标题
New medical therapies for heart failure
作者
关键词
-
出版物
Nature Reviews Cardiology
Volume 12, Issue 12, Pages 730-740
出版商
Springer Nature
发表日期
2015-09-29
DOI
10.1038/nrcardio.2015.137
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Meta-Analysis of Large-Scale Randomized Trials to Determine the Effectiveness of Inhibition of the Renin-Angiotensin Aldosterone System in Heart Failure
- (2015) Connor A. Emdin et al. AMERICAN JOURNAL OF CARDIOLOGY
- Rationale and design of MinerAlocorticoid Receptor antagonist Tolerability Study-Heart Failure (ARTS-HF): a randomized study of finerenone vs. eplerenone in patients who have worsening chronic heart failure with diabetes and/or chronic kidney disease
- (2015) Bertram Pitt et al. EUROPEAN JOURNAL OF HEART FAILURE
- Renal effects of the angiotensin receptor neprilysin inhibitor LCZ696 in patients with heart failure and preserved ejection fraction
- (2015) Adriaan A. Voors et al. EUROPEAN JOURNAL OF HEART FAILURE
- Combined angiotensin receptor blockade and neprilysin inhibition attenuates angiotensin-II mediated renal cellular collagen synthesis
- (2015) Bing H. Wang et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Neprilysin inhibitors preserve renal function in heart failure
- (2015) Fiona Bodey et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- The vulnerable phase after hospitalization for heart failure
- (2015) Stephen J. Greene et al. Nature Reviews Cardiology
- Safety and Tolerability of Omecamtiv Mecarbil During Exercise in Patients With Ischemic Cardiomyopathy and Angina
- (2015) Barry H. Greenberg et al. JACC-Heart Failure
- Outcomes in patients with heart failure with preserved, borderline, and reduced ejection fraction in the Medicare population
- (2014) Richard K. Cheng et al. AMERICAN HEART JOURNAL
- Soluble guanylyl cyclase activation improves progressive cardiac remodeling and failure after myocardial infarction. Cardioprotection over ACE inhibition
- (2014) Daniela Fraccarollo et al. BASIC RESEARCH IN CARDIOLOGY
- Inhibition of phosphodiesterase-3 by levosimendan is sufficient to account for its inotropic effect in failing human heart
- (2014) Ø Ørstavik et al. BRITISH JOURNAL OF PHARMACOLOGY
- Determinants of Early Readmission After Hospitalization for Heart Failure
- (2014) Cathy A. Eastwood et al. CANADIAN JOURNAL OF CARDIOLOGY
- Left Atrium in Heart Failure With Preserved Ejection Fraction
- (2014) Andrea Rossi et al. Circulation-Heart Failure
- Elevation in High-Sensitivity Troponin T in Heart Failure and Preserved Ejection Fraction and Influence of Treatment With the Angiotensin Receptor Neprilysin Inhibitor LCZ696
- (2014) Pardeep S. Jhund et al. Circulation-Heart Failure
- A putative placebo analysis of the effects of LCZ696 on clinical outcomes in heart failure
- (2014) J. McMurray et al. EUROPEAN HEART JOURNAL
- Worsening renal function during renin-angiotensin-aldosterone system inhibitor initiation and long-term outcomes in patients with left ventricular systolic dysfunction
- (2014) Hannah Clark et al. EUROPEAN JOURNAL OF HEART FAILURE
- Prognosis and response to therapy of first inpatient and outpatient heart failure event in a heart failure clinical trial: MADIT-CRT
- (2014) Hicham Skali et al. EUROPEAN JOURNAL OF HEART FAILURE
- Baseline characteristics and treatment of patients in Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure trial (PARADIGM-HF)
- (2014) John J. V. McMurray et al. EUROPEAN JOURNAL OF HEART FAILURE
- Rationale and design of the SOluble guanylate Cyclase stimulatoR in heArT failurE Studies (SOCRATES)
- (2014) Burkert Pieske et al. EUROPEAN JOURNAL OF HEART FAILURE
- An overview of recent developments in the treatment of heart failure: update from the ESC Congress 2013
- (2014) Miroslava Valentova et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- In-hospital and 1-year outcomes of acute heart failure patients according to presentation (de novo vs. worsening) and ejection fraction. Results from IN-HF Outcome Registry
- (2014) Michele Senni et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Finerenone, a Novel Selective Nonsteroidal Mineralocorticoid Receptor Antagonist Protects From Rat Cardiorenal Injury
- (2014) Peter Kolkhof et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Inotropes
- (2014) Gary S. Francis et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure
- (2014) John J.V. McMurray et al. NEW ENGLAND JOURNAL OF MEDICINE
- Current role of neprilysin inhibitors in hypertension and heart failure
- (2014) Thomas G. von Lueder et al. PHARMACOLOGY & THERAPEUTICS
- Anti‐Remodeling and Anti‐Fibrotic Effects of the Neuregulin‐1β Glial Growth Factor 2 in a Large Animal Model of Heart Failure
- (2014) Cristi L. Galindo et al. Journal of the American Heart Association
- Uptitration of Renin-Angiotensin System Blocker and Beta-Blocker Therapy in Patients Hospitalized for Heart Failure With Reduced Versus Preserved Left Ventricular Ejection Fractions
- (2013) Frederik H. Verbrugge et al. AMERICAN JOURNAL OF CARDIOLOGY
- Riociguat for Patients With Pulmonary Hypertension Caused by Systolic Left Ventricular Dysfunction
- (2013) Diana Bonderman et al. CIRCULATION
- Heart Disease and Stroke Statistics—2014 Update
- (2013) Alan S. Go et al. CIRCULATION
- Renin–Angiotensin Blockade Combined With Natriuretic Peptide System Augmentation
- (2013) Thomas G. von Lueder et al. Circulation-Heart Failure
- Incidence, Determinants, and Prognostic Significance of Hyperkalemia and Worsening Renal Function in Patients With Heart Failure Receiving the Mineralocorticoid Receptor Antagonist Eplerenone or Placebo in Addition to Optimal Medical Therapy
- (2013) Patrick Rossignol et al. Circulation-Heart Failure
- Diuretic Use in Heart Failure and Outcomes
- (2013) T G von Lueder et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Effect of aliskiren on post-discharge outcomes among diabetic and non-diabetic patients hospitalized for heart failure: insights from the ASTRONAUT trial
- (2013) A. P. Maggioni et al. EUROPEAN HEART JOURNAL
- Serelaxin in acute heart failure patients with preserved left ventricular ejection fraction: results from the RELAX-AHF trial
- (2013) G. Filippatos et al. EUROPEAN HEART JOURNAL
- A randomized, double-blind, placebo-controlled, multicentre study to assess haemodynamic effects of serelaxin in patients with acute heart failure
- (2013) Piotr Ponikowski et al. EUROPEAN HEART JOURNAL
- Safety and tolerability of the novel non-steroidal mineralocorticoid receptor antagonist BAY 94-8862 in patients with chronic heart failure and mild or moderate chronic kidney disease: a randomized, double-blind trial
- (2013) Bertram Pitt et al. EUROPEAN HEART JOURNAL
- Dual angiotensin receptor and neprilysin inhibition as an alternative to angiotensin-converting enzyme inhibition in patients with chronic systolic heart failure: rationale for and design of the Prospective comparison of ARNI with ACEI to Determine Impact
- (2013) John J. V. McMurray et al. EUROPEAN JOURNAL OF HEART FAILURE
- Losing ALTITUDE? How should ASTRONAUT launch into ATMOSPHERE
- (2013) Henry Krum et al. EUROPEAN JOURNAL OF HEART FAILURE
- Effect of Aliskiren on Postdischarge Mortality and Heart Failure Readmissions Among Patients Hospitalized for Heart Failure
- (2013) Mihai Gheorghiade et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- BLOOD HYPEROSMOLARITY AS A PREDICTOR OF MORTALITY IN PATIENTS AFTER ACUTE CORONARY SYNDROME: HOW DEHYDRATION AFFECTS THE PROGNOSIS OF OUR PATIENTS
- (2013) Sem Briongos-Figuero et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Targeting the renin–angiotensin–aldosterone system in heart failure
- (2013) Chim C. Lang et al. Nature Reviews Cardiology
- Riociguat for the Treatment of Chronic Thromboembolic Pulmonary Hypertension
- (2013) Hossein-Ardeschir Ghofrani et al. NEW ENGLAND JOURNAL OF MEDICINE
- Intravenous Glial Growth Factor 2 (GGF2) Isoform of Neuregulin-1β Improves Left Ventricular Function, Gene and Protein Expression in Rats after Myocardial Infarction
- (2013) Michael F. Hill et al. PLoS One
- RAAS Inhibitors and Cardiovascular Protection in Large Scale Trials
- (2012) Thomas G. von Lueder et al. CARDIOVASCULAR DRUGS AND THERAPY
- Discovery of BAY 94-8862: A Nonsteroidal Antagonist of the Mineralocorticoid Receptor for the Treatment of Cardiorenal Diseases
- (2012) Lars Bärfacker et al. ChemMedChem
- Neutral endopeptidase inhibition and the natriuretic peptide system: an evolving strategy in cardiovascular therapeutics
- (2012) Sarah Mangiafico et al. EUROPEAN HEART JOURNAL
- Cinaciguat, a soluble guanylate cyclase activator, unloads the heart but also causes hypotension in acute decompensated heart failure†
- (2012) Erland Erdmann et al. EUROPEAN HEART JOURNAL
- ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association (HFA) of the ESC
- (2012) et al. EUROPEAN HEART JOURNAL
- Cinaciguat, a soluble guanylate cyclase activator: results from the randomized, controlled, phase IIb COMPOSE programme in acute heart failure syndromes
- (2012) Mihai Gheorghiade et al. EUROPEAN JOURNAL OF HEART FAILURE
- Aliskiren, ALTITUDE, and the implications for ATMOSPHERE
- (2012) John J.V. McMurray et al. EUROPEAN JOURNAL OF HEART FAILURE
- Soluble guanylate cyclase: a potential therapeutic target for heart failure
- (2012) Mihai Gheorghiade et al. HEART FAILURE REVIEWS
- The angiotensin receptor neprilysin inhibitor LCZ696 in heart failure with preserved ejection fraction: a phase 2 double-blind randomised controlled trial
- (2012) Scott D Solomon et al. LANCET
- Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial
- (2012) John R Teerlink et al. LANCET
- Cardiorenal End Points in a Trial of Aliskiren for Type 2 Diabetes
- (2012) Hans-Henrik Parving et al. NEW ENGLAND JOURNAL OF MEDICINE
- CD-NP: A Novel Engineered Dual Guanylyl Cyclase Activator with Anti-Fibrotic Actions in the Heart
- (2012) Fernando L. Martin et al. PLoS One
- The Soluble Guanylyl Cyclase Activator Bay 58-2667 Selectively Limits Cardiomyocyte Hypertrophy
- (2012) Jennifer C. Irvine et al. PLoS One
- Effect of Aliskiren in Patients with Heart Failure According to Background Dose of ACE Inhibitor: A Retrospective Analysis of the Aliskiren Observation of Heart Failure Treatment (ALOFT) Trial
- (2011) Novalia P. Sidik et al. CARDIOVASCULAR DRUGS AND THERAPY
- Neurohumoral effects of aliskiren in patients with symptomatic heart failure receiving a mineralocorticoid receptor antagonist: the Aliskiren Observation of Heart Failure Treatment study
- (2011) Bertram Pitt et al. EUROPEAN JOURNAL OF HEART FAILURE
- CONSENSUS to EMPHASIS: the overwhelming evidence which makes blockade of the renin-angiotensin-aldosterone system the cornerstone of therapy for systolic heart failure
- (2011) John J.V. McMurray EUROPEAN JOURNAL OF HEART FAILURE
- Clinical presentation, management and outcomes in the Acute Heart Failure Global Survey of Standard Treatment (ALARM-HF)
- (2011) F. Follath et al. INTENSIVE CARE MEDICINE
- Concomitant Angiotensin AT1 Receptor Antagonism and Neprilysin Inhibition Produces Omapatrilat-like Antihypertensive Effects Without Promoting Tracheal Plasma Extravasation in the Rat
- (2011) Laxminarayan G Hegde et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- The effects of the cardiac myosin activator, omecamtiv mecarbil, on cardiac function in systolic heart failure: a double-blind, placebo-controlled, crossover, dose-ranging phase 2 trial
- (2011) John GF Cleland et al. LANCET
- Dose-dependent augmentation of cardiac systolic function with the selective cardiac myosin activator, omecamtiv mecarbil: a first-in-man study
- (2011) John R Teerlink et al. LANCET
- Mineralocorticoid receptors in vascular function and disease
- (2011) Amy McCurley et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Effect of Nesiritide in Patients with Acute Decompensated Heart Failure
- (2011) C.M. O'Connor et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cardiac Myosin Activation: A Potential Therapeutic Approach for Systolic Heart Failure
- (2011) F. I. Malik et al. SCIENCE
- Improvement of Cardiac Function by a Cardiac Myosin Activator in Conscious Dogs With Systolic Heart Failure
- (2010) You-Tang Shen et al. Circulation-Heart Failure
- Renin Inhibitors in Chronic Heart Failure: The Aliskiren Observation of Heart Failure Treatment Study in Context
- (2010) Henry Krum et al. CLINICAL CARDIOLOGY
- Population Pharmacokinetics and Pharmacodynamics of Cinaciguat, a Soluble Guanylate Cyclase Activator, in Patients with Acute Decompensated Heart Failure
- (2010) Wolfgang Mueck et al. CLINICAL PHARMACOKINETICS
- Rationale and design of the multicentre, randomized, double-blind, placebo-controlled Aliskiren Trial on Acute Heart Failure Outcomes (ASTRONAUT)
- (2010) Mihai Gheorghiade et al. EUROPEAN JOURNAL OF HEART FAILURE
- Direct renin inhibition in addition to or as an alternative to angiotensin converting enzyme inhibition in patients with chronic systolic heart failure: rationale and design of the Aliskiren Trial to Minimize OutcomeS in Patients with HEart failuRE (ATMOS
- (2010) Henry Krum et al. EUROPEAN JOURNAL OF HEART FAILURE
- A Phase II, Randomized, Double-Blind, Multicenter, Based on Standard Therapy, Placebo-Controlled Study of the Efficacy and Safety of Recombinant Human Neuregulin-1 in Patients With Chronic Heart Failure
- (2010) Runlin Gao et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Comparison of Dopamine and Norepinephrine in the Treatment of Shock
- (2010) Daniel De Backer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Eplerenone in Patients with Systolic Heart Failure and Mild Symptoms
- (2010) Faiez Zannad et al. NEW ENGLAND JOURNAL OF MEDICINE
- Aldosterone and Mineralocorticoid Receptors in the Cardiovascular System
- (2010) John W. Funder PROGRESS IN CARDIOVASCULAR DISEASES
- Discovery of Omecamtiv Mecarbil the First, Selective, Small Molecule Activator of Cardiac Myosin
- (2010) Bradley P. Morgan et al. ACS Medicinal Chemistry Letters
- Cinaciguat (BAY 58–2667) Improves Cardiopulmonary Hemodynamics in Patients With Acute Decompensated Heart Failure
- (2009) Harald Lapp et al. CIRCULATION
- Effects of low-dose oral enoximone administration on mortality, morbidity, and exercise capacity in patients with advanced heart failure: the randomized, double-blind, placebo-controlled, parallel group ESSENTIAL trials
- (2009) M. Metra et al. EUROPEAN HEART JOURNAL
- BAY 58-2667, a nitric oxide-independent guanylyl cyclase activator, pharmacologically post-conditions rabbit and rat hearts
- (2009) T. Krieg et al. EUROPEAN HEART JOURNAL
- Use of Aldosterone Antagonists in Heart Failure
- (2009) Nancy M. Albert JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Pharmacodynamics Pharmacodynamics of a Novel Designer Natriuretic Peptide, CD-NP, in a First-in-Human Clinical Trial in Healthy Subjects
- (2009) Candace Y. W. Lee et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Relaxin for the treatment of patients with acute heart failure (Pre-RELAX-AHF): a multicentre, randomised, placebo-controlled, parallel-group, dose-finding phase IIb study
- (2009) John R Teerlink et al. LANCET
- Cardiovascular effects of relaxin: from basic science to clinical therapy
- (2009) Xiao-Jun Du et al. Nature Reviews Cardiology
- Rationale and design of the Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure Trial (ASCEND-HF)
- (2008) Adrian F. Hernandez et al. AMERICAN HEART JOURNAL
- Effects of the Oral Direct Renin Inhibitor Aliskiren in Patients With Symptomatic Heart Failure
- (2008) John J.V. McMurray et al. Circulation-Heart Failure
- Acute heart failure in the emergency department: Short and long-term outcomes of elderly patients with heart failure
- (2008) Justin A. Ezekowitz et al. EUROPEAN JOURNAL OF HEART FAILURE
- Novel Bifunctional Natriuretic Peptides as Potential Therapeutics
- (2008) Deborah M. Dickey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Design, Synthesis, and Actions of a Novel Chimeric Natriuretic Peptide: CD-NP
- (2008) Ondrej Lisy et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Role of renin in heart failure and therapeutic potential of direct renin inhibition
- (2008) Henry Krum JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM
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