标题
The molecular era of the mitochondrial calcium uniporter
作者
关键词
-
出版物
NATURE REVIEWS MOLECULAR CELL BIOLOGY
Volume 16, Issue 9, Pages 545-553
出版商
Springer Nature
发表日期
2015-08-19
DOI
10.1038/nrm4039
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- CCDC90A (MCUR1) Is a Cytochrome c Oxidase Assembly Factor and Not a Regulator of the Mitochondrial Calcium Uniporter
- (2015) Vincent Paupe et al. Cell Metabolism
- Ca2+signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+uniporter geneMCU
- (2015) Santhanam Shanmughapriya et al. Science Signaling
- The mitochondrial uniporter controls fight or flight heart rate increases
- (2015) Yuejin Wu et al. Nature Communications
- Mitochondrial Ca2+-dependent NLRP3 activation exacerbates the Pseudomonas aeruginosa-driven inflammatory response in cystic fibrosis
- (2015) Alessandro Rimessi et al. Nature Communications
- The Mitochondrial Calcium Uniporter Controls Skeletal Muscle Trophism In Vivo
- (2015) Cristina Mammucari et al. Cell Reports
- Ca2+signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+uniporter geneMCU
- (2015) Santhanam Shanmughapriya et al. Science Signaling
- Release of Ca2+ from the endoplasmic reticulum and its subsequent influx into mitochondria trigger celastrol-induced paraptosis in cancer cells
- (2015) Mi Jin Yoon et al. Oncotarget
- Unresolved questions from the analysis of mice lacking MCU expression
- (2014) Elizabeth Murphy et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The uniporter: From newly identified parts to function
- (2014) Kimberli J. Kamer et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Development and Applications of CRISPR-Cas9 for Genome Engineering
- (2014) Patrick D. Hsu et al. CELL
- C. elegans Epidermal Wounding Induces a Mitochondrial ROS Burst that Promotes Wound Repair
- (2014) Suhong Xu et al. DEVELOPMENTAL CELL
- Structural and mechanistic insights into MICU1 regulation of mitochondrial calcium uptake
- (2014) L. Wang et al. EMBO JOURNAL
- MICU1 and MICU2 play nonredundant roles in the regulation of the mitochondrial calcium uniporter
- (2014) K. J. Kamer et al. EMBO REPORTS
- IP3-mediated STIM1 oligomerization requires intact mitochondrial Ca2+ uptake
- (2014) A. T. Deak et al. JOURNAL OF CELL SCIENCE
- SLC25A23 augments mitochondrial Ca2+ uptake, interacts with MCU, and induces oxidative stress–mediated cell death
- (2014) Nicholas E. Hoffman et al. MOLECULAR BIOLOGY OF THE CELL
- Proteomic Mapping of the Human Mitochondrial Intermembrane Space in Live Cells via Ratiometric APEX Tagging
- (2014) Victoria Hung et al. MOLECULAR CELL
- MICU1 and MICU2 Finely Tune the Mitochondrial Ca2+ Uniporter by Exerting Opposite Effects on MCU Activity
- (2014) Maria Patron et al. MOLECULAR CELL
- Directed evolution of APEX2 for electron microscopy and proximity labeling
- (2014) Stephanie S Lam et al. NATURE METHODS
- Mitochondrial Calcium Uniporter Activity Is Dispensable for MDA-MB-231 Breast Carcinoma Cell Survival
- (2014) Duane D. Hall et al. PLoS One
- Mitochondrial Calcium Uniporter MCU Supports Cytoplasmic Ca2+ Oscillations, Store-Operated Ca2+ Entry and Ca2+-Dependent Gene Expression in Response to Receptor Stimulation
- (2014) Krishna Samanta et al. PLoS One
- Reconstitution of the mitochondrial calcium uniporter in yeast
- (2014) E. Kovacs-Bogdan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Endoplasmic reticulum calcium release through ITPR2 channels leads to mitochondrial calcium accumulation and senescence
- (2014) Clotilde Wiel et al. Nature Communications
- MICU1 Controls Both the Threshold and Cooperative Activation of the Mitochondrial Ca2+ Uniporter
- (2013) György Csordás et al. Cell Metabolism
- The mitochondrial calcium uniporter is a multimer that can include a dominant-negative pore-forming subunit
- (2013) Anna Raffaello et al. EMBO JOURNAL
- The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation
- (2013) K. Triantafilou et al. JOURNAL OF CELL SCIENCE
- The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter
- (2013) Xin Pan et al. NATURE CELL BIOLOGY
- Loss-of-function mutations in MICU1 cause a brain and muscle disorder linked to primary alterations in mitochondrial calcium signaling
- (2013) Clare V Logan et al. NATURE GENETICS
- MICU2, a Paralog of MICU1, Resides within the Mitochondrial Uniporter Complex to Regulate Calcium Handling
- (2013) Molly Plovanich et al. PLoS One
- EMRE Is an Essential Component of the Mitochondrial Calcium Uniporter Complex
- (2013) Y. Sancak et al. SCIENCE
- ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering
- (2013) Thomas Gaj et al. TRENDS IN BIOTECHNOLOGY
- Bcl-wav and the mitochondrial calcium uniporter drive gastrula morphogenesis in zebrafish
- (2013) Julien Prudent et al. Nature Communications
- MICU1 Motifs Define Mitochondrial Calcium Uniporter Binding and Activity
- (2013) Nicholas E. Hoffman et al. Cell Reports
- MCU encodes the pore conducting mitochondrial calcium currents
- (2013) Dipayan Chaudhuri et al. eLife
- MICU1 Is an Essential Gatekeeper for MCU-Mediated Mitochondrial Ca2+ Uptake that Regulates Cell Survival
- (2012) Karthik Mallilankaraman et al. CELL
- Downregulation of the Mitochondrial Calcium Uniporter by Cancer-Related miR-25
- (2012) Saverio Marchi et al. CURRENT BIOLOGY
- Mitochondrial Ca2+Uptake 1 (MICU1) and Mitochondrial Ca2+Uniporter (MCU) Contribute to Metabolism-Secretion Coupling in Clonal Pancreatic β-Cells
- (2012) Muhammad Rizwan Alam et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial disorders as windows into an ancient organelle
- (2012) Scott B. Vafai et al. NATURE
- MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism
- (2012) Karthik Mallilankaraman et al. NATURE CELL BIOLOGY
- Frequency-dependent mitochondrial Ca2+ accumulation regulates ATP synthesis in pancreatic β cells
- (2012) Andrei I. Tarasov et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Mitochondrial Ca2+ uptake contributes to buffering cytoplasmic Ca2+ peaks in cardiomyocytes
- (2012) I. Drago et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evolutionary Diversity of the Mitochondrial Calcium Uniporter
- (2012) A. G. Bick et al. SCIENCE
- Activity of the mitochondrial calcium uniporter varies greatly between tissues
- (2012) Francesca Fieni et al. Nature Communications
- Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter
- (2011) Joshua M. Baughman et al. NATURE
- A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter
- (2011) Diego De Stefani et al. NATURE
- MICU1 encodes a mitochondrial EF hand protein required for Ca2+ uptake
- (2010) Fabiana Perocchi et al. NATURE
- NCLX is an essential component of mitochondrial Na+/Ca2+ exchange
- (2009) R. Palty et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genome-Wide RNAi Screen Identifies Letm1 as a Mitochondrial Ca2+/H+ Antiporter
- (2009) D. Jiang et al. SCIENCE
- A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology
- (2008) David J. Pagliarini et al. CELL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started