Calcium microdomains at the immunological synapse: how ORAI channels, mitochondria and calcium pumps generate local calcium signals for efficient T-cell activation

The mitochondrial fission factor dynamin-related protein 1 modulates T-cell receptor signalling at the immune synapse

(2011) Francesc Baixauli et al.   EMBO JOURNAL

Cooperativeness of Orai Cytosolic Domains Tunes Subtype-specific Gating

(2011) Irene Frischauf et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Leucine Zipper EF Hand-containing Transmembrane Protein 1 (Letm1) and Uncoupling Proteins 2 and 3 (UCP2/3) Contribute to Two Distinct Mitochondrial Ca2+Uptake Pathways

(2011) Markus Waldeck-Weiermair et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nonsteroidal Anti-inflammatory Drugs Inhibit Vascular Smooth Muscle Cell Proliferation by Enabling the Ca2+-dependent Inactivation of Calcium Release-activated Calcium/Orai Channels Normally Prevented by Mitochondria

(2011) Eva Muñoz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective Activation of the Transcription Factor NFAT1 by Calcium Microdomains near Ca2+Release-activated Ca2+(CRAC) Channels

(2011) Pulak Kar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter

(2011) Joshua M. Baughman et al.   NATURE

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

(2011) Diego De Stefani et al.   NATURE

Adhesion shapes T cells for prompt and sustained T-cell receptor signalling

(2010) Rita Lucia Contento et al.   EMBO JOURNAL

n-3 Polyunsaturated Fatty Acids Suppress Mitochondrial Translocation to the Immunologic Synapse and Modulate Calcium Signaling in T Cells

(2010) R. Yog et al.   JOURNAL OF IMMUNOLOGY

Ca2+ Hot Spots on the Mitochondrial Surface Are Generated by Ca2+ Mobilization from Stores, but Not by Activation of Store-Operated Ca2+ Channels

(2010) Marta Giacomello et al.   MOLECULAR CELL

A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells

(2010) Sonal Srikanth et al.   NATURE CELL BIOLOGY

STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1

(2009) Chan Young Park et al.   CELL

Measuring mitochondrial and cytoplasmic Ca2+ in EGFP expressing cells with a low-affinity Calcium Ruby and its dextran conjugate

(2009) Camilla Luccardini et al.   CELL CALCIUM

Store-operated Ca2+ influx and subplasmalemmal mitochondria

(2009) Marek K. Korzeniowski et al.   CELL CALCIUM

Mitochondria Positioning Controls Local Calcium Influx in T Cells

(2009) Christian Schwindling et al.   JOURNAL OF IMMUNOLOGY

STIM1 and calmodulin interact with Orai1 to induce Ca2+-dependent inactivation of CRAC channels

(2009) F. M. Mullins et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calmodulin Binding to the Polybasic C-Termini of STIM Proteins Involved in Store-Operated Calcium Entry†

(2008) Mikael C. Bauer et al.   BIOCHEMISTRY

The role of mitochondrial potential in control of calcium signals involved in cell proliferation

(2008) Ruth A. Valero et al.   CELL CALCIUM

Morphological changes of T cells following formation of the immunological synapse modulate intracellular calcium signals

(2008) Ariel Quintana et al.   CELL CALCIUM

Calcium signaling in lymphocytes

(2008) Masatsugu Oh-hora et al.   CURRENT OPINION IN IMMUNOLOGY

T-cell activation through immunological synapses and kinapses

(2008) Michael L. Dustin   IMMUNOLOGICAL REVIEWS

Re-organization of mitochondria at the NK cell immune synapse

(2008) Edgar Abarca-Rojano et al.   IMMUNOLOGY LETTERS

Dynamic Movement of the Calcium Sensor STIM1 and the Calcium Channel Orai1 in Activated T-Cells: Puncta and Distal Caps

(2008) Valarie A. Barr et al.   MOLECULAR BIOLOGY OF THE CELL

Orai1 and STIM1 move to the immunological synapse and are up-regulated during T cell activation

(2008) M. I. Lioudyno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase

(2008) M. Saotome et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA