Article
Endocrinology & Metabolism
Xuelan Li, Pingping Guo, Christophe Blockeel, Xinning Li, Ling Deng, Jie Yang, Chujun Li, Min Lin, Haocun Wu, Guifeng Cai, Yunzhao Hu, Xin Chen
Summary: This study aimed to investigate the effect of storage duration of vitrified warmed embryos on pregnancy and neonatal outcomes. The results showed that within a storage period of up to 7 years, there was no impact on the pregnancy and neonatal outcomes of embryos after vitrification.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Endocrinology & Metabolism
Lin Song, Zhiqin Bu, Yingpu Sun
Summary: This study aimed to investigate the relationship between endometrial thickness and early pregnancy complications in frozen thawed embryo transfer cycles. The results showed that thin endometrium was associated with an increased risk of ectopic pregnancy and early spontaneous miscarriage. Therefore, endometrial thickness can serve as an independent predictor for early pregnancy complications.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Medicine, General & Internal
Wenjing Zhou, Zhaojun Cheng, Chong Wang, Ying Feng
Summary: Sequential transplantation is a new mode of in vitro fertilization and embryo transfer. This study compared the clinical outcomes of sequential transplantation, embryo transplantation, and blastocyst transplantation in freeze-thaw embryo transfer cycles. The results showed that the sequential transplantation group had a significantly higher number of transplanted embryos than the other two groups, and the blastocyst transplantation group had the highest implantation rate. The sequential transplantation cycle can achieve a higher clinical pregnancy rate and minimize wastage of transplanted embryos, making it a viable choice for some patients in resuscitation transplantation cycles.
Article
Obstetrics & Gynecology
Adva Aizer, Meirav Noach-Hirsh, Olga Dratviman-Storobinsky, Ravit Nahum, Ronit Machtinger, Yuval Yung, Jigal Haas, Raoul Orvieto
Summary: This study examined the effect of COVID-19 infection or vaccination on frozen-thawed embryo transfer (FET), and found that these factors did not affect patients' performance or implantation in subsequent FET cycles.
FERTILITY AND STERILITY
(2022)
Article
Endocrinology & Metabolism
Shengluan Tang, Tong Du, Jialyu Huang, Hongjuan Ye, Ming Zhao, Jiaying Lin, Yanping Kuang
Summary: This study evaluated the pregnancy and neonatal outcomes in women who had undergone wedge resection for interstitial pregnancy during frozen-thawed embryo transfer cycles. The results showed that women with previous wedge resection were at a higher risk of ectopic pregnancy and uterine rupture, but there were no significant differences in clinical pregnancy rate, live birth rate, and neonatal outcomes. The study recommended cesarean section for these patients and further studies are needed to validate the current recommendations.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2022)
Article
Obstetrics & Gynecology
Jiaying Lin, Haiyan Guo, Bian Wang, Qiuju Chen, Qianqian Zhu
Summary: This study found that women with PCOS have higher odds of preterm birth after FET, but lower odds of low birth weight and SGA, especially in the subgroup with normal BMI.
FERTILITY AND STERILITY
(2021)
Article
Medicine, General & Internal
Zhijie Hu, Danjun Li, Qiuju Chen, Weiran Chai, Qifeng Lyu, Renfei Cai, Yanping Kuang, Xuefeng Lu
Summary: In this large-sample retrospective study, the incidence of ectopic pregnancy (EP) in frozen embryo transfer (FET) cycles was found to be slightly lower than fresh embryo transfer (ET) cycles, with no significant difference. Among patients undergoing ET cycles, the long agonist protocol was associated with a significantly lower risk of EP compared to the GnRH antagonist protocol.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Yi-ran Du, Ke Yang, Jie Liu
Summary: The effects of serum estrogen levels on pregnancy outcomes in hormone replacement cycles were investigated. The study found that the serum estrogen levels before frozen-thawed blastocyst transfer did not affect pregnancy outcomes, and age was found to be an independent factor affecting clinical pregnancy.
SCIENTIFIC REPORTS
(2023)
Article
Obstetrics & Gynecology
M. L. Boutet, G. Casals, B. Valenzuela-Alcaraz, L. Garcia-Otero, F. Crovetto, M. S. Civico, A. Borras, D. Manau, E. Gratacos, F. Crispi
Summary: The study found that embryos transfer impacts fetal cardiac remodeling and suboptimal function, with more pronounced changes after fresh embryo transfer compared to frozen embryo transfer. Fetuses conceived by assisted reproductive technologies showed larger atria, more globular ventricles, and thicker myocardial walls, as well as signs of suboptimal systolic and diastolic function as compared to spontaneously conceived pregnancies.
HUMAN REPRODUCTION
(2021)
Article
Medicine, General & Internal
Yao Chen, Jianbo Zhou, Yandong Chen, Jihong Yang, Yingying Hao, Ting Feng, Ruizhi Feng, Yun Qian
Summary: Among women of advanced maternal age, there was no significant difference in live birth rates between frozen embryo transfer and fresh embryo transfer. However, frozen embryo transfer resulted in higher birthweights and a lower incidence of preterm births.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Obstetrics & Gynecology
Linette van Duijn, Melek Rousian, Igna F. Reijnders, Sten P. Willemsen, Esther B. Baart, Joop S. E. Laven, Regine P. M. Steegers-Theunissen
Summary: The study found that the method of embryo transfer did not significantly impact early placental development, but frozen-thawed embryo transfer had a beneficial impact on uterine artery Doppler indices in the second and third trimesters.
HUMAN REPRODUCTION
(2021)
Article
Medicine, General & Internal
Hongcheng He, Dan Qi, Mei Fang, Yizheng Tian, Lei Yan, Jinlong Ma, Yanbo Du
Summary: Low-dose aspirin is commonly used in frozen-embryo transfer (FET) cycles, but the effect of short-term aspirin administration on pregnancy outcomes is unclear. In this retrospective study, we analyzed the outcomes and complications of 4454 programmed FET cycles and found that the short-term use of aspirin did not improve live birth rates or reduce the incidence of pregnancy complications. Based on our findings, short-term administration of low-dose aspirin may not benefit young women undergoing frozen-thawed embryo transfer cycles.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Yaping Jiang, Rui Jiang, Hui He, Xinling Ren, Qiong Yu, Lei Jin
Summary: Embryo development speed and morphology score are important factors in frozen-thawed embryo transfer (FET) outcomes. D5 embryos are generally preferred over D6 embryos, but there is some variation in clinical outcomes. This study found that AA/AB blastocysts showed similar pregnancy outcomes regardless of development day, while BA/BB/BC blastocysts had better outcomes on D5 than D6. Comparing BC embryos on D5 and BA/BB embryos on D6, no differences were observed in clinical pregnancy outcomes and neonatal outcomes, but D6 BA/BB embryos had a higher miscarriage rate, which was not statistically significant after adjusting for confounding factors.
BMC PREGNANCY AND CHILDBIRTH
(2023)
Article
Cell Biology
Li Fan, Ni Tang, Chunling Yao, Xiaohua Wei, Yongmei Tang, Jingjing Li, Wenjie Huang
Summary: Frozen-thawed embryo transfers (FETs) are more likely to result in live births and clinical pregnancies compared to fresh embryo transfers in cycles employing the GnRH antagonist protocol.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Andrology
Pengcheng Kong, Yanan Liu, Qianqian Zhu, Mingru Yin, Xiaoming Teng
Summary: The study concluded that male age did not have an impact on pregnancy or neonatal outcomes in infertile couples undergoing their first frozen-thawed embryo transfer cycles when the female partner was under 36 years old.
Article
Obstetrics & Gynecology
Nasim Tabibnejad, Mohammad Hasan Sheikhha, Nasrin Ghasemi, Farzaneh Fesahat, Mehrdad Soleimani, Abbas Aflatoonian
REPRODUCTIVE BIOMEDICINE ONLINE
(2019)
Article
Obstetrics & Gynecology
Abbas Aflatoonian, Marzieh Lotfi, Lida Saeed, Nasim Tabibnejad
Summary: This study found that 47% of women with poor ovarian response had spontaneous pregnancy after PRP injection, while 22.2% of women with POI restored menstruation after the second injection. However, there were no significant differences in hormone levels and subsequent pregnancy outcomes.
REPRODUCTIVE SCIENCES
(2021)
Article
Endocrinology & Metabolism
Fereshteh Esfandiari, Fereshteh Chitsazian, Masoumeh Golestan Jahromi, Raha Favaedi, Masood Bazrgar, Reza Aflatoonian, Parvaneh Afsharian, Abbas Aflatoonian, Maryam Shahhoseini
Summary: Endometriosis is a major gynecological disease with unknown cause and no definite cure. Research shows that HOX genes play critical roles in pathophysiology of endometriosis and may assist with disease diagnosis and treatment.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
(2021)
Article
Obstetrics & Gynecology
Abbas Aflatoonian, Zohreh Pezeshkpour, Yasamin Mehrolhasani, Nasim Tabibnejhad
Summary: The study revealed that misoprostol can remove up to 40% of endometrial polyps. This drug has the potential to be used as a safe and low-cost first-line treatment.
INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE
(2022)
Article
Obstetrics & Gynecology
Abbas Aflatoonian, Banafsheh Mohammadi
Summary: This study compared the safety and efficacy of low-dose subcutaneous progesterone with vaginal progesterone for luteal-phase support in frozen-thawed embryo transfer patients. The results showed a slightly higher pregnancy rate with vaginal progesterone, but the difference was not statistically significant.
INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE
(2021)
Article
Obstetrics & Gynecology
Abbas Aflatoonian, Nasim Tabibnejad
INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE
(2020)
Article
Obstetrics & Gynecology
Abbas Aflatoonian, Fatemeh Haghighi, Masrooreh Hoseini, Saeid Haghdani
INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE
(2020)
Article
Obstetrics & Gynecology
Farahnaz Farnia, Abbas Aflatoonian, Athareh Kalantari
INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE
(2019)
Meeting Abstract
Obstetrics & Gynecology
Z. Zandieh, A. Gavahi, F. Asgari, F. Amjadi, V. Akram, L. Bajelan, A. Aflatoonian, R. Aflatoonian
HUMAN REPRODUCTION
(2019)
Meeting Abstract
Obstetrics & Gynecology
F. Chitsazian, R. Favaedi, M. Golestan Jahromi, M. Bazrgar, R. Aflatoonian, A. Aflatoonian, P. Afsharian, M. Shahhoseini
HUMAN REPRODUCTION
(2019)
Article
Obstetrics & Gynecology
Saeedeh Dashti, Abbas Aflatoonian, Nasim Tabibnejad
INTERNATIONAL JOURNAL OF FERTILITY & STERILITY
(2019)
Article
Obstetrics & Gynecology
Masoumeh Golestan Jahromi, Reza Aflatoonian, Parvaneh Afsharian, Samaneh Aghajanpour, Maryam Shahhoseini, Abbas Aflatoonian
INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE
(2018)
Article
Obstetrics & Gynecology
Azam Babaki, Ehsan Zare Mehrjardi, Razieh Dehghani Firouzabadi, Abbas Aflatoonian, Seyed Morteza Seifati
INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE
(2018)
Article
Obstetrics & Gynecology
Nasim Tabibnejad, Mehrdad Soleimani, Abbas Aflatoonian
INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE
(2018)
Article
Obstetrics & Gynecology
Fatemehsadat Amjadi, Zahra Zandieh, Ensieh Salehi, Reza Jafari, Nasrin Ghasemi, Abbas Aflatoonian, Alireza Fazeli, Reza Aflatoonian
CLINICAL AND EXPERIMENTAL REPRODUCTIVE MEDICINE-CERM
(2018)