TheMycobacterium tuberculosisSecreted Protein Rv0203 Transfers Heme to Membrane Proteins MmpL3 and MmpL11

A New Way to Degrade Heme

(2013) Shusuke Nambu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery of a Siderophore Export System Essential for Virulence of Mycobacterium tuberculosis

(2013) Ryan M. Wells et al.   PLoS Pathogens

SQ109 Targets MmpL3, a Membrane Transporter of Trehalose Monomycolate Involved in Mycolic Acid Donation to the Cell Wall Core of Mycobacterium tuberculosis

(2012) Kapil Tahlan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Characterization of Heme Ligation Properties of Rv0203, a Secreted Heme Binding Protein Involved in Mycobacterium tuberculosis Heme Uptake

(2012) Cedric P. Owens et al.   BIOCHEMISTRY

Screening a library of 1600 adamantyl ureas for anti-Mycobacterium tuberculosis activity in vitro and for better physical chemical properties for bioavailability

(2012) Michael S. Scherman et al.   BIOORGANIC & MEDICINAL CHEMISTRY

MmpL Genes Are Associated with Mycolic Acid Metabolism in Mycobacteria and Corynebacteria

(2012) Cristian Varela et al.   CHEMISTRY & BIOLOGY

Mapping Ultra-weak Protein-Protein Interactions between Heme Transporters ofStaphylococcus aureus

(2012) Ryota Abe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane

(2012) Anna E Grzegorzewicz et al.   Nature Chemical Biology

Structure and mechanism of the tripartite CusCBA heavy-metal efflux complex

(2012) F. Long et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Differential Function of Lip Residues in the Mechanism and Biology of an Anthrax Hemophore

(2012) MarCia T. Ekworomadu et al.   PLoS Pathogens

Heme Uptake by Leishmania amazonensis Is Mediated by the Transmembrane Protein LHR1

(2012) Chau Huynh et al.   PLoS Pathogens

MmpL3 Is the Cellular Target of the Antitubercular Pyrrole Derivative BM212

(2011) Valentina La Rosa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The H93G myoglobin cavity mutant as a versatile scaffold for modeling heme iron coordination structures in protein active sites and their characterization with magnetic circular dichroism spectroscopy

(2011) Jing Du et al.   COORDINATION CHEMISTRY REVIEWS

Heme binding to the second, lower-affinity site of the global iron regulator Irr from Rhizobium leguminosarum promotes oligomerization

(2011) Gaye F. White et al.   FEBS Journal

Mycobacterium tuberculosis Can Utilize Heme as an Iron Source

(2011) C. M. Jones et al.   JOURNAL OF BACTERIOLOGY

Switch or Funnel: How RND-Type Transport Systems Control Periplasmic Metal Homeostasis

(2011) E.-H. Kim et al.   JOURNAL OF BACTERIOLOGY

Elucidation and Chemical Modulation of Sulfolipid-1 Biosynthesis inMycobacterium tuberculosis

(2011) Jessica C. Seeliger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transient Weak Protein–Protein Complexes Transfer Heme Across the Cell Wall of Staphylococcus aureus

(2011) Valerie A. Villareal et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Crystal structure of the CusBA heavy-metal efflux complex of Escherichia coli

(2011) Chih-Chia Su et al.   NATURE

Structure and function of a membrane component SecDF that enhances protein export

(2011) Tomoya Tsukazaki et al.   NATURE

Discovery and characterization of a unique mycobacterial heme acquisition system

(2011) M. V. Tullius et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prediction of protein secondary structure from circular dichroism using theoretically derived spectra

(2011) Caroline Louis-Jeune et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Molecular basis for the inability of an oxygen atom donor ligand to replace the natural sulfur donor heme axial ligand in cytochrome P450 catalysis. Spectroscopic characterization of the Cys436Ser CYP2B4 mutant

(2010) Roshan Perera et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

ABCG2 Transports and Transfers Heme to Albumin through Its Large Extracellular Loop

(2010) Elodie Desuzinges-Mandon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Heme-responsive DNA Binding by the Global Iron Regulator Irr fromRhizobium leguminosarum

(2010) Chloe Singleton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Specificity of Staphyloferrin B Recognition by the SirA Receptor fromStaphylococcus aureus

(2010) Jason C. Grigg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two Stacked Heme Molecules in the Binding Pocket of the Periplasmic Heme-Binding Protein HmuT from Yersinia pestis

(2010) Daniel Mattle et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure, function and inhibition of RND efflux pumps in Gram-negative bacteria: an update

(2009) Jessica MA Blair et al.   CURRENT OPINION IN MICROBIOLOGY

Heme Transfer to the Bacterial Cell Envelope Occurs via a Secreted Hemophore in the Gram-positive PathogenBacillus anthracis

(2009) Marian Fabian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural biology of heme binding in the Staphylococcus aureus Isd system

(2009) Jason C. Grigg et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Crystal Structure of the Multidrug Exporter MexB from Pseudomonas aeruginosa

(2009) Gaby Sennhauser et al.   JOURNAL OF MOLECULAR BIOLOGY

Heme Uptake by Microscilla marina and Evidence for Heme Uptake Systems in the Genomes of Diverse Marine Bacteria

(2008) B. M. Hopkinson et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Bacterial heme-transport proteins and their heme-coordination modes

(2008) Yong Tong et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Pathway for Heme Uptake from Human Methemoglobin by the Iron-regulated Surface Determinants System ofStaphylococcus aureus

(2008) Hui Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Demonstration of the Iron-regulated Surface Determinant (Isd) Heme Transfer Pathway inStaphylococcus aureus

(2008) Naomi Muryoi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct Hemin Transfer from IsdA to IsdC in the Iron-regulated Surface Determinant (Isd) Heme Acquisition System ofStaphylococcus aureus

(2008) Mengyao Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Jpred 3 secondary structure prediction server

(2008) C. Cole et al.   NUCLEIC ACIDS RESEARCH

Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5–MmpL5 efflux system

(2008) Anna Milano et al.   TUBERCULOSIS