A Disintegrin and Metalloprotease 17 Dynamic Interaction Sequence, the Sweet Tooth for the Human Interleukin 6 Receptor

Upd3 – An ancestor of the four-helix bundle cytokines

(2013) Mirja Oldefest et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Platelet protein disulfide isomerase is required for thrombus formation but not for hemostasis in mice

(2013) K. Kim et al.   BLOOD

Architecture and Membrane Interactions of the EGF Receptor

(2013) Anton Arkhipov et al.   CELL

Conformational Coupling across the Plasma Membrane in Activation of the EGF Receptor

(2013) Nicholas F. Endres et al.   CELL

Minimal Interleukin 6 (IL-6) Receptor Stalk Composition for IL-6 Receptor Shedding and IL-6 Classic Signaling

(2013) Paul Baran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane-Proximal Domain of a Disintegrin and Metalloprotease-17 Represents the Putative Molecular Switch of Its Shedding Activity Operated by Protein-disulfide Isomerase

(2013) Stefan Düsterhöft et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Protein Disulfide Isomerase/Thioredoxin-1 Complex Is Physically Attached to Exofacial Membrane Tumor Necrosis Factor Receptors: Overexpression in Chronic Lymphocytic Leukemia Cells

(2012) Anita Söderberg et al.   ANTIOXIDANTS & REDOX SIGNALING

Protein disulfide isomerase capture during thrombus formation in vivo depends on the presence of  3 integrins

(2012) J. Cho et al.   BLOOD

The membrane-proximal domain of A Disintegrin and Metalloprotease 17 (ADAM17) is responsible for recognition of the interleukin-6 receptor and interleukin-1 receptor II

(2012) Inken Lorenzen et al.   FEBS LETTERS

A Role for cGMP in Inducible Nitric-oxide Synthase (iNOS)-induced Tumor Necrosis Factor (TNF) α-converting Enzyme (TACE/ADAM17) Activation, Translocation, and TNF Receptor 1 (TNFR1) Shedding in Hepatocytes

(2012) R. Savanh Chanthaphavong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

A Disintegrin and Metalloenzyme (ADAM) 17 Activation Is Regulated by α5β1 Integrin in Kidney Mesangial Cells

(2012) Pal Gooz et al.   PLoS One

Anti-Tumour Effects of a Specific Anti-ADAM17 Antibody in an Ovarian Cancer Model In Vivo

(2012) Frances M. Richards et al.   PLoS One

Multimerisation of A disintegrin and metalloprotease protein-17 (ADAM17) is mediated by its EGF-like domain

(2011) Inken Lorenzen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The pro- and anti-inflammatory properties of the cytokine interleukin-6

(2011) Jürgen Scheller et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Treatment of TNF mediated diseases by selective inhibition of soluble TNF or TNFR1

(2011) Filip Van Hauwermeiren et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Species Specificity of ADAM10 and ADAM17 Proteins in Interleukin-6 (IL-6) Trans-signaling and Novel Role of ADAM10 in Inducible IL-6 Receptor Shedding

(2011) Christoph Garbers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling

(2011) Simon A. Jones et al.   JOURNAL OF CLINICAL INVESTIGATION

Leukocyte ADAM17 Regulates Acute Pulmonary Inflammation

(2011) Patrick G. Arndt et al.   PLoS One

Cross-domain inhibition of TACE ectodomain

(2011) C. J. Tape et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Galectin-9 binding to cell surface protein disulfide isomerase regulates the redox environment to enhance T-cell migration and HIV entry

(2011) S. Bi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ADAM17: a molecular switch to control inflammation and tissue regeneration

(2011) Jürgen Scheller et al.   TRENDS IN IMMUNOLOGY

Thiol isomerases negatively regulate the cellular shedding activity of ADAM17

(2010) Sofie H. Willems et al.   BIOCHEMICAL JOURNAL

Helicobacter pylori CagL Activates ADAM17 to Induce Repression of the Gastric H, K-ATPase α Subunit

(2010) Arindam Saha et al.   GASTROENTEROLOGY

ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site

(2010) S. M. Le Gall et al.   JOURNAL OF CELL SCIENCE

Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice

(2010) Athena Chalaris et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of Mature ADAM17 by Redox Agents for L-Selectin Shedding

(2009) Y. Wang et al.   JOURNAL OF IMMUNOLOGY

ADAMs 10 and 17 Represent Differentially Regulated Components of a General Shedding Machinery for Membrane Proteins Such as Transforming Growth Factor α, L-Selectin, and Tumor Necrosis Factor α

(2009) Sylvain M. Le Gall et al.   MOLECULAR BIOLOGY OF THE CELL

HELIQUEST: a web server to screen sequences with specific  -helical properties

(2008) R. Gautier et al.   BIOINFORMATICS

Interaction and functional association of protein disulfide isomerase with αVβ3 integrin on endothelial cells

(2008) Maria Swiatkowska et al.   FEBS Journal

Three-dimensional domain architecture of the ADAM family proteinases

(2008) Soichi Takeda   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The good, the bad and the ugly substrates for ADAM10 and ADAM17 in brain pathology, inflammation and cancer

(2008) Jessica Pruessmeyer et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY