Lysine-specific Demethylase 2B (KDM2B)-let-7-Enhancer of Zester Homolog 2 (EZH2) Pathway Regulates Cell Cycle Progression and Senescence in Primary Cells

KDM2b/JHDM1b, an H3K36me2-specific demethylase, is required for initiation and maintenance of acute myeloid leukemia

(2011) J. He et al.   BLOOD

MiR-26a Inhibits Cell Growth and Tumorigenesis of Nasopharyngeal Carcinoma through Repression of EZH2

(2011) J. Lu et al.   CANCER RESEARCH

Deregulated expression of miR-26a and Ezh2 in Rhabdomyosarcoma

(2011) Roberta Ciarapica et al.   CELL CYCLE

Fbxl10/Kdm2b deficiency accelerates neural progenitor cell death and leads to exencephaly

(2011) Tsuyoshi Fukuda et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101 and miR-98

(2011) N M Alajez et al.   Cell Death & Disease

CpG Islands Recruit a Histone H3 Lysine 36 Demethylase

(2010) Neil P. Blackledge et al.   MOLECULAR CELL

Aging and microRNA expression in human skeletal muscle: a microarray and bioinformatics analysis

(2010) Micah J. Drummond et al.   PHYSIOLOGICAL GENOMICS

MicroRNA Let-7a Inhibits Proliferation of Human Prostate Cancer Cells In Vitro and In Vivo by Targeting E2F2 and CCND2

(2010) Qingchuan Dong et al.   PLoS One

The Putative Tumor Suppressor microRNA-101 Modulates the Cancer Epigenome by Repressing the Polycomb Group Protein EZH2

(2009) J. M. Friedman et al.   CANCER RESEARCH

Raptor Binds the SAIN (Shc and IRS-1 NPXY Binding) Domain of Insulin Receptor Substrate-1 (IRS-1) and Regulates the Phosphorylation of IRS-1 at Ser-636/639 by mTOR

(2009) Alexandros Tzatsos   JOURNAL OF BIOLOGICAL CHEMISTRY

let-7Overexpression Leads to an Increased Fraction of Cells in G2/M, Direct Down-regulation of Cdc34, and Stabilization of Wee1 Kinase in Primary Fibroblasts

(2009) Aster Legesse-Miller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mir-214-Dependent Regulation of the Polycomb Protein Ezh2 in Skeletal Muscle and Embryonic Stem Cells

(2009) Aster H. Juan et al.   MOLECULAR CELL

BCOR regulates mesenchymal stem cell function by epigenetic mechanisms

(2009) Zhipeng Fan et al.   NATURE CELL BIOLOGY

Anchorage-independent cell growth signature identifies tumors with metastatic potential

(2009) S Mori et al.   ONCOGENE

Ndy1/KDM2B immortalizes mouse embryonic fibroblasts by repressing theInk4a/Arflocus

(2009) Alexandros Tzatsos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MYC stimulates EZH2 expression by repression of its negative regulator miR-26a

(2008) S. Sander et al.   BLOOD

Hmga2 Promotes Neural Stem Cell Self-Renewal in Young but Not Old Mice by Reducing p16Ink4a and p19Arf Expression

(2008) Jinsuke Nishino et al.   CELL

Senescence of Activated Stellate Cells Limits Liver Fibrosis

(2008) Valery Krizhanovsky et al.   CELL

Ink4a/Arf Regulation by let-7b and Hmga2: A Genetic Pathway Governing Stem Cell Aging

(2008) Alexandros Tzatsos et al.   Cell Stem Cell

dKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing

(2008) A. Lagarou et al.   GENES & DEVELOPMENT

The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15Ink4b

(2008) Jin He et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Replicative Senescence of Mesenchymal Stem Cells: A Continuous and Organized Process

(2008) Wolfgang Wagner et al.   PLoS One

Members of a family of JmjC domain-containing oncoproteins immortalize embryonic fibroblasts via a JmjC domain-dependent process

(2008) R. Pfau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic Loss of microRNA-101 Leads to Overexpression of Histone Methyltransferase EZH2 in Cancer

(2008) S. Varambally et al.   SCIENCE

The let-7 family of microRNAs

(2008) Sarah Roush et al.   TRENDS IN CELL BIOLOGY

Human Multipotent Stromal Cells Undergo Sharp Transition from Division to Development in Culture

(2007) Benjamin L. Larson et al.   STEM CELLS