Structure, Function, and Modulation of GABAAReceptors

A Closer Look at the High Affinity Benzodiazepine Binding Site on GABAA Receptors

(2012) Erwin Sigel et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Structural Link between γ-Aminobutyric Acid Type A (GABAA) Receptor Agonist Binding Site and Inner β-Sheet Governs Channel Activation and Allosteric Drug Modulation

(2012) Srinivasan P. Venkatachalan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unravelling the role of GABAAreceptor subtypes in distinct neurons and behaviour

(2012) Werner Sieghart   JOURNAL OF PHYSIOLOGY-LONDON

Diazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligands

(2012) Lars Richter et al.   Nature Chemical Biology

Characteristics of concatemeric GABAA receptors containing α4/δ subunits expressed in Xenopus oocytes

(2011) Hong-Jin Shu et al.   BRITISH JOURNAL OF PHARMACOLOGY

The GABAA Receptor  + - Interface: A Novel Target for Subtype Selective Drugs

(2011) J. Ramerstorfer et al.   JOURNAL OF NEUROSCIENCE

Principles of activation and permeation in an anion-selective Cys-loop receptor

(2011) Ryan E. Hibbs et al.   NATURE

Ligand-binding domain of an α7-nicotinic receptor chimera and its complex with agonist

(2011) Shu-Xing Li et al.   NATURE NEUROSCIENCE

The major central endocannabinoid directly acts at GABAA receptors

(2011) E. Sigel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatial and Temporal Dynamics in the Ionic Driving Force for GABAAReceptors

(2011) R. Wright et al.   NEURAL PLASTICITY

The role of Loop F in the activation of the GABA receptor

(2010) Alpa Khatri et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mutations in GABAAreceptor subunits associated with genetic epilepsies

(2010) Robert L. Macdonald et al.   JOURNAL OF PHYSIOLOGY-LONDON

Binding, activation and modulation of Cys-loop receptors

(2010) Paul S. Miller et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

RNA editing and its impact on GABAAreceptor function

(2009) Chammiran Daniel et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Unanticipated Structural and Functional Properties of δ-Subunit-containing GABAAReceptors

(2009) Kuldeep H. Kaur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Relative positioning of diazepam in the benzodiazepine-binding-pocket of GABAAreceptors

(2009) Kelly R. Tan et al.   JOURNAL OF NEUROCHEMISTRY

Structure of α6β3δ GABAAreceptors and their lack of ethanol sensitivity

(2009) Roland Baur et al.   JOURNAL OF NEUROCHEMISTRY

Docking of 1,4-Benzodiazepines in the  1/ 2 GABAA Receptor Modulator Site

(2009) D. Berezhnoy et al.   MOLECULAR PHARMACOLOGY

GABAA receptors are expressed and facilitate relaxation in airway smooth muscle

(2008) Kentaro Mizuta et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Covalent modification of GABAAreceptor isoforms by a diazepam analogue provides evidence for a novel benzodiazepine binding site that prevents modulation by these drugs

(2008) Roland Baur et al.   JOURNAL OF NEUROCHEMISTRY

GABA, a natural immunomodulator of T lymphocytes

(2008) Helen Bjurstöm et al.   JOURNAL OF NEUROIMMUNOLOGY

The promiscuous role of the epsilon subunit in GABAA receptor biogenesis

(2008) Karen A. Bollan et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

X-ray structure of a prokaryotic pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

GABAA receptor trafficking and its role in the dynamic modulation of neuronal inhibition

(2008) Tija C. Jacob et al.   NATURE REVIEWS NEUROSCIENCE

International Union of Pharmacology. LXX. Subtypes of  -Aminobutyric AcidA Receptors: Classification on the Basis of Subunit Composition, Pharmacology, and Function. Update

(2008) R. W. Olsen et al.   PHARMACOLOGICAL REVIEWS