Mutational Analysis Identifies Residues Crucial for Homodimerization of Myeloid Differentiation Factor 88 (MyD88) and for Its Function in Immune Cells

Molecular Basis of NF-κB Signaling

(2013) Johanna Napetschnig et al.   Annual Review of Biophysics

Targeting the Toll-like Receptor/Interleukin 1 Receptor Pathway in Human Diseases: Rational Design of MyD88 Inhibitors

(2013) Maria Loiarro et al.   Clinical Lymphoma Myeloma & Leukemia

Suppression of TLR Signaling by Targeting TIR domain-Containing Proteins

(2013) Ota Fekonja et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Pathogen Recognition Receptors: Ligands and Signaling Pathways by Toll-Like Receptors

(2013) Miwa Sasai et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Identification of Binding Sites for Myeloid Differentiation Primary Response Gene 88 (MyD88) and Toll-like Receptor 4 in MyD88 Adapter-like (Mal)

(2013) Celia Bovijn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anti-Inflammatory Therapy in Chronic Disease: Challenges and Opportunities

(2013) I. Tabas et al.   SCIENCE

Roles of toll-like receptors in Cancer: A double-edged sword for defense and offense

(2012) Shaherin Basith et al.   ARCHIVES OF PHARMACAL RESEARCH

Molecular analysis of the binding mode of Toll/interleukin-1 receptor (TIR) domain proteins during TLR2 signaling

(2012) Masatoshi Nada et al.   MOLECULAR IMMUNOLOGY

MYD88 L265P Somatic Mutation in Waldenström's Macroglobulinemia

(2012) Steven P. Treon et al.   NEW ENGLAND JOURNAL OF MEDICINE

TRAM Is Involved in IL-18 Signaling and Functions as a Sorting Adaptor for MyD88

(2012) Hidenori Ohnishi et al.   PLoS One

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Identification of Interaction Sites for Dimerization and Adapter Recruitment in Toll/Interleukin-1 Receptor (TIR) Domain of Toll-like Receptor 4

(2011) Celia Bovijn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection

(2011) E. Valkov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TLR-signaling Networks

(2010) J. Brown et al.   JOURNAL OF DENTAL RESEARCH

Targeting TLR/IL-1R Signalling in Human Diseases

(2010) Maria Loiarro et al.   MEDIATORS OF INFLAMMATION

Oncogenically active MYD88 mutations in human lymphoma

(2010) Vu N. Ngo et al.   NATURE

Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling

(2010) Su-Chang Lin et al.   NATURE

Pharmacological inhibition of TLR9 activation blocks autoantibody production in human B cells from SLE patients

(2010) Federica Capolunghi et al.   RHEUMATOLOGY

The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress

(2009) Luke A. J. O'Neill   IMMUNOLOGICAL REVIEWS

Identification of Critical Residues of the MyD88 Death Domain Involved in the Recruitment of Downstream Kinases

(2009) Maria Loiarro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling

(2009) H. Ohnishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Crystal Structure of the Human Toll-like Receptor 10 Cytoplasmic Domain Reveals a Putative Signaling Dimer

(2008) Tomas Nyman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FireDock: a web server for fast interaction refinement in molecular docking

(2008) E. Mashiach et al.   NUCLEIC ACIDS RESEARCH

Pyogenic Bacterial Infections in Humans with MyD88 Deficiency

(2008) H. von Bernuth et al.   SCIENCE