Neutral endopeptidase inhibition and the natriuretic peptide system: an evolving strategy in cardiovascular therapeutics

Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes

(2012) Marica Bordicchia et al.   JOURNAL OF CLINICAL INVESTIGATION

INITIAL EXPERIENCE WITH SUBCUTANEOUS INFUSION OF CENDERITIDE IN PATIENTS WITH CHRONIC HEART FAILURE

(2012) Joel Neutel et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Sustained Blood Pressure–Lowering Actions of Subcutaneous B-Type Natriuretic Peptide (Nesiritide) in a Patient With Uncontrolled Hypertension

(2012) Alessandro Cataliotti et al.   MAYO CLINIC PROCEEDINGS

Long-Term Cardiac pro-B-Type Natriuretic Peptide Gene Delivery Prevents the Development of Hypertensive Heart Disease in Spontaneously Hypertensive Rats

(2011) Alessandro Cataliotti et al.   CIRCULATION

Hypertension and Heart Failure

(2011) Richard J. Rodeheffer   CIRCULATION

Long-Term Follow-Up of Participants With Heart Failure in the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)

(2011) Linda B. Piller et al.   CIRCULATION

Comparison of Mass Spectrometry and Clinical Assay Measurements of Circulating Fragments of B-Type Natriuretic Peptide in Patients With Chronic Heart Failure

(2011) Wayne L. Miller et al.   Circulation-Heart Failure

Secretion of Glycosylated Pro-B-Type Natriuretic Peptide from Normal Cardiomyocytes

(2011) J. M. Tonne et al.   CLINICAL CHEMISTRY

Natriuretic peptide metabolism, clearance and degradation

(2011) Lincoln R. Potter   FEBS Journal

A functional XPNPEP2 promoter haplotype leads to reduced plasma aminopeptidase P and increased risk of ACE inhibitor-induced angioedema

(2011) Amy L. Cilia La Corte et al.   HUMAN MUTATION

Low Plasma Level of Atrial Natriuretic Peptide Predicts Development of Diabetes: The Prospective Malmö Diet and Cancer Study

(2011) Martin Magnusson et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Dendroaspis natriuretic peptide and the designer natriuretic peptide, CD-NP, are resistant to proteolytic inactivation

(2011) Deborah M. Dickey et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Pro–B-Type Natriuretic Peptide1–108 Circulates in the General Community

(2011) Fima Macheret et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A Genetic Variant of the Atrial Natriuretic Peptide Gene Is Associated With Cardiometabolic Protection in the General Community

(2011) Valentina Cannone et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

(2011) Georg B. Ehret et al.   NATURE

Effect of Nesiritide in Patients with Acute Decompensated Heart Failure

(2011) C.M. O'Connor et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human B-type natriuretic peptide is not degraded by meprin A

(2010) Deborah M. Dickey et al.   BIOCHEMICAL PHARMACOLOGY

Corin Is Present in the Normal Human Heart, Kidney, and Blood, with Pro-B-Type Natriuretic Peptide Processing in the Circulation

(2010) T. Ichiki et al.   CLINICAL CHEMISTRY

Neprilysin, obesity and the metabolic syndrome

(2010) K F Standeven et al.   INTERNATIONAL JOURNAL OF OBESITY

Blood-pressure reduction with LCZ696, a novel dual-acting inhibitor of the angiotensin II receptor and neprilysin: a randomised, double-blind, placebo-controlled, active comparator study

(2010) Luis Miguel Ruilope et al.   LANCET

Natriuretic Peptides/cGMP/cGMP-Dependent Protein Kinase Cascades Promote Muscle Mitochondrial Biogenesis and Prevent Obesity

(2009) Kazutoshi Miyashita et al.   DIABETES

The T-381C SNP in BNP gene may be modestly associated with type 2 diabetes: an updated meta-analysis in 49 279 subjects

(2009) Hélène Choquet et al.   HUMAN MOLECULAR GENETICS

Next generation multifunctional angiotensin receptor blockers

(2009) Theodore W Kurtz et al.   HYPERTENSION RESEARCH

Pharmacodynamics Pharmacodynamics of a Novel Designer Natriuretic Peptide, CD-NP, in a First-in-Human Clinical Trial in Healthy Subjects

(2009) Candace Y. W. Lee et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Pharmacokinetics and Pharmacodynamics of LCZ696, a Novel Dual-Acting Angiotensin Receptor-Neprilysin Inhibitor (ARNi)

(2009) Jessie Gu et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Natriuretic Peptides Enhance the Production of Adiponectin in Human Adipocytes and in Patients With Chronic Heart Failure

(2009) Osamu Tsukamoto et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Association of common variants in NPPA and NPPB with circulating natriuretic peptides and blood pressure

(2009) Christopher Newton-Cheh et al.   NATURE GENETICS

cGMP rescues mitochondrial dysfunction induced by glucose and insulin in myocytes

(2008) Masanori Mitsuishi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Chronic Actions of a Novel Oral B-Type Natriuretic Peptide Conjugate in Normal Dogs and Acute Actions in Angiotensin II–Mediated Hypertension

(2008) Alessandro Cataliotti et al.   CIRCULATION

Detection of Endogenous B-Type Natriuretic Peptide at Very Low Concentrations in Patients With Heart Failure

(2008) Eric E. Niederkofler et al.   Circulation-Heart Failure

Atrial Natriuretic Peptide Induces Postprandial Lipid Oxidation in Humans

(2008) A. L. Birkenfeld et al.   DIABETES

B-Type Natriuretic Peptide Decreases Gastric Emptying and Absorption

(2008) Anteneh Addisu et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Design, Synthesis, and Actions of a Novel Chimeric Natriuretic Peptide: CD-NP

(2008) Ondrej Lisy et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Effect of bradykinin metabolism inhibitors on evoked hypotension in rats: rank efficacy of enzymes associated with bradykinin-mediated angioedema

(2007) R M Fryer et al.   BRITISH JOURNAL OF PHARMACOLOGY