Exosomal miR-95-5p regulates chondrogenesis and cartilage degradation via histone deacetylase 2/8

Physical exosome:exosome interactions

(2018) Elie Beit-Yannai et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

MicroRNA-92a-3p regulates the expression of cartilage-specific genes by directly targeting histone deacetylase 2 in chondrogenesis and degradation

(2017) G. Mao et al.   OSTEOARTHRITIS AND CARTILAGE

Exosomes: Therapy delivery tools and biomarkers of diseases

(2017) Lucio Barile et al.   PHARMACOLOGY & THERAPEUTICS

Comparison of exosomes secreted by induced pluripotent stem cell-derived mesenchymal stem cells and synovial membrane-derived mesenchymal stem cells for the treatment of osteoarthritis

(2017) Yu Zhu et al.   Stem Cell Research & Therapy

The ASA's Statement onp-Values: Context, Process, and Purpose

(2016) Ronald L. Wasserstein et al.   AMERICAN STATISTICIAN

MicroRNA-455-3p modulates cartilage development and degeneration through modification of histone H3 acetylation

(2016) Weishen Chen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Histone Deacetylases in Cartilage Homeostasis and Osteoarthritis

(2016) Lomeli R. Carpio et al.   Current Rheumatology Reports

Stem Cell-Derived Exosomes: A Potential Alternative Therapeutic Agent in Orthopaedics

(2016) John Burke et al.   Stem Cells International

Osteoarthritis

(2015) S Glyn-Jones et al.   LANCET

Epigenetic Regulation of Chondrocyte Catabolism and Anabolism in Osteoarthritis

(2015) Hyeonkyeong Kim et al.   MOLECULES AND CELLS

Histone Deacetylases in Bone Development and Skeletal Disorders

(2015) Elizabeth W. Bradley et al.   PHYSIOLOGICAL REVIEWS

Exosome and Exosomal MicroRNA: Trafficking, Sorting, and Function

(2015) Jian Zhang et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Histone deacetylase 4 alters cartilage homeostasis in human osteoarthritis

(2015) Jingwei Lu et al.   BMC MUSCULOSKELETAL DISORDERS

Correlation between MMP-13 and HDAC7 expression in human knee osteoarthritis

(2014) Reiji Higashiyama et al.   Modern Rheumatology

Epigenetics of articular cartilage in knee and hip OA

(2014) John Loughlin et al.   Nature Reviews Rheumatology

Class I Histone Deacetylase Inhibition Modulates Metalloproteinase Expression and Blocks Cytokine-Induced Cartilage Degradation

(2013) Kirsty L. Culley et al.   ARTHRITIS AND RHEUMATISM

Epigenetics in osteoarthritis and its implication for future therapeutics

(2013) Gun-Il Im et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Histone deacetylase inhibitors increase microRNA-146a expression and enhance negative regulation of interleukin-1β signaling in osteoarthritis fibroblast-like synoviocytes

(2013) J.H. Wang et al.   OSTEOARTHRITIS AND CARTILAGE

Histone deacetylase inhibitors suppress mechanical stress-induced expression of RUNX-2 and ADAMTS-5 through the inhibition of the MAPK signaling pathway in cultured human chondrocytes

(2012) T. Saito et al.   OSTEOARTHRITIS AND CARTILAGE

Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!)

(2012) F. Berenbaum   OSTEOARTHRITIS AND CARTILAGE

Aging and osteoarthritis

(2011) Richard F. Loeser   CURRENT OPINION IN RHEUMATOLOGY

MiR-365: a mechanosensitive microRNA stimulates chondrocyte differentiation through targeting histone deacetylase 4

(2011) Ying-Jie Guan et al.   FASEB JOURNAL

Alleviation of osteoarthritis by Trichostatin A, a histone deacetylase inhibitor, in experimental osteoarthritis

(2010) Wei-Ping Chen et al.   MOLECULAR BIOLOGY REPORTS

Histone deacetylase 4 promotes TGF-β1-induced synovium-derived stem cell chondrogenesis but inhibits chondrogenically differentiated stem cell hypertrophy

(2009) Ming Pei et al.   DIFFERENTIATION

A novel domain in histone deacetylase 1 and 2 mediates repression of cartilage-specific genes in human chondrocytes

(2009) Sohee Hong et al.   FASEB JOURNAL

Class IIa histone deacetylases: conducting development and differentiation

(2009) Maud Martin et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Biological Functions of miR-29b Contribute to Positive Regulation of Osteoblast Differentiation

(2009) Zhaoyong Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Cartilage-specific Gene Expression in Human Chondrocytes by SirT1 and Nicotinamide Phosphoribosyltransferase

(2008) Mona Dvir-Ginzberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone deacetylase inhibitors suppress interleukin-1β-induced nitric oxide and prostaglandin E2 production in human chondrocytes

(2008) N. Chabane et al.   OSTEOARTHRITIS AND CARTILAGE