Characterization of a Highly Efficient Blue-shifted Channelrhodopsin from the Marine AlgaPlatymonas subcordiformis

Improved Orange and Red Ca2+ Indicators and Photophysical Considerations for Optogenetic Applications

(2013) Jiahui Wu et al.   ACS Chemical Neuroscience

Intramolecular Proton Transfer in Channelrhodopsins

(2013) Oleg A. Sineshchekov et al.   BIOPHYSICAL JOURNAL

Optogenetic manipulation of neural and non-neural functions

(2013) Hiromu Yawo et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

From channelrhodopsins to optogenetics

(2013) Peter Hegemann et al.   EMBO Molecular Medicine

Degradation of channelopsin-2 in the absence of retinal and degradation resistance in certain mutants

(2012) Sybille Ullrich et al.   BIOLOGICAL CHEMISTRY

Molecular Tools and Approaches for Optogenetics

(2012) Yuan Mei et al.   BIOLOGICAL PSYCHIATRY

Color-tuned Channelrhodopsins for Multiwavelength Optogenetics

(2012) Matthias Prigge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HAMP Domain Signal Relay Mechanism in a Sensory Rhodopsin-Transducer Complex

(2012) Jihong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium Rubies: A Family of Red-Emitting Functionalizable Indicators Suitable for Two-Photon Ca2+ Imaging

(2012) Mayeul Collot et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Crystal structure of the channelrhodopsin light-gated cation channel

(2012) Hideaki E. Kato et al.   NATURE

pHTomato, a red, genetically encoded indicator that enables multiplex interrogation of synaptic activity

(2012) Yulong Li et al.   NATURE NEUROSCIENCE

Probing the function of neuronal populations: Combining micromirror-based optogenetic photostimulation with voltage-sensitive dye imaging

(2012) Sachiko Tsuda et al.   NEUROSCIENCE RESEARCH

Re-Introduction of Transmembrane Serine Residues Reduce the Minimum Pore Diameter of Channelrhodopsin-2

(2012) Ryan Richards et al.   PLoS One

Glutamate residue 90 in the predicted transmembrane domain 2 is crucial for cation flux through channelrhodopsin 2

(2011) Karelia Ruffert et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Rectification of the Channelrhodopsin Early Conductance

(2011) Dietrich Gradmann et al.   BIOPHYSICAL JOURNAL

The Microbial Opsin Family of Optogenetic Tools

(2011) Feng Zhang et al.   CELL

Bioinformatic and Mutational Analysis of Channelrhodopsin-2 Protein Cation-conducting Pathway

(2011) Anna Pia Plazzo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neocortical excitation/inhibition balance in information processing and social dysfunction

(2011) Ofer Yizhar et al.   NATURE

A gene-fusion strategy for stoichiometric and co-localized expression of light-gated membrane proteins

(2011) Sonja Kleinlogel et al.   NATURE METHODS

Principles for applying optogenetic tools derived from direct comparative analysis of microbial opsins

(2011) Joanna Mattis et al.   NATURE METHODS

Diversity of Chlamydomonas Channelrhodopsins

(2011) Sing-Yi Hou et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

High-efficiency channelrhodopsins for fast neuronal stimulation at low light levels

(2011) A. Berndt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New Channelrhodopsin with a Red-Shifted Spectrum and Rapid Kinetics from Mesostigma viride

(2011) E. G. Govorunova et al.   mBio

Two Open States with Progressive Proton Selectivities in the Branched Channelrhodopsin-2 Photocycle

(2010) André Berndt et al.   BIOPHYSICAL JOURNAL

The Photocycle of Channelrhodopsin-2: Ultrafast Reaction Dynamics and Subsequent Reaction Steps

(2010) Mirka-Kristin Verhoefen et al.   CHEMPHYSCHEM

Optogenetics

(2010) Karl Deisseroth   NATURE METHODS

Channelrhodopsin engineering and exploration of new optogenetic tools

(2010) Peter Hegemann et al.   NATURE METHODS

Ultrafast optogenetic control

(2010) Lisa A Gunaydin et al.   NATURE NEUROSCIENCE

Characterization of Engineered Channelrhodopsin Variants with Improved Properties and Kinetics

(2009) John Y. Lin et al.   BIOPHYSICAL JOURNAL

The retinal structure of channelrhodopsin-2 assessed by resonance Raman spectroscopy

(2009) Melanie Nack et al.   FEBS LETTERS

Faithful Expression of Multiple Proteins via 2A-Peptide Self-Processing: A Versatile and Reliable Method for Manipulating Brain Circuits

(2009) W. Tang et al.   JOURNAL OF NEUROSCIENCE

Glu 87 of Channelrhodopsin-1 Causes pH-dependent Color Tuning and Fast Photocurrent Inactivation

(2009) Satoshi P. Tsunoda et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Channelrhodopsins of Volvox carteri Are Photochromic Proteins That Are Specifically Expressed in Somatic Cells under Control of Light, Temperature, and the Sex Inducer

(2009) A. Kianianmomeni et al.   PLANT PHYSIOLOGY

Channelrhodopsin-2 is a leaky proton pump

(2009) K. Feldbauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Informational Lesions: Optical Perturbation of Spike Timing and Neural Synchrony Via Microbial Opsin Gene Fusions

(2009) Xue Han   Frontiers in Molecular Neuroscience

Algal Sensory Photoreceptors

(2008) Peter Hegemann   Annual Review of Plant Biology

Molecular Determinants Differentiating Photocurrent Properties of Two Channelrhodopsins fromChlamydomonas

(2008) Hongxia Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Monitoring Light-induced Structural Changes of Channelrhodopsin-2 by UV-visible and Fourier Transform Infrared Spectroscopy

(2008) Eglof Ritter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NbActiv4 medium improvement to Neurobasal/B27 increases neuron synapse densities and network spike rates on multielectrode arrays

(2008) Gregory J. Brewer et al.   JOURNAL OF NEUROSCIENCE METHODS

Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri

(2008) Feng Zhang et al.   NATURE NEUROSCIENCE

Channelrhodopsin-1 Initiates Phototaxis and Photophobic Responses in Chlamydomonas by Immediate Light-Induced Depolarization

(2008) P. Berthold et al.   PLANT CELL

Spectral Characteristics of the Photocycle of Channelrhodopsin-2 and Its Implication for Channel Function

(2007) Christian Bamann et al.   JOURNAL OF MOLECULAR BIOLOGY