标题
Hedgehog Secretion and Signal Transduction in Vertebrates
作者
关键词
-
出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 287, Issue 22, Pages 17905-17913
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2012-04-03
DOI
10.1074/jbc.r112.356006
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Gli Proteins in Development and Disease
- (2011) Chi-chung Hui et al. Annual Review of Cell and Developmental Biology
- Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube
- (2011) M. Tuson et al. DEVELOPMENT
- The Hedgehog-induced Smoothened conformational switch assembles a signaling complex that activates Fused by promoting its dimerization and phosphorylation
- (2011) Q. Shi et al. DEVELOPMENT
- Boc and Gas1 Each Form Distinct Shh Receptor Complexes with Ptch1 and Are Required for Shh-Mediated Cell Proliferation
- (2011) Luisa Izzi et al. DEVELOPMENTAL CELL
- Overlapping Roles and Collective Requirement for the Coreceptors GAS1, CDO, and BOC in SHH Pathway Function
- (2011) Benjamin L. Allen et al. DEVELOPMENTAL CELL
- Sonic Hedgehog Shedding Results in Functional Activation of the Solubilized Protein
- (2011) Stefanie Ohlig et al. DEVELOPMENTAL CELL
- Dual Phosphorylation of Suppressor of Fused (Sufu) by PKA and GSK3β Regulates Its Stability and Localization in the Primary Cilium
- (2011) Yan Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Three-part Signal Governs Differential Processing of Gli1 and Gli3 Proteins by the Proteasome
- (2011) Erin K. Schrader et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Processing and turnover of the Hedgehog protein in the endoplasmic reticulum
- (2011) Xin Chen et al. JOURNAL OF CELL BIOLOGY
- Complex interactions between genes controlling trafficking in primary cilia
- (2011) Polloneal Jymmiel R Ocbina et al. NATURE GENETICS
- Mechanisms and functions of Hedgehog signalling across the metazoa
- (2011) Philip W. Ingham et al. NATURE REVIEWS GENETICS
- Dispatched mediates Hedgehog basolateral release to form the long-range morphogenetic gradient in the Drosophila wing disk epithelium
- (2011) A. Callejo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sequential Phosphorylation of Smoothened Transduces Graded Hedgehog Signaling
- (2011) Y. Su et al. Science Signaling
- Sonic Hedgehog Dependent Phosphorylation by CK1α and GRK2 Is Required for Ciliary Accumulation and Activation of Smoothened
- (2011) Yongbin Chen et al. PLOS BIOLOGY
- Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors
- (2010) C. Wang et al. DEVELOPMENT
- Mechanism and evolution of cytosolic Hedgehog signal transduction
- (2010) C. W. Wilson et al. DEVELOPMENT
- Role of Lipid Metabolism in Smoothened Derepression in Hedgehog Signaling
- (2010) Amir Yavari et al. DEVELOPMENTAL CELL
- The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins
- (2010) E. W. Humke et al. GENES & DEVELOPMENT
- Genetic and biochemical definition of the Hedgehog receptor
- (2010) X. Zheng et al. GENES & DEVELOPMENT
- Interactions between Hedgehog proteins and their binding partners come into view
- (2010) P. A. Beachy et al. GENES & DEVELOPMENT
- G protein-coupled receptor kinase 2 promotes high-level Hedgehog signaling by regulating the active state of Smo through kinase-dependent and kinase-independent mechanisms in Drosophila
- (2010) Y. Chen et al. GENES & DEVELOPMENT
- A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu–Gli protein complexes
- (2010) Hanna Tukachinsky et al. JOURNAL OF CELL BIOLOGY
- Histone deacetylase and Cullin3–RENKCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation
- (2010) Gianluca Canettieri et al. NATURE CELL BIOLOGY
- The primary cilium: a signalling centre during vertebrate development
- (2010) Sarah C. Goetz et al. NATURE REVIEWS GENETICS
- Coordinated Translocation of Mammalian Gli Proteins and Suppressor of Fused to the Primary Cilium
- (2010) Huiqing Zeng et al. PLoS One
- Sufu recruits GSK3β for efficient processing of Gli3
- (2009) Yoshiaki Kise et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The Mammalian Cos2 Homolog Kif7 Plays an Essential Role in Modulating Hh Signal Transduction during Development
- (2009) Setsu Endoh-Yamagami et al. CURRENT BIOLOGY
- Suppressor of Fused inhibits mammalian Hedgehog signaling in the absence of cilia
- (2009) Jinping Jia et al. DEVELOPMENTAL BIOLOGY
- Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved
- (2009) M.-H. Chen et al. GENES & DEVELOPMENT
- Heparan Sulfate and Transglutaminase Activity Are Required for the Formation of Covalently Cross-linked Hedgehog Oligomers
- (2009) Tabea Dierker et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Full-length Unprocessed Hedgehog Protein Is an Active Signaling Molecule
- (2009) Robert Tokhunts et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Heparan Sulfate-modulated, Metalloprotease-mediated Sonic Hedgehog Release from Producing Cells
- (2009) Tabea Dierker et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lateral transport of Smoothened from the plasma membrane to the membrane of the cilium
- (2009) Ljiljana Milenkovic et al. JOURNAL OF CELL BIOLOGY
- Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP
- (2009) Benjamin Bishop et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling
- (2009) Ivan Bosanac et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling
- (2009) K. F. Liem et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus
- (2009) J. Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase
- (2009) Qing Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Kinesin Protein Kif7 Is a Critical Regulator of Gli Transcription Factors in Mammalian Hedgehog Signaling
- (2009) H. O.-L. Cheung et al. Science Signaling
- Nanoscale Organization of Hedgehog Is Essential for Long-Range Signaling
- (2008) Neha Vyas et al. CELL
- Phosphorylation of Gli2 by protein kinase A is required for Gli2 processing and degradation and the Sonic Hedgehog-regulated mouse development
- (2008) Yong Pan et al. DEVELOPMENTAL BIOLOGY
- Hhat Is a Palmitoylacyltransferase with Specificity forN-Palmitoylation of Sonic Hedgehog
- (2008) John A. Buglino et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla
- (2008) Jason S. McLellan et al. NATURE
- -Arrestin-Mediated Localization of Smoothened to the Primary Cilium
- (2008) J. J. Kovacs et al. SCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started