Early disruption of glial communication via connexin gap junction in multiple sclerosis, Baló's disease and neuromyelitis optica

Extensive dysregulations of oligodendrocytic and astrocytic connexins are associated with disease progression in an amyotrophic lateral sclerosis mouse model

(2014) Yiwen Cui et al.   Journal of Neuroinflammation

Oligodendrocyte Gap Junction Loss and Disconnection From Reactive Astrocytes in Multiple Sclerosis Gray Matter

(2014) Kyriaki Markoullis et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Gap junctions and hemichannels composed of connexins: potential therapeutic targets for neurodegenerative diseases

(2014) Hideyuki Takeuchi et al.   Frontiers in Cellular Neuroscience

Presence of six different lesion types suggests diverse mechanisms of tissue injury in neuromyelitis optica

(2013) Tatsuro Misu et al.   ACTA NEUROPATHOLOGICA

Astrogliopathy and oligodendrogliopathy are early events in CNS demyelination

(2013) Fanglin Zhang et al.   GLIA

Connexin 43 Astrocytopathy Linked to Rapidly Progressive Multiple Sclerosis and Neuromyelitis Optica

(2013) Katsuhisa Masaki et al.   PLoS One

Clouston Syndrome With HeterozygousGJB6Mutation p.Ala88Val andGJB2Variant p.Val27Ile Revealing Mild Sensorineural Hearing Loss and Photophobia

(2013) Kazumitsu Sugiura et al.   JAMA Dermatology

Extensive loss of connexins in Baló’s disease: evidence for an auto-antibody-independent astrocytopathy via impaired astrocyte–oligodendrocyte/myelin interaction

(2012) Katsuhisa Masaki et al.   ACTA NEUROPATHOLOGICA

Gap junction pathology in multiple sclerosis lesions and normal-appearing white matter

(2012) Kyriaki Markoullis et al.   ACTA NEUROPATHOLOGICA

Neuromyelitis optica lesions may inform multiple sclerosis heterogeneity debate

(2012) Wolfgang Brück et al.   ANNALS OF NEUROLOGY

Disruption of oligodendrocyte gap junctions in experimental autoimmune encephalomyelitis

(2012) Kyriaki Markoullis et al.   GLIA

Deletion of Astroglial Connexins Weakens the Blood–Brain Barrier

(2012) Pascal Ezan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Loss of astrocyte connexins 43 and 30 does not significantly alter susceptibility or severity of acute experimental autoimmune encephalomyelitis in mice

(2012) Sarah E. Lutz et al.   JOURNAL OF NEUROIMMUNOLOGY

ATP and glutamate released via astroglial connexin 43 hemichannels mediate neuronal death through activation of pannexin 1 hemichannels

(2011) Juan A. Orellana et al.   JOURNAL OF NEUROCHEMISTRY

The Gap-junction inhibitor Carbenoxolone suppresses the differentiation of Th17 cells through inhibition of IL-23 expression in antigen presenting cells

(2011) Li Endong et al.   JOURNAL OF NEUROIMMUNOLOGY

The Role of Gap Junctions in Charcot-Marie-Tooth Disease

(2011) K. A. Kleopa   JOURNAL OF NEUROSCIENCE

Autoimmunity in neuromyelitis optica and opticospinal multiple sclerosis: Astrocytopathy as a common denominator in demyelinating disorders

(2011) Jun-ichi Kira   JOURNAL OF THE NEUROLOGICAL SCIENCES

Promoter mutation is a common variant in GJC2-associated Pelizaeus–Merzbacher-like disease

(2011) E. Meyer et al.   MOLECULAR GENETICS AND METABOLISM

Astrocytopathy in Baló’s disease

(2011) Jun-ichi Kira   Multiple Sclerosis Journal

Blockade of Gap Junction Hemichannel Suppresses Disease Progression in Mouse Models of Amyotrophic Lateral Sclerosis and Alzheimer's Disease

(2011) Hideyuki Takeuchi et al.   PLoS One

Aquaporin-4 astrocytopathy in Baló’s disease

(2010) Takeshi Matsuoka et al.   ACTA NEUROPATHOLOGICA

Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination

(2010) Rakhi Sharma et al.   ACTA NEUROPATHOLOGICA

Coexistent Central and Peripheral Nervous System Involvement in a Charcot-Marie-Tooth Syndrome X-linked Patient

(2010) Carlo Fusco et al.   JOURNAL OF CHILD NEUROLOGY

Neuromyelitis optica: a demyelinating disease characterized by acute destruction and regeneration of perivascular astrocytes

(2010) John DE Parratt et al.   Multiple Sclerosis Journal

Deletion of Astrocyte Connexins 43 and 30 Leads to a Dysmyelinating Phenotype and Hippocampal CA1 Vacuolation

(2009) S. E. Lutz et al.   JOURNAL OF NEUROSCIENCE

Blockade of Glutamate Release from Microglia Attenuates Experimental Autoimmune Encephalomyelitis in Mice

(2009) Jin Shijie et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Hereditary spastic paraplegia is a novel phenotype for GJA12/GJC2 mutations

(2008) Jennifer L. Orthmann-Murphy et al.   BRAIN

Gap Junctions Couple Astrocytes and Oligodendrocytes

(2008) Jennifer L. Orthmann-Murphy et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Central Nervous System Signs in X-Linked Charcot-Marie-Tooth Disease After Hyperventilation

(2008) Jayasri Srinivasan et al.   PEDIATRIC NEUROLOGY

Cx29 and Cx32, two connexins expressed by myelinating glia, do not interact and are functionally distinct

(2007) Meejin Ahn et al.   JOURNAL OF NEUROSCIENCE RESEARCH