Regulated Intramembrane Proteolysis of the Frontotemporal Lobar Degeneration Risk Factor, TMEM106B, by Signal Peptide Peptidase-like 2a (SPPL2a)
出版年份 2014 全文链接
标题
Regulated Intramembrane Proteolysis of the Frontotemporal Lobar Degeneration Risk Factor, TMEM106B, by Signal Peptide Peptidase-like 2a (SPPL2a)
作者
关键词
-
出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 289, Issue 28, Pages 19670-19680
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2014-05-29
DOI
10.1074/jbc.m113.515700
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions
- (2014) Michael D. Gallagher et al. ACTA NEUROPATHOLOGICA
- TMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia
- (2014) Marka van Blitterswijk et al. ACTA NEUROPATHOLOGICA
- The Intramembrane Proteases Signal Peptide Peptidase-Like 2a and 2b Have Distinct Functions In Vivo
- (2014) J. Schneppenheim et al. MOLECULAR AND CELLULAR BIOLOGY
- The FTLD risk factor TMEM106B and MAP6 control dendritic trafficking of lysosomes
- (2013) Benjamin M. Schwenk et al. EMBO JOURNAL
- The transferrin receptor-1 membrane stub undergoes intramembrane proteolysis by signal peptide peptidase-like 2b
- (2013) Claudia Zahn et al. FEBS Journal
- TMEM106B and APOE polymorphisms interact to confer risk for late-onset Alzheimer’s disease in Han Chinese
- (2013) Rui-Chun Lu et al. JOURNAL OF NEURAL TRANSMISSION
- TMEM106B p.T185S regulates TMEM106B protein levels: implications for frontotemporal dementia
- (2013) Alexandra M. Nicholson et al. JOURNAL OF NEUROCHEMISTRY
- The frontotemporal lobar degeneration risk factor, TMEM106B, regulates lysosomal morphology and function
- (2012) Owen A. Brady et al. HUMAN MOLECULAR GENETICS
- Membrane Orientation and Subcellular Localization of Transmembrane Protein 106B (TMEM106B), a Major Risk Factor for Frontotemporal Lobar Degeneration
- (2012) Christina M. Lang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8−dendritic cells require the intramembrane endopeptidase SPPL2A
- (2012) Hannes Bergmann et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain
- (2012) Janna Schneppenheim et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain
- (2012) Daniel R. Beisner et al. JOURNAL OF EXPERIMENTAL MEDICINE
- TMEM106B, the Risk Gene for Frontotemporal Dementia, Is Regulated by the microRNA-132/212 Cluster and Affects Progranulin Pathways
- (2012) A. S. Chen-Plotkin et al. JOURNAL OF NEUROSCIENCE
- TMEM106B risk variant is implicated in the pathologic presentation of Alzheimer disease
- (2012) N. J. Rutherford et al. NEUROLOGY
- TMEM106B is associated with frontotemporal lobar degeneration in a clinically diagnosed patient cohort
- (2011) Julie van der Zee et al. BRAIN
- Signal-peptide-peptidase-like 2a (SPPL2a) is targeted to lysosomes/late endosomes by a tyrosine motif in its C-terminal tail
- (2011) Jörg Behnke et al. FEBS LETTERS
- The α-Helical Content of the Transmembrane Domain of the British Dementia Protein-2 (Bri2) Determines Its Processing by Signal Peptide Peptidase-like 2b (SPPL2b)
- (2011) Regina Fluhrer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulated intramembrane proteolysis - lessons from amyloid precursor protein processing
- (2011) Stefan F. Lichtenthaler et al. JOURNAL OF NEUROCHEMISTRY
- Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega
- (2011) F. Sievers et al. Molecular Systems Biology
- Database resources of the National Center for Biotechnology Information
- (2011) E. W. Sayers et al. NUCLEIC ACIDS RESEARCH
- Intramembrane Proteolysis in Regulated Protein Trafficking
- (2011) Marius K. Lemberg TRAFFIC
- Risk genotypes at TMEM106B are associated with cognitive impairment in amyotrophic lateral sclerosis
- (2010) Ryan Vass et al. ACTA NEUROPATHOLOGICA
- Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions
- (2010) Vivianna M Van Deerlin et al. NATURE GENETICS
- Intramembrane Proteolysis by Signal Peptide Peptidases: A Comparative Discussion of GXGD-type Aspartyl Proteases
- (2009) Regina Fluhrer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SitePredicting the cleavage of proteinase substrates
- (2009) Jelle Verspurten et al. TRENDS IN BIOCHEMICAL SCIENCES
- Intramembrane Proteolysis by γ-Secretase
- (2008) Harald Steiner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Substrate Requirements for SPPL2b-dependent Regulated Intramembrane Proteolysis
- (2008) Lucas Martin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The ADAM metalloproteinases
- (2008) D EDWARDS et al. MOLECULAR ASPECTS OF MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now