Pharmacological inhibition of fibroblast growth factor (FGF) receptor signaling ameliorates FGF23-mediated hypophosphatemic rickets

Chronic Inhibition of ERK1/2 Signaling Improves Disordered Bone and Mineral Metabolism in Hypophosphatemic (Hyp) Mice

(2012) Martin Y. H. Zhang et al.   ENDOCRINOLOGY

Intestinal Phosphate Transport

(2011) Yves Sabbagh et al.   ADVANCES IN CHRONIC KIDNEY DISEASE

Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling

(2011) Aline Martin et al.   FASEB JOURNAL

The expanding family of hypophosphatemic syndromes

(2011) Thomas O. Carpenter   JOURNAL OF BONE AND MINERAL METABOLISM

Fibroblast growth factor 23 regulates renal 1,25-dihydroxyvitamin D and phosphate metabolism via the MAP kinase signaling pathway in Hyp mice

(2011) Daniel Ranch et al.   JOURNAL OF BONE AND MINERAL RESEARCH

FGF receptors control vitamin D and phosphate homeostasis by mediating renal FGF-23 signaling and regulating FGF-23 expression in bone

(2011) Simon Wöhrle et al.   JOURNAL OF BONE AND MINERAL RESEARCH

A clinician's guide to X-linked hypophosphatemia

(2011) Thomas O Carpenter et al.   JOURNAL OF BONE AND MINERAL RESEARCH

FGF23 induces left ventricular hypertrophy

(2011) Christian Faul et al.   JOURNAL OF CLINICAL INVESTIGATION

Discovery of 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), A Potent and Selective Inhibitor of the Fibroblast Growth Factor Receptor Family of Receptor Tyrosine Kinase

(2011) Vito Guagnano et al.   JOURNAL OF MEDICINAL CHEMISTRY

Autosomal-Recessive Hypophosphatemic Rickets Is Associated with an Inactivation Mutation in the ENPP1 Gene

(2010) Varda Levy-Litan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Loss-of-Function ENPP1 Mutations Cause Both Generalized Arterial Calcification of Infancy and Autosomal-Recessive Hypophosphatemic Rickets

(2010) Bettina Lorenz-Depiereux et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Compound deletion of Fgfr3 and Fgfr4 partially rescues the Hyp mouse phenotype

(2010) Hua Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The role of pyrophosphate/phosphate homeostasis in terminal differentiation and apoptosis of growth plate chondrocytes

(2010) Hyon Jong Kim et al.   BONE

The Receptor-Dependent Actions of 1,25-Dihydroxyvitamin D Are Required for Normal Growth Plate Maturation in NPt2a Knockout Mice

(2010) Susanne U. Miedlich et al.   ENDOCRINOLOGY

Clinical practice

(2010) Uri S. Alon   EUROPEAN JOURNAL OF PEDIATRICS

Bone histomorphometry: Standardization of nomenclature, symbols, and units: Report of the asbmr histomorphometry nomenclature committee

(2010) A. Michael Parfitt et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Anti-FGF-23 neutralizing antibodies ameliorate muscle weakness and decreased spontaneous movement of Hyp mice

(2010) Yukiko Aono et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Treatment of X-Linked Hypophosphatemia with Calcitriol and Phosphate Increases Circulating Fibroblast Growth Factor 23 Concentrations

(2010) Erik A. Imel et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Inactivation of klotho function induces hyperphosphatemia even in presence of high serum fibroblast growth factor 23 levels in a genetically engineered hypophosphatemic (Hyp) mouse model

(2009) Teruyo Nakatani et al.   FASEB JOURNAL

Therapeutic Effects of Anti-FGF23 Antibodies in Hypophosphatemic Rickets/Osteomalacia*

(2009) Yukiko Aono et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The FGF23–Klotho axis: endocrine regulation of phosphate homeostasis

(2009) M. Shawkat Razzaque   Nature Reviews Endocrinology

Pathogenic role of Fgf23 in Dmp1-null mice

(2008) Shiguang Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Familial tumoral calcinosis and the role of O-glycosylation in the maintenance of phosphate homeostasis

(2008) Ilana Chefetz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

What’s new in hypophosphataemic rickets?

(2008) John M. Pettifor   EUROPEAN JOURNAL OF PEDIATRICS

FGFR3 and FGFR4 Do not Mediate Renal Effects of FGF23

(2008) S. Liu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY