Modulation of p53 during bacterial infections

Helicobacter pylori bacteria alter the p53 stress response via ERK-HDM2 pathway

(2015) Vikas Bhardwaj et al.   Oncotarget

EphrinA2 Receptor (EphA2) Is an Invasion and Intracellular Signaling Receptor for Chlamydia trachomatis

(2015) Prema Subbarayal et al.   PLoS Pathogens

Listeria monocytogenesinduces host DNA damage and delays the host cell cycle to promote infection

(2014) Elsa Leitão et al.   CELL CYCLE

Shigellareroutes host cell central metabolism to obtain high-flux nutrient supply for vigorous intracellular growth

(2014) David Kentner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chlamydia infection depends on a functional MDM2-p53 axis

(2014) Erik González et al.   Nature Communications

Tumor Suppressor p53 Alters Host Cell Metabolism to Limit Chlamydia trachomatis Infection

(2014) Christine Siegl et al.   Cell Reports

Listeria monocytogenes Dampens the DNA Damage Response

(2014) Ascel Samba-Louaka et al.   PLoS Pathogens

The Role of PI3K/Akt/mTOR Signaling in Gastric Carcinoma

(2014) Tasuku Matsuoka et al.   Cancers

p53 Acetylation: Regulation and Consequences

(2014) Sara Reed et al.   Cancers

Chlamydia Infection Promotes Host DNA Damage and Proliferation but Impairs the DNA Damage Response

(2013) Cindrilla Chumduri et al.   Cell Host & Microbe

Enhanced expression of activation-induced cytidine deaminase in human gastric mucosa infected by Helicobacter pylori and its decrease following eradication

(2013) Naoyoshi Nagata et al.   JOURNAL OF GASTROENTEROLOGY

Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

(2013) Shin Yoshimoto et al.   NATURE

Suppression of Host p53 Is Critical for Plasmodium Liver-Stage Infection

(2013) Alexis Kaushansky et al.   Cell Reports

Parallel Exploitation of Diverse Host Nutrients Enhances Salmonella Virulence

(2013) Benjamin Steeb et al.   PLoS Pathogens

SIRT6 Puts Cancer Metabolism in the Driver’s Seat

(2012) Costas A. Lyssiotis et al.   CELL

The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism

(2012) Carlos Sebastián et al.   CELL

To Die or Not to Die—Shigella Has an Answer

(2012) Thomas Rudel   Cell Host & Microbe

Calpain Activation by the Shigella flexneri Effector VirA Regulates Key Steps in the Formation and Life of the Bacterium's Epithelial Niche

(2012) Jean Bergounioux et al.   Cell Host & Microbe

Interactions between the tumor suppressor p53 and immune responses

(2012) Daniel Menendez et al.   CURRENT OPINION IN ONCOLOGY

Neisseria gonorrhoeae infection causes DNA damage and affects the expression of p21, p27 and p53 in non-tumor epithelial cells

(2012) Katarina Vielfort et al.   JOURNAL OF CELL SCIENCE

Imbalanced Oxidative Stress Causes Chlamydial Persistence during Non-Productive Human Herpes Virus Co-Infection

(2012) Bhupesh K. Prusty et al.   PLoS One

Pathogenic bacterium Helicobacter pylori alters the expression profile of p53 protein isoforms and p53 response to cellular stresses

(2012) J. Wei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Translational approaches targeting the p53 pathway for anti-cancer therapy

(2011) Frank Essmann et al.   BRITISH JOURNAL OF PHARMACOLOGY

p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase

(2011) Peng Jiang et al.   NATURE CELL BIOLOGY

Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells

(2011) I. M. Toller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Helicobacter pylori cytotoxin-associated gene A (CagA) subverts the apoptosis-stimulating protein of p53 (ASPP2) tumor suppressor pathway of the host

(2011) L. Buti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Salmonella typhimurium infection increases p53 acetylation in intestinal epithelial cells

(2010) Shaoping Wu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The bacterial effectors EspG and EspG2 induce a destructive calpain activity that is kept in check by the co-delivered Tir effector

(2010) Paul Dean et al.   CELLULAR MICROBIOLOGY

Restoring p53 tumor suppressor activity as an anticancer therapeutic strategy

(2010) Jesse D Martinez   Future Oncology

Regulation of p53 Tumor Suppressor by Helicobacter pylori in Gastric Epithelial Cells

(2010) Jinxiong Wei et al.   GASTROENTEROLOGY

Cytoplasmic sequestration of p53 promotes survival in leukocytes transformed by Theileria

(2010) D Haller et al.   ONCOGENE

Shigella Induces Mitochondrial Dysfunction and Cell Death in Nonmyleoid Cells

(2009) Leticia A.M. Carneiro et al.   Cell Host & Microbe

Spa15 of Shigella flexneri Is Secreted through the Type III Secretion System and Prevents Staurosporine-Induced Apoptosis

(2009) C. S. Faherty et al.   INFECTION AND IMMUNITY

p53 Attenuates Lipopolysaccharide-Induced NF- B Activation and Acute Lung Injury

(2009) G. Liu et al.   JOURNAL OF IMMUNOLOGY

Degradation of Phosphorylated p53 by Viral Protein-ECS E3 Ligase Complex

(2009) Yoshitaka Sato et al.   PLoS Pathogens

p53's mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity

(2008) Sonja Wolff et al.   CELL RESEARCH

Risk factors for a serous cancer precursor (“p53 signature”) in women with inherited BRCA mutations

(2008) Aasia Saleemuddin et al.   GYNECOLOGIC ONCOLOGY

p53 Regulates Toll-Like Receptor 3 Expression and Function in Human Epithelial Cell Lines

(2008) M. Taura et al.   MOLECULAR AND CELLULAR BIOLOGY

Mcl-1 Is a Key Regulator of Apoptosis Resistance in Chlamydia trachomatis-Infected Cells

(2008) Krishnaraj Rajalingam et al.   PLoS One