Proprotein Convertase Subtilisin/Kexin Type 7 (PCSK7) Is Essential for the Zebrafish Development and Bioavailability of Transforming Growth Factor β1a (TGFβ1a)

Implication of the proprotein convertases in iron homeostasis: Proprotein convertase 7 sheds human transferrin receptor 1 and furin activates hepcidin

(2013) Johann Guillemot et al.   HEPATOLOGY

Internalization of Proprotein Convertase PC7 from Plasma Membrane Is Mediated by a Novel Motif

(2012) Jeroen Declercq et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of Endothelial Furin Leads to Cardiac Malformation and Early Postnatal Death

(2012) W. Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

Automated design of ligands to polypharmacological profiles

(2012) Jérémy Besnard et al.   NATURE

The biology and therapeutic targeting of the proprotein convertases

(2012) Nabil G. Seidah et al.   NATURE REVIEWS DRUG DISCOVERY

A Homolog of Subtilisin-Like Proprotein Convertase 7 Is Essential to Anterior Neural Development in Xenopus

(2012) Sema Senturker et al.   PLoS One

Identification of proprotein convertase substrates using genome-wide expression correlation analysis

(2011) Hannu Turpeinen et al.   BMC GENOMICS

Lessons from morpholino-based screening in zebrafish

(2011) V. M. Bedell et al.   Briefings in Functional Genomics

The microenvironment patterns the pluripotent mouse epiblast through paracrine Furin and Pace4 proteolytic activities

(2011) D. Mesnard et al.   GENES & DEVELOPMENT

Proprotein Convertase PC7 Enhances the Activation of the EGF Receptor Pathway through Processing of the EGF Precursor

(2011) Estelle Rousselet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels

(2010) Konrad Oexle et al.   HUMAN MOLECULAR GENETICS

Post-Endoplasmic Reticulum Rescue of Unstable MHC Class I Requires Proprotein Convertase PC7

(2010) R. M. Leonhardt et al.   JOURNAL OF IMMUNOLOGY

PCSK2-null mice exhibit delayed intestinal motility, reduced refeeding response and altered plasma levels of several regulatory peptides

(2010) Jeffrey Gagnon et al.   LIFE SCIENCES

PCSK9-deficient mice exhibit impaired glucose tolerance and pancreatic islet abnormalities

(2009) Majambu Mbikay et al.   FEBS LETTERS

Site-specific Cleavage of BMP4 by Furin, PC6, and PC7

(2009) Sylvia M. Nelsen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Controlling morpholino experiments: don't stop making antisense

(2008) J. S. Eisen et al.   DEVELOPMENT

Substrate Cleavage Analysis of Furin and Related Proprotein Convertases

(2008) Albert G. Remacle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance

(2008) Marko Pesu et al.   NATURE

High-resolution in situ hybridization to whole-mount zebrafish embryos

(2007) Christine Thisse et al.   Nature Protocols