for all hematopoietic clusters

(2011) T. Yokomizo et al.   BLOOD

Loss-of-function germline GATA2 mutations in patients with MDS/AML or MonoMAC syndrome and primary lymphedema reveal a key role for GATA2 in the lymphatic vasculature

(2011) J. Kazenwadel et al.   BLOOD

Context-dependent function of "GATA switch" sites in vivo

(2011) J. W. Snow et al.   BLOOD

Sox17 expression confers self-renewal potential and fetal stem cell characteristics upon adult hematopoietic progenitors

(2011) S. He et al.   GENES & DEVELOPMENT

Lymphatic vascular morphogenesis in development, physiology, and disease

(2011) Stefan Schulte-Merker et al.   JOURNAL OF CELL BIOLOGY

Gata2 Is Required for Migration and Differentiation of Retinorecipient Neurons in the Superior Colliculus

(2011) R. T. Willett et al.   JOURNAL OF NEUROSCIENCE

Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome)

(2011) Pia Ostergaard et al.   NATURE GENETICS

The Transcriptional Control of Lymphatic Vascular Development

(2011) Mathias Francois et al.   PHYSIOLOGY

Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation

(2010) P. Uhrin et al.   BLOOD

Distinct Hematopoietic Stem Cell Subtypes Are Differentially Regulated by TGF-β1

(2010) Grant A. Challen et al.   Cell Stem Cell

Platelets Play an Essential Role in Separating the Blood and Lymphatic Vasculatures During Embryonic Angiogenesis

(2010) Laura Carramolino et al.   CIRCULATION RESEARCH

Reprogramming adult hematopoietic cells

(2010) Shin Kaneko et al.   CURRENT OPINION IN HEMATOLOGY

GATA Switches as Developmental Drivers

(2010) Emery H. Bresnick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Single cis Element Maintains Repression of the Key Developmental Regulator Gata2

(2010) Jonathan W. Snow et al.   PLoS Genetics

GATA2-dependent and region-specific regulation ofGata2transcription in the mouse midbrain

(2009) Daisuke Nozawa et al.   GENES TO CELLS

GATA-3 is required for early T lineage progenitor development

(2009) Tomonori Hosoya et al.   JOURNAL OF EXPERIMENTAL MEDICINE

GATA-2 regulates granulocyte-macrophage progenitor cell function

(2008) N. P. Rodrigues et al.   BLOOD

Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

(2008) Anne Wilson et al.   CELL

Fate Tracing Reveals the Endothelial Origin of Hematopoietic Stem Cells

(2008) Ann C. Zovein et al.   Cell Stem Cell

Phospholipase C 2 is necessary for separation of blood and lymphatic vasculature in mice

(2008) H. Ichise et al.   DEVELOPMENT

Reduced BMP4 abundance in Gata2 hypomorphic mutant mice result in uropathies resembling human CAKUT

(2008) Tomofumi Hoshino et al.   GENES TO CELLS

Defining the Functional Boundaries of theGata2Locus by Rescue with a Linked Bacterial Artificial Chromosome Transgene

(2008) William Brandt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY