Modification of Astrocyte Metabolism as an Approach to the Treatment of Epilepsy: Triheptanoin and Acetyl-l-Carnitine

Complex alterations in microglial M1/M2 markers during the development of epilepsy in two mouse models

(2015) Melissa J. Benson et al.   EPILEPSIA

Triheptanoin improves brain energy metabolism in patients with Huntington disease

(2015) I. M. Adanyeguh et al.   NEUROLOGY

A review of current evidence for acetyl-l-carnitine in the treatment of depression

(2014) Sheng-Min Wang et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Epilepsy surgery in children and adults

(2014) Philippe Ryvlin et al.   LANCET NEUROLOGY

Triheptanoin for Glucose Transporter Type I Deficiency (G1D)

(2014) Juan M. Pascual et al.   JAMA Neurology

Triheptanoin Supplementation to Ketogenic Diet Curbs Cognitive Impairment in APP/PS1 Mice Used as a Model of Familial Alzheimer’s Disease

(2013) Ester Aso et al.   Current Alzheimer Research

Alterations of Hippocampal Glucose Metabolism by Even versus Uneven Medium Chain Triglycerides

(2013) Tanya S McDonald et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Triheptanoin partially restores levels of tricarboxylic acid cycle intermediates in the mouse pilocarpine model of epilepsy

(2013) Mussie G. Hadera et al.   JOURNAL OF NEUROCHEMISTRY

The GLT-1 (EAAT2; slc1a2) glutamate transporter is essential for glutamate homeostasis in the neocortex of the mouse

(2013) Lars Petter Bjørnsen et al.   JOURNAL OF NEUROCHEMISTRY

L-acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors

(2013) C. Nasca et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Carnitine derivatives

(2012) Mariano Malaguarnera   CURRENT OPINION IN GASTROENTEROLOGY

Triheptanoin in acute mouse seizure models

(2012) Nicola K. Thomas et al.   EPILEPSY RESEARCH

Triheptanoin reduces seizure susceptibility in a syndrome-specific mouse model of generalized epilepsy

(2012) Tae Hwan Kim et al.   EPILEPSY RESEARCH

Heptanoate as a Neural Fuel: Energetic and Neurotransmitter Precursors in Normal and Glucose Transporter I-Deficient (G1D) Brain

(2012) Isaac Marin-Valencia et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Dietary supplementation with acetyl-l-carnitine in seizure treatment of pentylenetetrazole kindled mice

(2012) Olav B. Smeland et al.   NEUROCHEMISTRY INTERNATIONAL

Chronic acetyl-l-carnitine alters brain energy metabolism and increases noradrenaline and serotonin content in healthy mice

(2012) Olav B. Smeland et al.   NEUROCHEMISTRY INTERNATIONAL

Standards for epidemiologic studies and surveillance of epilepsy

(2011) David J. Thurman et al.   EPILEPSIA

Triheptanoin—A medium chain triglyceride with odd chain fatty acids: A new anaplerotic anticonvulsant treatment?

(2011) Karin Borges et al.   EPILEPSY RESEARCH

Dietary anaplerotic therapy improves peripheral tissue energy metabolism in patients with Huntington's disease

(2010) Fanny Mochel et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Metabolism of acetyl-l-carnitine for energy and neurotransmitter synthesis in the immature rat brain

(2010) Susanna Scafidi et al.   JOURNAL OF NEUROCHEMISTRY

Anticonvulsant effects of a triheptanoin diet in two mouse chronic seizure models

(2010) Sarah Willis et al.   NEUROBIOLOGY OF DISEASE

High Affinity Carnitine Transporters from OCTN Family in Neural Cells

(2010) Elżbieta Januszewicz et al.   NEUROCHEMICAL RESEARCH

Pyruvate Carboxylation in Different Model Systems Studied by 13C MRS

(2010) Ursula Sonnewald et al.   NEUROCHEMICAL RESEARCH

Is Epilepsy a Preventable Disorder? New Evidence from Animal Models

(2010) Kathryn A. Giblin et al.   NEUROSCIENTIST

Parenteral and enteral metabolism of anaplerotic triheptanoin in normal rats. II. Effects on lipolysis, glucose production, and liver acyl-CoA profile

(2009) Lei Gu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Organic cation/carnitine transporter OCTN3 is present in astrocytes and is up-regulated by peroxisome proliferators-activator receptor agonist

(2009) Elżbieta Januszewicz et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Acylcarnitines: Role in brain

(2009) Lauren L. Jones et al.   PROGRESS IN LIPID RESEARCH

Glucose transporter deficiency syndrome (GLUT1DS) and the ketogenic diet

(2008) Jörg Klepper   EPILEPSIA

Expression of glutamine synthetase and glutamate dehydrogenase in the latent phase and chronic phase in the kainate model of temporal lobe epilepsy

(2008) Janniche Hammer et al.   GLIA

Excitotoxic damage, disrupted energy metabolism, and oxidative stress in the rat brain: antioxidant and neuroprotective effects of l-carnitine

(2008) Daniela Silva-Adaya et al.   JOURNAL OF NEUROCHEMISTRY

The ketogenic diet for the treatment of childhood epilepsy: a randomised controlled trial

(2008) Elizabeth G Neal et al.   LANCET NEUROLOGY

Ketogenic diet is antiepileptogenic in pentylenetetrazole kindled mice and decrease levels of N-acylethanolamines in hippocampus

(2008) Suzanne L. Hansen et al.   NEUROCHEMISTRY INTERNATIONAL

Alternative Medicine and Alzheimer Disease

(2008) Brendan J. Kelley et al.   NEUROLOGIST

Astrocytes in the Epileptic Brain

(2008) Jonathon Wetherington et al.   NEURON

Effects of short-term and long-term treatment with medium- and long-chain triglycerides ketogenic diet on cortical spreading depression in young rats

(2008) Marcela de Almeida Rabello Oliveira et al.   NEUROSCIENCE LETTERS

Functional relevance of carnitine transporter OCTN2 to brain distribution of l-carnitine and acetyl-l-carnitine across the blood-brain barrier

(2003) Yasuto Kido et al.   JOURNAL OF NEUROCHEMISTRY