Bisretinoid-mediated Complement Activation on Retinal Pigment Epithelial Cells Is Dependent on Complement Factor H Haplotype

The use of cultured human fetal retinal pigment epithelium in studies of the classical retinoid visual cycle and retinoid-based disease processes

(2013) Jane Hu et al.   EXPERIMENTAL EYE RESEARCH

Oxidative Stress Sensitizes Retinal Pigmented Epithelial (RPE) Cells to Complement-mediated Injury in a Natural Antibody-, Lectin Pathway-, and Phospholipid Epitope-dependent Manner

(2013) Kusumam Joseph et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toward a structure-based comprehension of the lectin pathway of complement

(2013) Troels R. Kjaer et al.   MOLECULAR IMMUNOLOGY

ABCA4 is an N-retinylidene-phosphatidylethanolamine and phosphatidylethanolamine importer

(2012) Faraz Quazi et al.   Nature Communications

Sub-lytic C5b-9 induces functional changes in retinal pigment epithelial cells consistent with age-related macular degeneration

(2011) K Lueck et al.   EYE

Complement in age-related macular degeneration: a focus on function

(2011) D T Bradley et al.   EYE

The role of ficolins in the lectin pathway of innate immunity

(2011) Yuichi Endo et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Complement System Dysregulation and Inflammation in the Retinal Pigment Epithelium of a Mouse Model for Stargardt Macular Degeneration

(2011) Roxana A. Radu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complement factor H binds malondialdehyde epitopes and protects from oxidative stress

(2011) David Weismann et al.   NATURE

A rare penetrant mutation in CFH confers high risk of age-related macular degeneration

(2011) Soumya Raychaudhuri et al.   NATURE GENETICS

Cell culture model that mimics drusen formation and triggers complement activation associated with age-related macular degeneration

(2011) L. V. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD)

(2010) Lars G. Fritsche et al.   HUMAN MOLECULAR GENETICS

Forecasting Age-Related Macular Degeneration Through the Year 2050

(2009) David B. Rein   ARCHIVES OF OPHTHALMOLOGY

Novel Lipofuscin Bisretinoids Prominent in Human Retina and in a Model of Recessive Stargardt Disease

(2009) Yalin Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The pivotal role of the complement system in aging and age-related macular degeneration: Hypothesis re-visited

(2009) Don H. Anderson et al.   PROGRESS IN RETINAL AND EYE RESEARCH