Article
Medicine, General & Internal
David Hoskovec, Zdenek Krska, Jan Skrha, Pavol Klobusicky, Petr Dytrych
Summary: Background and Objectives: Insulinoma is a rare tumor of the Langerhans islets of the pancreas that causes severe hypoglycemia. Surgery is the preferred treatment for insulinomas, and enucleation is the most common type of surgery. Complications, including abscesses and pancreatic fistula, can occur in a significant portion of patients. The centralization of patients is recommended due to the low incidence of the condition.
MEDICINA-LITHUANIA
(2023)
Article
Multidisciplinary Sciences
Evan M. Gordon, Roselyne J. Chauvin, Andrew N. Van, Aishwarya Rajesh, Ashley Nielsen, Dillan J. Newbold, Charles J. Lynch, Nicole A. Seider, Samuel R. Krimmel, Kristen M. Scheidter, Julia Monk, Ryland L. Miller, Athanasia Metoki, David F. Montez, Annie Zheng, Immanuel Elbau, Thomas Madison, Tomoyuki Nishino, Michael J. Myers, Sydney Kaplan, Carolina Badke D'Andrea, Damion V. Demeter, Matthew Feigelis, Julian S. B. Ramirez, Ting Xu, Deanna M. Barch, Christopher D. Smyser, Cynthia E. Rogers, Jan Zimmermann, Kelly N. Botteron, John R. Pruett, Jon T. Willie, Peter Brunner, Joshua S. Shimony, Benjamin P. Kay, Scott Marek, Scott A. Norris, Caterina Gratton, Chad M. Sylvester, Jonathan D. Power, Conor Liston, Deanna J. Greene, Jarod L. Roland, Steven E. Petersen, Marcus E. Raichle, Timothy O. Laumann, Damien A. Fair, Nico U. F. Dosenbach
Summary: Using precision fMRI methods, the study found that the classic homunculus of the motor cortex is interrupted by regions with distinct connectivity and function. These regions, called inter-effector regions, are connected to each other and to the cingulo-opercular network. The inter-effector regions lack movement specificity and co-activate during action planning and axial body movement. The study suggests the existence of a somato-cognitive action network (SCAN) in the motor cortex for whole-body action planning.
Article
Neurosciences
Ahmad Khatoun, Boateng Asamoah, Myles Mc Laughlin
Summary: Recent research suggests that interferential stimulation using ECS electrodes can deliver stronger and more focused electric fields to subcortical regions, compared to IF using TES electrodes.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Medicine, General & Internal
Ronald Lee Korn, Andre Burkett, Jeff Geschwind, Dominic Zygadlo, Taylor Brodie, Derek Cridebring, Daniel D. Von Hoff, Michael J. Demeure
Summary: Despite the availability of various treatments, prognosis for patients with pancreatic adenocarcinoma remains poor. Through radiomics and fat fraction analysis on historical CT scans, specific imaging features of a normal pancreas that could predict the subsequent development of cancer were identified.
Article
Clinical Neurology
Naim Haddad, Yanal Shaheen, Mohammed Abunaib, Gayane Melikyan, Ahmed El Sotouhy, Farah Wahbeh, Areej Nauman, Fatima Al-Maadid, Mohamed Soliman, Boulenouar Mesraoua, Hisham Elkhider, Ziyad Mahfoud
Summary: The study aimed to describe the occurrence and features of Neurocysticercosis (NCC) in Qatar. Clinical practice in Qatar suggests a high occurrence of NCC, even though it is not endemic to the region. Most NCC cases in Qatar are found among immigrants from NCC endemic countries like Nepal and India. Seizures are the most common presenting symptom, with the majority experiencing generalized tonic-clonic seizures. Headaches are also frequently reported. Imaging shows that a significant number of NCC patients have single lesions with calcification, mostly in the frontal lobe. Albendazole is the most commonly used treatment and phenytoin is the most prescribed anti-seizure drug.
FRONTIERS IN NEUROLOGY
(2023)
Article
Clinical Neurology
Barbara Manini, Valeria Vinogradova, Bencie Woll, Donnie Cameron, Martin Eimer, Velia Cardin
Summary: Using functional MRI, researchers found that deaf individuals specifically recruit 'auditory' regions during task switching, and neural activity in the superior temporal regions, especially in the right hemisphere, predicts behavioral performance in deaf individuals. This indicates that sensory cortices can adapt their function to higher-order cognition, suggesting that sensory experience influences cortical reorganization and executive processing in the brain.
Article
Computer Science, Artificial Intelligence
Gianni D'Angelo, Maria Nunzia Scoppettuolo, Anna Lisa Cammarota, Alessandra Rosati, Francesco Palmieri
Summary: Ductal adenocarcinoma of the pancreas is a highly deadly cancer often diagnosed at advanced stages. Machine learning has proven effective in decoding the molecular onset of cancer. This study aims to develop a mathematical model to describe the complex relationship between genetic mutations and disease onset.
Article
Chemistry, Physical
Laura Zorzetto, Ernesto Scoppola, Emeline Raguin, Kerstin G. Blank, Peter Fratzl, Cecile M. Bidan
Summary: Biofilms form when bacteria colonize a surface and produce extracellular matrix components, including mineral particles such as calcium phosphate. Understanding the mineralization mechanisms in biofilms is crucial for disease prevention and the development of biofilm-based living composites.
CHEMISTRY OF MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Robin A. Schoonderwoerd, Pablo de Torres Gutierrez, Ruben Blommers, Anouk W. van Beurden, Tineke C. J. J. Coenen, Nathan J. Klett, Stephan H. Michel, Johanna H. Meijer
Summary: The timing of activity in diurnal and nocturnal mammals is regulated by the central circadian clock of the suprachiasmatic nucleus (SCN). A study found that diurnal rodents have more inhibitory responses to light, which are driven directly by the retinohypothalamic tract (RHT).
Article
Acoustics
Olivier Lartillot, Kristian Nymoen, Guilherme Schmidt Camara, Anne Danielsen
Summary: This article introduces a novel approach to computationally estimate attack regions in audio recordings, aiming to precisely pinpoint the attack position with specific principles. The proposed method shows a significant increase in precision, but at the expense of recall when applied to P-center localization judgments.
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA
(2021)
Article
Materials Science, Multidisciplinary
Jonathan Cappola, Jean-Charles Stinville, Marie-Agathe Charpagne, Patrick G. Callahan, McLean P. Echlin, Tresa M. Pollock, Adam Pilchak, Matthew Kasemer
Summary: The equiaxed microstructure of Ti-6Al-4V alloy contains alpha-phase grains of varying orientations. The presence of microtextured regions can adversely affect the mechanical properties of the alloy, particularly quasi-static and fatigue properties. Studies have shown that orientation spread within microtextured regions facilitates strain localization, and the intensity of microtexture in neighboring regions further influences the extent of strain localization.
Article
Environmental Sciences
Mahmoud Abdel-Gawad, Bedeir Ali-El-Dein, Emad Elsobky, Sanjeev Mehta, Naimet Alsaigh, Thomas Knoll, Mustafa Kura, Guido Kamphuis, Sameh Alhayek, Khaled Alkohlany, Noor Buchholz, Manoj Monga
Summary: In the process of urinary stone formation, a variety of heavy metals and trace elements have been identified. The types and concentrations of these elements vary between different countries. Conventional stone analysis techniques cannot identify stone micro-elements or the concentrations of heavy metals and trace elements, requiring specific tools like ICP-OES. Further research on the microelemental structure of urinary stones could lead to new strategies for prevention and recurrence of stone formation.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Health Care Sciences & Services
Malorie Blancard, Zahia Touat-Hamici, Yuriana Aguilar-Sanchez, Liheng Yin, Guy Vaksmann, Nathalie Roux-Buisson, Veronique Fressart, Isabelle Denjoy, Didier Klug, Nathalie Neyroud, Josefina Ramos-Franco, Ana Maria Gomez, Pascale Guicheney
Summary: A novel RYR2 variant, p.Asp3291Val, was identified in three CPVT families with numerous sudden deaths. This variant results in a loss-of-function RyR2, inducing mild dysfunction in basal conditions but potentially leading to fatal events through its unresponsiveness to adrenergic stimulation.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Article
Geochemistry & Geophysics
Joshua M. R. Muir, Andrew R. Thomson, Feiwu Zhang
Summary: Calcium silicate perovskite and bridgmanite are believed to coexist in the lower mantle and may dissolve into each other to form a single solid solution at certain temperatures. While a widespread MgSiO3-CaSiO3 solid solution is not expected in simplified lower mantle chemistry, the presence of other elements can influence the formation of a mutual solid solution.
EARTH AND PLANETARY SCIENCE LETTERS
(2021)
Article
Surgery
Maitham A. Moslim, Max D. Lefton, Eric A. Ross, Nicholas Mackrides, Sanjay S. Reddy
Summary: Adenosquamous carcinoma (ASC) of the pancreas is a rare and aggressive malignancy that mainly affects women with a median age of 73 years. Most cases present with tumors in the head of the pancreas, show a wide range of clinical manifestations, and are primarily treated with oncological resection.
JOURNAL OF SURGICAL RESEARCH
(2021)
Review
Clinical Neurology
Emma Foster, Benjamin K. -T. Tsang, Anthony Kam, Elsdon Storey, Bruce Day, Aron Hill
JOURNAL OF CLINICAL NEUROSCIENCE
(2015)
Reprint
Neuroimaging
Nisha Pradeep, Robert Nottingham, Anthony Kam, Dheeraj Gandhi, Nasser Razack
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2016)
Article
Clinical Neurology
Chengde Pham, James D. Griffiths, Anthony Kam, Martin K. Hunn
JOURNAL OF CLINICAL NEUROSCIENCE
(2017)
Article
Clinical Neurology
Daniel J. Burkett, Jonathan R. Garst, Jacquelyn P. Hill, Anthony Kam, Douglas E. Anderson
JOURNAL OF NEUROIMAGING
(2017)
Article
Clinical Neurology
Anne L. Abbott, Mauro Silvestrini, Raffi Topakian, Jonathan Golledge, Alejandro M. Brunser, Gert J. de Borst, Robert E. Harbaugh, Fergus N. Doubal, Tatjana Rundek, Ankur Thapar, Alun H. Davies, Anthony Kam, Joanna M. Wardlaw
FRONTIERS IN NEUROLOGY
(2017)
Article
Clinical Neurology
Christopher M. Reid, Elsdon Storey, Tien Y. Wong, Robyn Woods, Andrew Tonkin, Jie Jin Wang, Anthony Kam, Andrew Janke, Rowan Essex, Walter P. Abhayaratna, Marc M. Budge
Editorial Material
Clinical Neurology
Anthony Kam
JOURNAL OF CLINICAL NEUROSCIENCE
(2010)
Article
Clinical Neurology
H. Cheema, D. Federman, A. Kam
JOURNAL OF CLINICAL NEUROSCIENCE
(2011)
Article
Clinical Neurology
Benjamin K. -T. Tsang, Emma Foster, Anthony Kam, Elsdon Storey
JOURNAL OF CLINICAL NEUROSCIENCE
(2013)
Article
Clinical Neurology
Emma Foster, Benjamin K. -T. Tsang, Anthony Kam, Richard J. Stark
JOURNAL OF CLINICAL NEUROSCIENCE
(2014)
Article
Radiology, Nuclear Medicine & Medical Imaging
Richard Chang, McDonald K. Horne, Thomas H. Shawker, Anthony W. Kam, Enn Alexandria Chen, Galen O. Joe, Willie L. Ching, Edie Mao, David A. Wyrick, Jay N. Lozier
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
(2011)
Article
Clinical Neurology
Emma Foster, Benjamin K-T. Tsang, Olga Skibina, Anthony Kam, Elsdon Storey
MULTIPLE SCLEROSIS AND RELATED DISORDERS
(2014)
Editorial Material
Clinical Neurology
Miri Kim, Rachyl Shanker, Anthony Kam, Matthew Reynolds, Joseph C. Serrone
Summary: Coaxial support is a fundamental technique used by neurointerventionalists to optimize distal catheter control within the intracranial circulation. This case study demonstrates the utility of coaxial support in the treatment of a recurrent anterior communicating artery aneurysm. Coaxial support improves catheter control, reduces angulations within the vasculature, limits vessel movement, and provides a lower friction surface for the microcatheter in selected patients.
OPERATIVE NEUROSURGERY
(2021)
Article
Clinical Neurology
Vimal Stanislaus, Anthony Kam, Lily Murphy, Philippe Wolgen, Gill Walker, Pilar Bilbao, Geoffrey C. Cloud
Summary: This study assessed the feasibility and safety of afamelanotide as a potential neuroprotective agent in acute ischemic stroke patients. The results showed that afamelanotide was well tolerated and associated with good treatment response and radiological improvement of salvageable tissue.