Phosphorylation of FOXO3a on Ser-7 by p38 Promotes Its Nuclear Localization in Response to Doxorubicin

Cisplatin Induces Cytotoxicity through the Mitogen-Activated Protein Kinase Pathways ana Activating Transcription Factor 3

(2015) Carly St. Germain et al.   NEOPLASIA

p34SEI-1inhibits ROS-induced cell death through suppression of ASK1

(2011) Seung-Woo Hong et al.   CANCER BIOLOGY & THERAPY

A pathway from JNK through decreased ERK and Akt activities for FOXO3a nuclear translocation in response to UV irradiation

(2011) Xianwang Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

ATM and p53 Regulate FOXM1 Expression via E2F in Breast Cancer Epirubicin Treatment and Resistance

(2011) J. Millour et al.   MOLECULAR CANCER THERAPEUTICS

The Extending Network of FOXO Transcriptional Target Genes

(2010) Kristan E. van der Vos et al.   ANTIOXIDANTS & REDOX SIGNALING

Sense and Sensitivity: FOXO and ROS in Cancer Development and Treatment

(2010) Stephen S. Myatt et al.   ANTIOXIDANTS & REDOX SIGNALING

Mechanisms and functions of p38 MAPK signalling

(2010) Ana Cuadrado et al.   BIOCHEMICAL JOURNAL

Foxo3a expression and acetylation regulate cancer cell growth and sensitivity to cisplatin

(2010) Masaki Shiota et al.   CANCER SCIENCE

The AMPK-FoxO3A axis as a target for cancer treatment

(2010) Fulvio Chiacchiera et al.   CELL CYCLE

FOXM1 Confers Acquired Cisplatin Resistance in Breast Cancer Cells

(2010) J. M.-M. Kwok et al.   MOLECULAR CANCER RESEARCH

Constitutively Nuclear FOXO3a Localization Predicts Poor Survival and Promotes Akt Phosphorylation in Breast Cancer

(2010) Jie Chen et al.   PLoS One

A New Fork for Clinical Application: Targeting Forkhead Transcription Factors in Cancer

(2009) J.-Y. Yang et al.   CLINICAL CANCER RESEARCH

Multilayered control of gene expression by stress-activated protein kinases

(2009) Eulàlia de Nadal et al.   EMBO JOURNAL

Potentiation of paclitaxel-induced apoptosis by galectin-13 overexpression via activation of Ask-1-p38-MAP kinase and JNK/SAPK pathways and suppression of Akt and ERK1/2 activation in U-937 human macrophage cells

(2009) Arpad Boronkai et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Target Gene Specificity of USF-1 Is Directed via p38-mediated Phosphorylation-dependent Acetylation

(2009) Sébastien Corre et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemical Interrogation of FOXO3a Nuclear Translocation Identifies Potent and Selective Inhibitors of Phosphoinositide 3-Kinases

(2009) Wolfgang Link et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gefitinib (Iressa) represses FOXM1 expression via FOXO3a in breast cancer

(2009) U. B. McGovern et al.   MOLECULAR CANCER THERAPEUTICS

Overcoming Drug Resistance in Patients with Metastatic Breast Cancer

(2009) Serena T Wong et al.   PHARMACOTHERAPY

p38MAPK: stress responses from molecular mechanisms to therapeutics

(2009) Lydia R. Coulthard et al.   TRENDS IN MOLECULAR MEDICINE

p38 MAP kinase mediates arsenite-induced apoptosis through FOXO3a activation and induction of Bim transcription

(2008) Beibei Cai et al.   APOPTOSIS

Acetylation of FOXO3a transcription factor in response to imatinib of chronic myeloid leukemia

(2008) P Corrado et al.   LEUKEMIA

The Forkhead Transcription Factor FOXO3a Increases Phosphoinositide-3 Kinase/Akt Activity in Drug-Resistant Leukemic Cells through Induction of PIK3CA Expression

(2008) R. C.-Y. Hui et al.   MOLECULAR AND CELLULAR BIOLOGY

Thiostrepton selectively targets breast cancer cells through inhibition of forkhead box M1 expression

(2008) J. M-M. Kwok et al.   MOLECULAR CANCER THERAPEUTICS

Doxorubicin activates FOXO3a to induce the expression of multidrug resistance gene ABCB1 (MDR1) in K562 leukemic cells

(2008) R. C-Y. Hui et al.   MOLECULAR CANCER THERAPEUTICS

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

(2008) Jer-Yen Yang et al.   NATURE CELL BIOLOGY

Many forks in the path: cycling with FoxO

(2008) K K Ho et al.   ONCOGENE