标题
Chylomicronaemia—current diagnosis and future therapies
作者
关键词
-
出版物
Nature Reviews Endocrinology
Volume 11, Issue 6, Pages 352-362
出版商
Springer Nature
发表日期
2015-03-03
DOI
10.1038/nrendo.2015.26
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Apolipoprotein C-II Tuzla: A novel large deletion in APOC2 caused by Alu-Alu homologous recombination in an infant with apolipoprotein C-II deficiency
- (2015) Minoru Okubo et al. CLINICA CHIMICA ACTA
- Homozygosity for a partial deletion of apoprotein A-V signal peptide results in intracellular missorting of the protein and chylomicronemia in a breast-fed infant
- (2014) Kirstin Albers et al. ATHEROSCLEROSIS
- Therapeutic Strategies for Metabolic Diseases: Small-Molecule Diacylglycerol Acyltransferase (DGAT) Inhibitors
- (2014) Ravi Naik et al. ChemMedChem
- Lomitapide and Mipomersen
- (2014) Daniel J. Rader et al. CIRCULATION
- Postprandial lipemia as a cardiometabolic risk factor
- (2014) Angela Pirillo et al. CURRENT MEDICAL RESEARCH AND OPINION
- Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society
- (2014) M. Cuchel et al. EUROPEAN HEART JOURNAL
- Current knowledge of hypertriglyceridemic pancreatitis
- (2014) Pedro Valdivielso et al. European Journal of Internal Medicine
- Familial chylomicronemia syndrome related chronic pancreatitis: a single-center study
- (2014) Gurhan Sisman et al. Hepatobiliary & Pancreatic Diseases International
- Multimerization of Glycosylphosphatidylinositol-anchored High Density Lipoprotein-binding Protein 1 (GPIHBP1) and Familial Chylomicronemia from a Serine-to-Cysteine Substitution in GPIHBP1 Ly6 Domain
- (2014) Wanee Plengpanich et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Extreme hypertriglyceridemia managed with insulin
- (2014) Moe Thuzar et al. Journal of Clinical Lipidology
- Genotype-phenotype relationships in patients with type I hyperlipoproteinemia
- (2014) Neema Chokshi et al. Journal of Clinical Lipidology
- LipidSeq: a next-generation clinical resequencing panel for monogenic dyslipidemias
- (2014) Christopher T. Johansen et al. JOURNAL OF LIPID RESEARCH
- Loss-of-Function Mutations in APOC3 and Risk of Ischemic Vascular Disease
- (2014) Anders Berg Jørgensen et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeting APOC3 in the Familial Chylomicronemia Syndrome
- (2014) Daniel Gaudet et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeted delivery of antisense oligonucleotides to hepatocytes using triantennaryN-acetyl galactosamine improves potency 10-fold in mice
- (2014) Thazha P. Prakash et al. NUCLEIC ACIDS RESEARCH
- Novel Treatments for Familial Hypercholesterolemia: Pharmacogenetics at Work
- (2014) Jeffrey A. Marbach et al. PHARMACOTHERAPY
- Recent advances in pharmacotherapy for hypertriglyceridemia
- (2014) Amirhossein Sahebkar et al. PROGRESS IN LIPID RESEARCH
- Therapeutic apheresis for severe hypertriglyceridemia in pregnancy
- (2013) Rafet Basar et al. ARCHIVES OF GYNECOLOGY AND OBSTETRICS
- A three month-old infant with severe hyperchylomicronemia: Molecular diagnosis and extracorporeal treatment
- (2013) Claudia Stefanutti et al. ATHEROSCLEROSIS SUPPLEMENTS
- Treatment options for hypertriglyceridemia: From risk reduction to pancreatitis
- (2013) Lars Berglund et al. BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
- Apolipoprotein C-III
- (2013) Murray W. Huff et al. CIRCULATION RESEARCH
- Antisense Oligonucleotide Inhibition of Apolipoprotein C-III Reduces Plasma Triglycerides in Rodents, Nonhuman Primates, and Humans
- (2013) Mark J. Graham et al. CIRCULATION RESEARCH
- Molecular analysis of chylomicronemia in a clinical laboratory setting: Diagnosis of 13 cases of lipoprotein lipase deficiency
- (2013) Jesús M. Martín-Campos et al. CLINICA CHIMICA ACTA
- Plasmapheresis in the Management of Severe Hypertriglyceridemia
- (2013) G. Seda et al. Critical Care Nurse
- Diacylglycerol acyltransferase 1 inhibition with AZD7687 alters lipid handling and hormone secretion in the gut with intolerable side effects: a randomized clinical trial
- (2013) H. Denison et al. DIABETES OBESITY & METABOLISM
- Liver as a target for oligonucleotide therapeutics
- (2013) Alfica Sehgal et al. JOURNAL OF HEPATOLOGY
- Diacylglycerol acyltransferase-1 inhibition enhances intestinal fatty acid oxidation and reduces energy intake in rats
- (2013) Gudrun Schober et al. JOURNAL OF LIPID RESEARCH
- Current Status of the Research and Development of Diacylglycerol O-Acyltransferase 1 (DGAT1) Inhibitors
- (2013) Robert J. DeVita et al. JOURNAL OF MEDICINAL CHEMISTRY
- Pharmacotherapies for lipid modification: beyond the statins
- (2013) Antonio M. Gotto et al. Nature Reviews Cardiology
- Hypertriglyceridemia
- (2013) Amanda Brahm et al. Nutrients
- Severe Hypertriglyceridemia With Pancreatitis
- (2013) Frank M. Sacks et al. JAMA Internal Medicine
- Medical resource use and costs associated with chylomicronemia
- (2013) Daniel Gaudet et al. JOURNAL OF MEDICAL ECONOMICS
- The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management
- (2013) Robert A Hegele et al. Lancet Diabetes & Endocrinology
- Transient Infantile Hypertriglyceridemia, Fatty Liver, and Hepatic Fibrosis Caused by Mutated GPD1, Encoding Glycerol-3-Phosphate Dehydrogenase 1
- (2012) Lina Basel-Vanagaite et al. AMERICAN JOURNAL OF HUMAN GENETICS
- The Complex Genetic Basis of Plasma Triglycerides
- (2012) Christopher T. Johansen et al. Current Atherosclerosis Reports
- Gene therapy for lipoprotein lipase deficiency
- (2012) Daniel Gaudet et al. CURRENT OPINION IN LIPIDOLOGY
- Proof of mechanism for the DGAT1 inhibitor AZD7687: results from a first-time-in-human single-dose study
- (2012) H. Denison et al. DIABETES OBESITY & METABOLISM
- Alipogene tiparvovec: gene therapy for lipoprotein lipase deficiency
- (2012) Anthony S Wierzbicki et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Efficacy and long-term safety of alipogene tiparvovec (AAV1-LPLS447X) gene therapy for lipoprotein lipase deficiency: an open-label trial
- (2012) D Gaudet et al. GENE THERAPY
- Chylomicronemia mutations yield new insights into interactions between lipoprotein lipase and GPIHBP1
- (2012) Peter Gin et al. HUMAN MOLECULAR GENETICS
- New lipid-lowering drugs: an update
- (2012) A. S. Wierzbicki et al. INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
- Effect of Alipogene Tiparvovec (AAV1-LPLS447X) on Postprandial Chylomicron Metabolism in Lipoprotein Lipase-Deficient Patients
- (2012) André C. Carpentier et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- The DGAT1 Inhibitor LCQ908 Decreases Triglyceride Levels in Patients with the Familial Chylomicronemia Syndrome
- (2012) Charles Meyers et al. Journal of Clinical Lipidology
- Clinical and economic benefits observed when follow-up triglyceride levels are less than 500 mg/dL in patients with severe hypertriglyceridemia
- (2012) Jennifer B. Christian et al. Journal of Clinical Lipidology
- Treatment options for the management of hypertriglyceridemia: Strategies based on the best-available evidence
- (2012) Kevin C. Maki et al. Journal of Clinical Lipidology
- Antisense inhibition of apoB synthesis with mipomersen reduces plasma apoC-III and apoC-III-containing lipoproteins
- (2012) Jeremy D. Furtado et al. JOURNAL OF LIPID RESEARCH
- Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study
- (2012) Marina Cuchel et al. LANCET
- The chronic effects of fish oil with exercise on postprandial lipaemia and chylomicron homeostasis in insulin resistant viscerally obese men
- (2012) Karin M Slivkoff-Clark et al. Nutrition & Metabolism
- Triglycerides and Heart Disease
- (2011) Ira J. Goldberg et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- An Increased Burden of Common and Rare Lipid-Associated Risk Alleles Contributes to the Phenotypic Spectrum of Hypertriglyceridemia
- (2011) Christopher T. Johansen et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Apolipoprotein A-V; a potent triglyceride reducer
- (2011) Stefan K. Nilsson et al. ATHEROSCLEROSIS
- Lipase maturation factor 1: A lipase chaperone involved in lipid metabolism
- (2011) Miklós Péterfy BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Regulation of triglyceride metabolism by Angiopoietin-like proteins
- (2011) Frits Mattijssen et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Allelic and phenotypic spectrum of plasma triglycerides
- (2011) Christopher T. Johansen et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Excess of Rare Variants in Non–Genome-Wide Association Study Candidate Genes in Patients With Hypertriglyceridemia
- (2011) Christopher T. Johansen et al. Circulation-Cardiovascular Genetics
- Genetic bases of hypertriglyceridemic phenotypes
- (2011) Christopher T. Johansen et al. CURRENT OPINION IN LIPIDOLOGY
- Diagnosis and Management of Type I and Type V Hyperlipoproteinemia
- (2011) Takanari Gotoda et al. Journal of Atherosclerosis and Thrombosis
- Targeting Acyl-CoA:Diacylglycerol Acyltransferase 1 (DGAT1) with Small Molecule Inhibitors for the Treatment of Metabolic Diseases
- (2011) Jingsong Cao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Deletion of GPIHBP1 causing severe chylomicronemia
- (2011) Jonathan J. Rios et al. JOURNAL OF INHERITED METABOLIC DISEASE
- GPIHBP1, an endothelial cell transporter for lipoprotein lipase
- (2011) Stephen G. Young et al. JOURNAL OF LIPID RESEARCH
- Incidence of pancreatitis, secondary causes, and treatment of patients referred to a specialty lipid clinic with severe hypertriglyceridemia: a retrospective cohort study
- (2011) Supna Sandhu et al. Lipids in Health and Disease
- Mutations in lipoprotein lipase that block binding to the endothelial cell transporter GPIHBP1
- (2011) C. V. Voss et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- GPIHBP1 and the processing of triglyceride-rich lipoproteins
- (2010) Anne P Beigneux Clinical Lipidology
- Management of Hypertriglyceridemia in the Diabetic Patient
- (2010) Ishwarlal Jialal et al. Current Diabetes Reports
- Plasmapheresis in the treatment of hypertriglyceridemia-induced pancreatitis: A community hospital's experience
- (2010) H. Syed et al. JOURNAL OF CLINICAL APHERESIS
- Genetic determinants of plasma triglycerides
- (2010) Christopher T. Johansen et al. JOURNAL OF LIPID RESEARCH
- Biological, clinical and population relevance of 95 loci for blood lipids
- (2010) Tanya M. Teslovich et al. NATURE
- Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia
- (2010) Christopher T Johansen et al. NATURE GENETICS
- Chylomicronemia With a Mutant GPIHBP1 (Q115P) That Cannot Bind Lipoprotein Lipase
- (2009) Anne P. Beigneux et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- A novel APOA5 splicing mutation IVS2+1g>a in a Japanese chylomicronemia patient
- (2009) Minoru Okubo et al. ATHEROSCLEROSIS
- Severe Hypertriglyceridemia: An indication for apheresis?
- (2009) Nils Ewald et al. ATHEROSCLEROSIS SUPPLEMENTS
- Novel LPL mutations associated with lipoprotein lipase deficiency: two case reports and a literature review
- (2009) Amit R. Rahalkar et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- Effects of ezetimibe and simvastatin on apolipoprotein B metabolism in males with mixed hyperlipidemia
- (2009) André J Tremblay et al. JOURNAL OF LIPID RESEARCH
- Mutation of conserved cysteines in the Ly6 domain of GPIHBP1 in familial chylomicronemia
- (2009) Gunilla Olivecrona et al. JOURNAL OF LIPID RESEARCH
- Hypertriglyceridemia: phenomics and genomics
- (2009) Robert A. Hegele et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Plasma lipoproteins: genetic influences and clinical implications
- (2009) Robert A. Hegele NATURE REVIEWS GENETICS
- Mechanism of Action of Niacin
- (2008) Vaijinath S. Kamanna et al. AMERICAN JOURNAL OF CARDIOLOGY
- Chylomicronemia and the Chylomicronemia Syndrome: A Practical Approach to Management
- (2008) David Alexander Leaf AMERICAN JOURNAL OF MEDICINE
- Omega-3 fatty acid concentrates in the treatment of moderate hypertriglyceridemia
- (2008) Ann C Skulas-Ray et al. EXPERT OPINION ON PHARMACOTHERAPY
- GPIHBP1, a GPI-anchored protein required for the lipolytic processing of triglyceride-rich lipoproteins
- (2008) Anne P. Beigneux et al. JOURNAL OF LIPID RESEARCH
- Monogenic pediatric dyslipidemias: Classification, genetics and clinical spectrum
- (2007) Amit R. Rahalkar et al. MOLECULAR GENETICS AND METABOLISM
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