Dimethyl Fumarate Inhibits Dendritic Cell Maturation via Nuclear Factor κB (NF-κB) and Extracellular Signal-regulated Kinase 1 and 2 (ERK1/2) and Mitogen Stress-activated Kinase 1 (MSK1) Signaling

TGF-β signaling via Smad4 drives IL-10 production in effector Th1 cells and reduces T-cell trafficking in EAE

(2011) David J. Huss et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells

(2011) Kamran Ghoreschi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Estriol Generates Tolerogenic Dendritic Cells In Vivo That Protect against Autoimmunity

(2011) T. L. Papenfuss et al.   JOURNAL OF IMMUNOLOGY

DC-SIGN ligation greatly affects dendritic cell differentiation from monocytes compromising their normal function

(2011) Urban Švajger et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Phase III success for Biogen's oral multiple sclerosis therapy

(2011)   NATURE REVIEWS DRUG DISCOVERY

Transforming Growth Factor-β1 Modulates Lipopolysaccharide-Induced Cytokine/Chemokine Production and Inhibits Nuclear Factor-κB, Extracellular Signal-Regulated Kinases and p38 Activation in Dendritic Cells in Mice

(2011) H.B. Mou et al.   TRANSPLANTATION PROCEEDINGS

The role of antigen presenting cells in multiple sclerosis

(2010) Emily M.L. Chastain et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Th1 versus Th17: Are T cell cytokines relevant in multiple sclerosis?

(2010) Amy E. Lovett-Racke et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

NF-κB Signaling: A Tale of Two Pathways in Skeletal Myogenesis

(2010) Nadine Bakkar et al.   PHYSIOLOGICAL REVIEWS

Nuclear NF- B p65 Phosphorylation at Serine 276 by Protein Kinase A Contributes to the Malignant Phenotype of Head and Neck Cancer

(2009) P. Arun et al.   CLINICAL CANCER RESEARCH

T-bet is essential for encephalitogenicity of both Th1 and Th17 cells

(2009) Yuhong Yang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Ser276 Phosphorylation of NF-kB p65 by MSK1 Controls SCF Expression in Inflammation

(2009) Laurent Reber et al.   PLoS One

Altered subcellular distribution of MSK1 induced by glucocorticoids contributes to NF-κB inhibition

(2008) Ilse M E Beck et al.   EMBO JOURNAL

MSK activation and physiological roles

(2008) J. Simon et al.   Frontiers in Bioscience-Landmark

NF-κB-dependent Transcriptional Activation in Lung Carcinoma Cells by Farnesol Involves p65/RelA(Ser276) Phosphorylation via the MEK-MSK1 Signaling Pathway

(2008) Joung Hyuck Joo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AKIP1 Enhances NF-κB-dependent Gene Expression by Promoting the Nuclear Retention and Phosphorylation of p65

(2008) Nan Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study

(2008) Ludwig Kappos et al.   LANCET