Rab5 Proteins Regulate Activation and Localization of Target of Rapamycin Complex 1

Amino Acid Signaling in TOR Activation

(2011) Joungmok Kim et al.   Annual Review of Biochemistry

Phospholipase D Mediates Nutrient Input to Mammalian Target of Rapamycin Complex 1 (mTORC1)

(2011) Limei Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Class III PI-3-kinase activates phospholipase D in an amino acid–sensing mTORC1 pathway

(2011) Mee-Sup Yoon et al.   JOURNAL OF CELL BIOLOGY

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase

(2011) R. Zoncu et al.   SCIENCE

Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids

(2010) Yasemin Sancak et al.   CELL

Regulation of mTORC1 by the Rab and Arf GTPases

(2010) Li Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Late Endosome is Essential for mTORC1 Signaling

(2010) Rory J. Flinn et al.   MOLECULAR BIOLOGY OF THE CELL

Genomic analysis of severe hypersensitivity to hygromycin B reveals linkage to vacuolar defects and new vacuolar gene functions in Saccharomyces cerevisiae

(2009) M. G. Banuelos et al.   CURRENT GENETICS

Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis

(2009) A. Huber et al.   GENES & DEVELOPMENT

The Vam6 GEF Controls TORC1 by Activating the EGO Complex

(2009) Matteo Binda et al.   MOLECULAR CELL

TOR regulation of AGC kinases in yeast and mammals

(2008) Estela Jacinto et al.   BIOCHEMICAL JOURNAL

The Endosomal Protein Appl1 Mediates Akt Substrate Specificity and Cell Survival in Vertebrate Development

(2008) Annette Schenck et al.   CELL

Insulin Stimulates Phosphatidylinositol 3-Phosphate Production via the Activation of Rab5

(2008) Irfan J. Lodhi et al.   MOLECULAR BIOLOGY OF THE CELL

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

Regulation of TORC1 by Rag GTPases in nutrient response

(2008) Eunjung Kim et al.   NATURE CELL BIOLOGY

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

(2008) Y. Sancak et al.   SCIENCE