Thiazolyl Peptide Antibiotic Biosynthesis: A Cascade of Post-translational Modifications on Ribosomal Nascent Proteins

Identification and Analysis of the Biosynthetic Gene Cluster Encoding the Thiopeptide Antibiotic Cyclothiazomycin in Streptomyces hygroscopicus 10-22

(2010) J. Wang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Programming of Erythromycin Biosynthesis by a Modular Polyketide Synthase

(2010) David E. Cane   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxytetracycline Biosynthesis

(2010) Lauren B. Pickens et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Daptomycin, a Bacterial Lipopeptide Synthesized by a Nonribosomal Machinery

(2010) Lars Robbel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Manipulation of Thiocillin Variants by Prepeptide Gene Replacement: Structure, Conformation, and Activity of Heterocycle Substitution Mutants

(2010) Albert A. Bowers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Natural Products Version 2.0: Connecting Genes to Molecules

(2010) Christopher T. Walsh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nosiheptide Biosynthesis Featuring a Unique Indole Side Ring Formation on the Characteristic Thiopeptide Framework

(2009) Yi Yu et al.   ACS Chemical Biology

Total Synthesis and Stereochemical Assignment of Micrococcin P1

(2009) David Lefranc et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Identification of Distinct Thiopeptide-Antibiotic Precursor Lead Compounds Using Translation Machinery Assays

(2009) Agata L. Starosta et al.   CHEMISTRY & BIOLOGY

Thiopeptide Biosynthesis Featuring Ribosomally Synthesized Precursor Peptides and Conserved Posttranslational Modifications

(2009) Rijing Liao et al.   CHEMISTRY & BIOLOGY

Nocardithiocin, a novel thiopeptide antibiotic, produced by pathogenic Nocardia pseudobrasiliensis IFM 0757

(2009) Akira Mukai et al.   JOURNAL OF ANTIBIOTICS

Thiostrepton Biosynthesis: Prototype for a New Family of Bacteriocins

(2009) Wendy L. Kelly et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ribosomally Synthesized Thiopeptide Antibiotics Targeting Elongation Factor Tu

(2009) Rowan P. Morris et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Generation of Thiocillin Variants by Prepeptide Gene Replacement and in Vivo Processing byBacillus cereus

(2009) Michael G. Acker et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ribosomal peptide natural products: bridging the ribosomal and nonribosomal worlds

(2009) John A. McIntosh et al.   NATURAL PRODUCT REPORTS

Follow the leader: the use of leader peptides to guide natural product biosynthesis

(2009) Trent J Oman et al.   Nature Chemical Biology

Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin

(2009) Laura C. Wieland Brown et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Elongation in translation as a dynamic interaction among the ribosome, tRNA, and elongation factors EF-G and EF-Tu

(2009) Xabier Agirrezabala et al.   QUARTERLY REVIEWS OF BIOPHYSICS

How Nature Morphs Peptide Scaffolds into Antibiotics

(2008) Elizabeth M. Nolan et al.   CHEMBIOCHEM

A Fluorescent Probe for the 70 S-Ribosomal GTPase-Associated Center

(2008) Sebastian Schoof et al.   CHEMBIOCHEM

Total syntheses of amythiamicins A, B and C

(2008) K. C. Nicolaou et al.   CHEMICAL COMMUNICATIONS

Concise Total Synthesis of the Thiazolyl Peptide Antibiotic GE2270 A

(2008) Oscar Delgado et al.   CHEMISTRY-A EUROPEAN JOURNAL

Total Synthesis of Thiopeptide Antibiotics GE2270A, GE2270T, and GE2270C1

(2008) K. C. Nicolaou et al.   Chemistry-An Asian Journal

Translational Regulation via L11: Molecular Switches on the Ribosome Turned On and Off by Thiostrepton and Micrococcin

(2008) Joerg M. Harms et al.   MOLECULAR CELL

Total biosynthesis: in vitro reconstitution of polyketide and nonribosomal peptide pathways

(2008) Elizabeth S. Sattely et al.   NATURAL PRODUCT REPORTS

A global assembly line for cyanobactins

(2008) Mohamed S Donia et al.   Nature Chemical Biology

Intramolecular cyclizations of polyketide biosynthesis: mining for a “Diels–Alderase”?

(2008) Wendy L. Kelly   ORGANIC & BIOMOLECULAR CHEMISTRY