Wip1 phosphatase is associated with chromatin and dephosphorylates γH2AX to promote checkpoint inhibition

RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

(2009) Carsten Doil et al.   CELL

The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage

(2009) Grant S. Stewart et al.   CELL

Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2

(2009) H Christian Reinhardt et al.   CURRENT OPINION IN CELL BIOLOGY

Wip1 confers G2 checkpoint recovery competence by counteracting p53-dependent transcriptional repression

(2009) Arne Lindqvist et al.   EMBO JOURNAL

The type 2C phosphatase Wip1: An oncogenic regulator of tumor suppressor and DNA damage response pathways

(2008) Xiongbin Lu et al.   CANCER AND METASTASIS REVIEWS

PP4 is a γH2AX phosphatase required for recovery from the DNA damage checkpoint

(2008) Shinichiro Nakada et al.   EMBO REPORTS

PPM1D430, a Novel Alternative Splicing Variant of the Human PPM1D, can Dephosphorylate p53 and Exhibits Specific Tissue Expression

(2008) Y. Chuman et al.   JOURNAL OF BIOCHEMISTRY

Multiple autophosphorylation sites are dispensable for murine ATM activation in vivo

(2008) Jeremy A. Daniel et al.   JOURNAL OF CELL BIOLOGY

ATM Signaling Facilitates Repair of DNA Double-Strand Breaks Associated with Heterochromatin

(2008) Aaron A. Goodarzi et al.   MOLECULAR CELL

Recurrent Initiation: A Mechanism for Triggering p53 Pulses in Response to DNA Damage

(2008) Eric Batchelor et al.   MOLECULAR CELL

FACT-Mediated Exchange of Histone Variant H2AX Regulated by Phosphorylation of H2AX and ADP-Ribosylation of Spt16

(2008) Kyu Heo et al.   MOLECULAR CELL

A PP4-Phosphatase Complex Dephosphorylates γ-H2AX Generated during DNA Replication

(2008) Dipanjan Chowdhury et al.   MOLECULAR CELL

Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery

(2008) Libor Macůrek et al.   NATURE

An Oncogene-Induced DNA Damage Model for Cancer Development

(2008) T. D. Halazonetis et al.   SCIENCE