Molecular Basis of Kindlin-2 Binding to Integrin-linked Kinase Pseudokinase for Regulating Cell Adhesion

Integrin function in vascular biology

(2014) Edward F. Plow et al.   CURRENT OPINION IN HEMATOLOGY

Integrin-linked kinase regulates the rate of platelet activation and is essential for the formation of stable thrombi

(2014) C. I. Jones et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Talins and kindlins: partners in integrin-mediated adhesion

(2013) David A. Calderwood et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Integrin-Linked Kinase-PINCH-Parvin Complex Supports Integrin αIIbβ3 Activation

(2013) Shigenori Honda et al.   PLoS One

ILK: a pseudokinase in the center stage of cell-matrix adhesion and signaling

(2012) Jun Qin et al.   CURRENT OPINION IN CELL BIOLOGY

Biophysical Analysis of Kindlin-3 Reveals an Elongated Conformation and Maps Integrin Binding to the Membrane-distal β-Subunit NPXY Motif

(2012) Luke A. Yates et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Molecular Mechanism for the Requirement of PAT-4 (Integrin-linked Kinase (ILK)) for the Localization of UNC-112 (Kindlin) to Integrin Adhesion Sites

(2012) Hiroshi Qadota et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biochemical, Proteomic, Structural, and Thermodynamic Characterizations of Integrin-linked Kinase (ILK)

(2011) Koichi Fukuda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis of Phosphoinositide Binding to Kindlin-2 Protein Pleckstrin Homology Domain in Regulating Integrin Activation

(2011) Jianmin Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane Binding of the N-Terminal Ubiquitin-Like Domain of kindlin-2 Is Crucial for Its Regulation of Integrin Activation

(2011) H. Dhanuja Perera et al.   STRUCTURE

Tyrosine Phosphorylation of Integrin β3Regulates Kindlin-2 Binding and Integrin Activation

(2010) Kamila Bledzka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ancient origin of the integrin-mediated adhesion and signaling machinery

(2010) A. Sebe-Pedros et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrin-linked kinase associated with integrin activation

(2009) S. Honda et al.   BLOOD

How ILK and kindlins cooperate to orchestrate integrin signaling

(2009) Ralph T Böttcher et al.   CURRENT OPINION IN CELL BIOLOGY

Kindling the flame of integrin activation and function with kindlins

(2009) Edward F Plow et al.   CURRENT OPINION IN HEMATOLOGY

The ILK/PINCH/parvin complex: the kinase is dead, long live the pseudokinase!

(2009) Sara A Wickström et al.   EMBO JOURNAL

Kindlin-1 and -2 Directly Bind the C-terminal Region of β Integrin Cytoplasmic Tails and Exert Integrin-specific Activation Effects

(2009) David S. Harburger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrin αvβ3 upregulates integrin-linked kinase expression in human ovarian cancer cells via enhancement of ILK gene transcription

(2009) Daniela Lössner et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The Pseudoactive Site of ILK Is Essential for Its Binding to α-Parvin and Localization to Focal Adhesions

(2009) Koichi Fukuda et al.   MOLECULAR CELL

Integrin-linked kinase is an adaptor with essential functions during mouse development

(2009) Anika Lange et al.   NATURE

The Tail of Integrins, Talin, and Kindlins

(2009) M. Moser et al.   SCIENCE

A dual role for integrin-linked kinase in platelets: regulating integrin function and  -granule secretion

(2008) K. L. Tucker et al.   BLOOD

Kindlins: essential regulators of integrin signalling and cell–matrix adhesion

(2008) Hannu Larjava et al.   EMBO REPORTS

Kindlin-2 controls bidirectional signaling of integrins

(2008) E. Montanez et al.   GENES & DEVELOPMENT

Kindlin-2 (Mig-2): a co-activator of β3integrins

(2008) Yan-Qing Ma et al.   JOURNAL OF CELL BIOLOGY