The Transcriptional Control of Lymphatic Vascular Development

Role of Delta-like-4/Notch in the Formation and Wiring of the Lymphatic Network in Zebrafish

(2010) Ilse Geudens et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Prox1 expression is negatively regulated by miR-181 in endothelial cells

(2010) J. Kazenwadel et al.   BLOOD

An exquisite cross-control mechanism among endothelial cell fate regulators directs the plasticity and heterogeneity of lymphatic endothelial cells

(2010) J. Kang et al.   BLOOD

Embryonic vascular endothelial cells are malleable to reprogramming via Prox1 to a lymphatic gene signature

(2010) Harold Kim et al.   BMC DEVELOPMENTAL BIOLOGY

Lymphangiogenesis: Molecular Mechanisms and Future Promise

(2010) Tuomas Tammela et al.   CELL

An RNAi Screen Identifies Msi2 and Prox1 as Having Opposite Roles in the Regulation of Hematopoietic Stem Cell Activity

(2010) Kristin J. Hope et al.   Cell Stem Cell

Arteries provide essential guidance cues for lymphatic endothelial cells in the zebrafish trunk

(2010) J. Bussmann et al.   DEVELOPMENT

Endothelial cell plasticity: how to become and remain a lymphatic endothelial cell

(2010) G. Oliver et al.   DEVELOPMENT

The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells

(2010) R. S. Srinivasan et al.   GENES & DEVELOPMENT

Tbx1 regulatesVegfr3and is required for lymphatic vessel development

(2010) Li Chen et al.   JOURNAL OF CELL BIOLOGY

Neuropilin-2 mediates VEGF-C–induced lymphatic sprouting together with VEGFR3

(2010) Yunling Xu et al.   JOURNAL OF CELL BIOLOGY

Direct transcriptional regulation of neuropilin-2 by COUP-TFII modulates multiple steps in murine lymphatic vessel development

(2010) Fu-Jung Lin et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-31 Functions as a Negative Regulator of Lymphatic Vascular Lineage-Specific Differentiation In Vitro and Vascular Development In Vivo

(2010) D. M. Leslie Pedrioli et al.   MOLECULAR AND CELLULAR BIOLOGY

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

(2010) Yingdi Wang et al.   NATURE

prox1b Activity Is Essential in Zebrafish Lymphangiogenesis

(2010) Luca Del Giacco et al.   PLoS One

Zebrafish as a new animal model to study lymphangiogenesis

(2009) Sumio Isogai et al.   ANATOMICAL SCIENCE INTERNATIONAL

Vegfc/Flt4 signalling is suppressed by Dll4 in developing zebrafish intersegmental arteries

(2009) B. M. Hogan et al.   DEVELOPMENT

Sox7 and Sox17 are strain-specific modifiers of the lymphangiogenic defects caused by Sox18 dysfunction in mice

(2009) B. Hosking et al.   DEVELOPMENT

COUP-TFII regulates the functions of Prox1 in lymphatic endothelial cells through direct interaction

(2009) Tomoko Yamazaki et al.   GENES TO CELLS

Vascular defects in a mouse model of hypotrichosis-lymphedema-telangiectasia syndrome indicate a role for SOX18 in blood vessel maturation

(2009) Meredith Downes et al.   HUMAN MOLECULAR GENETICS

FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1

(2009) Camilla Norrmén et al.   JOURNAL OF CELL BIOLOGY

Sumoylation of Prox1 controls its ability to induce VEGFR3 expression and lymphatic phenotypes in endothelial cells

(2009) M.-R. Pan et al.   JOURNAL OF CELL SCIENCE

Identification of targets of Prox1 during in vitro vascular differentiation from embryonic stem cells: functional roles of HoxD8 in lymphangiogenesis

(2009) K. Harada et al.   JOURNAL OF CELL SCIENCE

NFATc1 regulates lymphatic endothelial development

(2009) Rishikesh M. Kulkarni et al.   MECHANISMS OF DEVELOPMENT

ccbe1 is required for embryonic lymphangiogenesis and venous sprouting

(2009) Benjamin M Hogan et al.   NATURE GENETICS

Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth

(2009) Romulo J C Albuquerque et al.   NATURE MEDICINE

Molecular Biology and Pathology of Lymphangiogenesis

(2008) Terhi Karpanen et al.   Annual Review of Pathology-Mechanisms of Disease

Prox1 physically and functionally interacts with COUP-TFII to specify lymphatic endothelial cell fate

(2008) S. Lee et al.   BLOOD

Zebrafish Sox7 and Sox18 function together to control arterial–venous identity

(2008) Hélène Pendeville et al.   DEVELOPMENTAL BIOLOGY

Modulation of transcriptional corepressor activity of prospero-related homeobox protein (Prox1) by SUMO modification

(2008) Shi-fang Shan et al.   FEBS LETTERS

Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity

(2008) N. C. Johnson et al.   GENES & DEVELOPMENT

Diagnosis and Management of Lymphatic Vascular Disease

(2008) Stanley G. Rockson   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Candidate Gene Analysis in Primary Lymphedema

(2008) Robert E. Ferrell et al.   Lymphatic Research and Biology

Sox18 induces development of the lymphatic vasculature in mice

(2008) Mathias François et al.   NATURE

SOX-18 controls endothelial-specific claudin-5 gene expression and barrier function

(2007) Ruud D. Fontijn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Redundant Roles for Sox7 and Sox18 in Arteriovenous Specification in Zebrafish

(2007) Robert Herpers et al.   CIRCULATION RESEARCH

Changes in regulatory molecules for lymphangiogenesis in intestinal lymphangiectasia with enteric protein loss

(2007) Ryota Hokari et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY