Regulation of the high-affinity copper transporter (hCtr1) expression by cisplatin and heavy metals

The SLC39 family of zinc transporters

(2013) Jeeyon Jeong et al.   MOLECULAR ASPECTS OF MEDICINE

Role of the Human High-Affinity Copper Transporter in Copper Homeostasis Regulation and Cisplatin Sensitivity in Cancer Chemotherapy

(2012) M. T. Kuo et al.   CANCER RESEARCH

An All-Atom Model of the Structure of Human Copper Transporter 1

(2012) Igor F. Tsigelny et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

The oncology drug elesclomol selectively transports copper to the mitochondria to induce oxidative stress in cancer cells

(2012) Masazumi Nagai et al.   FREE RADICAL BIOLOGY AND MEDICINE

Serum depletion of holo-ceruloplasmin induced by silver ions in vivo reduces uptake of cisplatin

(2012) Evgeny A. Zatulovskiy et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Overcoming Platinum Resistance through the Use of a Copper-Lowering Agent

(2012) Siqing Fu et al.   MOLECULAR CANCER THERAPEUTICS

The Relationship of Thioredoxin-1 and Cisplatin Resistance: Its Impact on ROS and Oxidative Metabolism in Lung Cancer Cells

(2012) M. Wangpaichitr et al.   MOLECULAR CANCER THERAPEUTICS

Mechanistic Basis for Overcoming Platinum Resistance Using Copper Chelating Agents

(2012) Z. D. Liang et al.   MOLECULAR CANCER THERAPEUTICS

The Effect of the Extracellular Domain of Human Copper Transporter (hCTR1) on Cisplatin Activation

(2011) Xinghao Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Predictive and prognostic value of human copper transporter 1 (hCtr1) in patients with stage III non-small-cell lung cancer receiving first-line platinum-based doublet chemotherapy

(2011) Helen H.W. Chen et al.   LUNG CANCER

Transcriptional up-regulation of SOD1 by CEBPD: A potential target for cisplatin resistant human urothelial carcinoma cells

(2010) Tzyh-Chyuan Hour et al.   BIOCHEMICAL PHARMACOLOGY

Enhancing Tumor-Specific Uptake of the Anticancer Drug Cisplatin with a Copper Chelator

(2010) Seiko Ishida et al.   CANCER CELL

Ctr1 Is an Apical Copper Transporter in Mammalian Intestinal Epithelial Cellsin VivoThat Is Controlled at the Level of Protein Stability

(2010) Yasuhiro Nose et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Copper Transporters and the Cellular Pharmacology of the Platinum-Containing Cancer Drugs

(2010) S. B. Howell et al.   MOLECULAR PHARMACOLOGY

Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport

(2010) Feng Long et al.   NATURE

Reactivity of platinum-based antitumor drugs towards a Met- and His-rich 20mer peptide corresponding to the N-terminal domain of human copper transporter 1

(2009) Zhengyi Wu et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Effects of zinc supplementation on the survival of patients who received concomitant chemotherapy and radiotherapy for advanced nasopharyngeal carcinoma: Follow-up of a double-blind randomized study with subgroup analysis

(2009) Yung-Song Lin et al.   LARYNGOSCOPE

Coordination of platinum therapeutic agents to met-rich motifs of human copper transport protein1

(2009) Sarah E. Crider et al.   Metallomics

Mechanistic Comparison of Human High-Affinity Copper Transporter 1-Mediated Transport between Copper Ion and Cisplatin

(2009) Z. D. Liang et al.   MOLECULAR PHARMACOLOGY

Three-dimensional structure of the human copper transporter hCTR1

(2009) C. J. De Feo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Platinum compounds 30 years after the introduction of cisplatin: Implications for the treatment of ovarian cancer

(2008) Franco Muggia   GYNECOLOGIC ONCOLOGY

Interaction of cisplatin and analogues with a Met-rich protein site

(2008) Chak Ming Sze et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Elevated GSH Level Increases Cadmium Resistance through Down-Regulation of Sp1-Dependent Expression of the Cadmium Transporter ZIP8

(2008) I. Aiba et al.   MOLECULAR PHARMACOLOGY

Elevated Glutathione Levels Confer Cellular Sensitization to Cisplatin Toxicity by Up-Regulation of Copper Transporter hCtr1

(2008) H. H. W. Chen et al.   MOLECULAR PHARMACOLOGY

Transcription Factor Sp1 Plays an Important Role in the Regulation of Copper Homeostasis in Mammalian Cells

(2008) I.-S. Song et al.   MOLECULAR PHARMACOLOGY