Conformational variation in structures of classical and non-classical MHCII proteins and functional implications

A Peptide/MHCII conformer generated in the presence of exchange peptide is substrate for HLA-DM editing

(2012) Andrea Ferrante et al.   Scientific Reports

An Insertion Mutant in DQA1*0501 Restores Susceptibility to HLA-DM: Implications for Disease Associations

(2011) T. Hou et al.   JOURNAL OF IMMUNOLOGY

Conformational lability in the class II MHC 310 helix and adjacent extended strand dictate HLA-DM susceptibility and peptide exchange

(2011) C. A. Painter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted regulation of self-peptide presentation prevents type I diabetes in mice without disrupting general immunocompetence

(2010) Woelsung Yi et al.   JOURNAL OF CLINICAL INVESTIGATION

310helices in channels and other membrane proteins

(2010) Ricardo Simão Vieira-Pires et al.   JOURNAL OF GENERAL PHYSIOLOGY

HLA-DM captures partially empty HLA-DR molecules for catalyzed removal of peptide

(2010) Anne-Kathrin Anders et al.   NATURE IMMUNOLOGY

Bidirectional binding of invariant chain peptides to an MHC class II molecule

(2010) S. Gunther et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nomenclature for factors of the HLA system, 2010

(2010) S. G. E. Marsh et al.   TISSUE ANTIGENS

Cutting Edge: HLA-DM Functions through a Mechanism That Does Not Require Specific Conserved Hydrogen Bonds in Class II MHC-Peptide Complexes

(2009) Z. Zhou et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: HLA-DM-Mediated Peptide Exchange Functions Normally on MHC Class II-Peptide Complexes That Have Been Weakened by Elimination of a Conserved Hydrogen Bond

(2009) A. Ferrante et al.   JOURNAL OF IMMUNOLOGY

Flexibility of the MHC class II peptide binding cleft in the bound, partially filled, and empty states: A molecular dynamics simulation study

(2008) Rakina Yaneva et al.   BIOPOLYMERS

The IMGT/HLA database

(2008) J. Robinson et al.   NUCLEIC ACIDS RESEARCH

Anchor Side Chains of Short Peptide Fragments Trigger Ligand-Exchange of Class II MHC Molecules

(2008) Shashank Gupta et al.   PLoS One

Model for the Peptide-Free Conformation of Class II MHC Proteins

(2008) Corrie A. Painter et al.   PLoS One

HLA-DM Mediates Epitope Selection by a “Compare-Exchange” Mechanism when a Potential Peptide Pool Is Available

(2008) Andrea Ferrante et al.   PLoS One

A Systematic Assessment of MHC Class II Peptide Binding Predictions and Evaluation of a Consensus Approach

(2008) Peng Wang et al.   PLoS Computational Biology