Mutations of the Ca2+-sensing Stromal Interaction Molecule STIM1 Regulate Ca2+Influx by Altered Oligomerization of STIM1 and by Destabilization of the Ca2+Channel Orai1

ORAI1 Ca2+ Channels Control Endothelin-1-Induced Mitogenesis and Melanogenesis in Primary Human Melanocytes

(2012) Hedwig Stanisz et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Immunodeficiency due to defects in store-operated calcium entry

(2011) Stefan Feske   Annals of the New York Academy of Sciences

Glu106in the Orai1 pore contributes to fast Ca2+-dependent inactivation and pH dependence of Ca2+release-activated Ca2+(CRAC) current

(2011) Nathan R. Scrimgeour et al.   BIOCHEMICAL JOURNAL

ORAI-mediated calcium influx in T cell proliferation, apoptosis and tolerance

(2011) Bin Qu et al.   CELL CALCIUM

Calcium microdomains at the immunological synapse: how ORAI channels, mitochondria and calcium pumps generate local calcium signals for efficient T-cell activation

(2011) Ariel Quintana et al.   EMBO JOURNAL

Stoichiometric requirements for trapping and gating of Ca2+release-activated Ca2+(CRAC) channels by stromal interaction molecule 1 (STIM1)

(2011) Paul J. Hoover et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysis

(2011) A. Maul-Pavicic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry

(2011) L. Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Basis of Calcium Signaling in Lymphocytes: STIM and ORAI

(2010) Patrick G. Hogan et al.   Annual Review of Immunology

Graded activation of CRAC channel by binding of different numbers of STIM1 to Orai1 subunits

(2010) Zhengzheng Li et al.   CELL RESEARCH

STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1

(2009) Chan Young Park et al.   CELL

Glycosylation in immune cell trafficking

(2009) Markus Sperandio et al.   IMMUNOLOGICAL REVIEWS

A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels

(2009) Martin Muik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Properties of Orai1 mediated store-operated current depend on the expression levels of STIM1 and Orai1 proteins

(2009) N. Scrimgeour et al.   JOURNAL OF PHYSIOLOGY-LONDON

SOAR and the polybasic STIM1 domains gate and regulate Orai channels

(2009) Joseph P. Yuan et al.   NATURE CELL BIOLOGY

Structural and Mechanistic Insights into STIM1-Mediated Initiation of Store-Operated Calcium Entry

(2008) Peter B. Stathopulos et al.   CELL

A novel mode of TRPML3 regulation by extracytosolic pH absent in the varitint-waddler phenotype

(2008) Hyun Jin Kim et al.   EMBO JOURNAL

Novel Role for STIM1 as a Trigger for Calcium Influx Factor Production

(2008) Peter Csutora et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction

(2008) David Varga-Szabo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hair Loss and Defective T- and B-Cell Function in Mice Lacking ORAI1

(2008) Y. Gwack et al.   MOLECULAR AND CELLULAR BIOLOGY

Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance

(2008) Masatsugu Oh-hora et al.   NATURE IMMUNOLOGY

Orai1 and STIM1 move to the immunological synapse and are up-regulated during T cell activation

(2008) M. I. Lioudyno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA