Phosphatidylethanolamine Binding Is a Conserved Feature of Cyclotide-Membrane Interactions

Increased Exposure of Phosphatidylethanolamine on the Surface of Tumor Vascular Endothelium

(2015) Jason H. Stafford et al.   NEOPLASIA

Cyclotides, a Novel Ultrastable Polypeptide Scaffold for Drug Discovery

(2012) Andrew Gould et al.   CURRENT PHARMACEUTICAL DESIGN

Protease-Resistant Peptide Ligands from a Knottin Scaffold Library

(2011) Jennifer A. Getz et al.   ACS Chemical Biology

Virucidal activity of the dendrimer microbicide SPL7013 against HIV-1

(2011) Sushama Telwatte et al.   ANTIVIRAL RESEARCH

The Role of Conserved Glu Residue on Cyclotide Stability and Activity: A Structural and Functional Study of Kalata B12, a Naturally Occurring Glu to Asp Mutant

(2011) Conan K. L. Wang et al.   BIOCHEMISTRY

Cyclotide–membrane interactions: Defining factors of membrane binding, depletion and disruption

(2011) Robert Burman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds

(2011) L. Y. Chan et al.   BLOOD

A Synthetic Mirror Image of Kalata B1 Reveals that Cyclotide Activity Is Independent of a Protein Receptor

(2011) Lillian Sando et al.   CHEMBIOCHEM

Membrane interaction and antibacterial properties of two mildly cationic peptide diastereomers, bombinins H2 and H4, isolated from Bombina skin

(2011) Cristina Coccia et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Decoding the Membrane Activity of the Cyclotide Kalata B1

(2011) Sónia Troeira Henriques et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and Characterization of a New Family of Cell-penetrating Peptides

(2011) Laura Cascales et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular uptake of cyclotide MCoTI-I follows multiple endocytic pathways

(2011) Janette Contreras et al.   JOURNAL OF CONTROLLED RELEASE

Evolution of the PEBP Gene Family in Plants: Functional Diversification in Seed Plant Evolution

(2011) A. Karlgren et al.   PLANT PHYSIOLOGY

The cyclotide cycloviolacin O2 from Viola odorata has potent bactericidal activity against Gram-negative bacteria

(2010) M. Pranting et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Lysine-scanning Mutagenesis Reveals an Amendable Face of the Cyclotide Kalata B1 for the Optimization of Nematocidal Activity

(2010) Yen-Hua Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Escherichia coliCell Surface Perturbation and Disruption Induced by Antimicrobial Peptides BP100 and pepR

(2010) Carla S. Alves et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Antagonistic Pair of FT Homologs Mediates the Control of Flowering Time in Sugar Beet

(2010) P. A. Pin et al.   SCIENCE

Lantibiotics as probes for phosphatidylethanolamine

(2009) Ming Zhao   AMINO ACIDS

The Toxicity of Prion Protein Fragment PrP(106−126) is Not Mediated by Membrane Permeabilization as Shown by a M112W Substitution

(2009) Sónia Troeira Henriques et al.   BIOCHEMISTRY

Biosynthesis and Biological Screening of a Genetically Encoded Library Based on the Cyclotide MCoTI-I

(2009) Jeffrey Austin et al.   CHEMBIOCHEM

Cyclotides as templates in drug design

(2009) Sónia Troeira Henriques et al.   DRUG DISCOVERY TODAY

The Biological Activity of the Prototypic Cyclotide Kalata B1 Is Modulated by the Formation of Multimeric Pores

(2009) Yen-Hua Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Preparation and Properties of Asymmetric Vesicles That Mimic Cell Membranes

(2009) Hui-Ting Cheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Temperature-dependent hemolytic activity of membrane pore-forming peptide toxin, tolaasin

(2009) Kwang-Hyun Cho et al.   JOURNAL OF PEPTIDE SCIENCE

Cyclotides: Natural, Circular Plant Peptides that Possess Significant Activity against Gastrointestinal Nematode Parasites of Sheep†

(2008) Michelle L. Colgrave et al.   BIOCHEMISTRY

PrP(106-126) Does Not Interact with Membranes under Physiological Conditions

(2008) Sónia Troeira Henriques et al.   BIOPHYSICAL JOURNAL

Regulation of phospholipid asymmetry in the erythrocyte membrane

(2008) David L Daleke   CURRENT OPINION IN HEMATOLOGY

Backbone Cyclised Peptides from Plants Show Molluscicidal Activity against the Rice PestPomacea canaliculata(Golden Apple Snail)

(2008) Manuel Rey R. Plan et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Alanine Scanning Mutagenesis of the Prototypic Cyclotide Reveals a Cluster of Residues Essential for Bioactivity

(2008) Shane M. Simonsen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Engineering Stabilized Vascular Endothelial Growth Factor-A Antagonists: Synthesis, Structural Characterization, and Bioactivity of Grafted Analogues of Cyclotides

(2008) Sunithi Gunasekera et al.   JOURNAL OF MEDICINAL CHEMISTRY

Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances

(2008) Irith Wiegand et al.   Nature Protocols

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Plant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae

(2008) B. L. Barbeta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Quantitative Model for the All-or-None Permeabilization of Phospholipid Vesicles by the Antimicrobial Peptide Cecropin A

(2007) Sonia M. Gregory et al.   BIOPHYSICAL JOURNAL

Anti-HIV Cyclotides from the Chinese Medicinal HerbViola yedoensis

(2007) Conan K. L. Wang et al.   JOURNAL OF NATURAL PRODUCTS