Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans

Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

(2010) Li Yang et al.   NATURE MEDICINE

Differential expression of claudin tight junction proteins in the human cortical nephron

(2010) A. Kirk et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis

(2009) Benjamin D. Humphreys et al.   AMERICAN JOURNAL OF PATHOLOGY

Epidermal Notch1 Loss Promotes Skin Tumorigenesis by Impacting the Stromal Microenvironment

(2009) Shadmehr Demehri et al.   CANCER CELL

EMT: When epithelial cells decide to become mesenchymal-like cells

(2009) Raghu Kalluri   JOURNAL OF CLINICAL INVESTIGATION

Uremic memory: the role of acute kidney injury in long-term outcomes

(2009) Ladan Golestaneh et al.   KIDNEY INTERNATIONAL

Deletion of H-Ras decreases renal fibrosis and myofibroblast activation following ureteral obstruction in mice

(2009) M. Teresa Grande et al.   KIDNEY INTERNATIONAL

The Pathogenic Role of Notch Activation in Podocytes

(2009) Thiruvur Niranjan et al.   NEPHRON EXPERIMENTAL NEPHROLOGY

Renal fibrosis is attenuated by targeted disruption of KCa3.1 potassium channels

(2009) I. Grgic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pericytes and Perivascular Fibroblasts Are the Primary Source of Collagen-Producing Cells in Obstructive Fibrosis of the Kidney

(2008) Shuei-Liong Lin et al.   AMERICAN JOURNAL OF PATHOLOGY

Intrinsic Epithelial Cells Repair the Kidney after Injury

(2008) Benjamin D. Humphreys et al.   Cell Stem Cell

Slug is a direct Notch target required for initiation of cardiac cushion cellularization

(2008) Kyle Niessen et al.   JOURNAL OF CELL BIOLOGY

Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo

(2008) Jonas Sjölund et al.   JOURNAL OF CLINICAL INVESTIGATION

Ectopic Notch Activation in Developing Podocytes Causes Glomerulosclerosis

(2008) A. M. Waters et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Notch pathway in podocytes plays a role in the development of glomerular disease

(2008) Thiruvur Niranjan et al.   NATURE MEDICINE

An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice

(2008) Milena Traykova-Brauch et al.   NATURE MEDICINE

Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle development

(2008) F. A. High et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Notch signaling mediates hypoxia-induced tumor cell migration and invasion

(2008) C. Sahlgren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Co-regulation of Gremlin and Notch signalling in diabetic nephropathy

(2007) David W. Walsh et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE