Article
Agricultural Engineering
Jinpeng Wang, Xiao Yu, Kaifeng Wang, Lu Lin, Hu-Hu Liu, Rodrigo Ledesma-Amaro, Xiao-Jun Ji
Summary: This study explored the optimal biosynthetic pathways for customized production of co6-PUFAs in Y. lipolytica and effectively increased the proportions of co6-PUFAs in total fatty acids through various strategies. The customized strains synthesized GLA, DGLA, and ARA with high titers, providing valuable insights into the production of functional co6-PUFAs.
BIORESOURCE TECHNOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Chaiwat Arjin, Chanmany Souphannavong, Rakkiat Norkeaw, Niraporn Chaiwang, Supamit Mekchay, Apinya Sartsook, Maninphan Thongkham, Thanchanok Yosen, Warintorn Ruksiriwanich, Sarana Rose Sommano, Korawan Sringarm
Summary: The supplementation of perilla cake improved pig performance, increased PUFA fatty acids, and decreased the proportion of saturated and unsaturated fatty acids in pork, while not affecting carcass traits and meat quality. This alternative source of raw material can be considered for functional feed additives in livestock production.
Article
Nutrition & Dietetics
Qingqing Li, Yao Huang, Xingqian Zhang, Cuiyun Zou, Li Lin
Summary: This research examines the impact of different ratios of faba bean on the muscle quality, histological analysis, proximate, amino acids, and fatty acids composition in tilapia. The findings suggest that feeding tilapia with faba beans can improve muscle texture, muscle fibers, amino acids content, and fatty acids content.
FRONTIERS IN NUTRITION
(2023)
Article
Environmental Sciences
Afroza Parvin, Md Kamal Hossain, Umme Fatema Shahjadee, Sharmin Akter Lisa, Mohammad Nashir Uddin, Md Aftab Ali Shaikh, Afsana Parvin, Mohammad Moniruzzaman, Badhan Saha, Priyanka Dey Suchi
Summary: Using tilapia as a model, this study assessed the exposure and risk assessment of trace metals on human health. The nutrient composition of fish muscle, including amino acids, fatty acids, and minerals, was also examined. The results showed that tilapia contained significant concentrations of amino acids, fatty acids, and minerals, making it a good source of protein, fat, and minerals. Hazardous heavy metals were found to be below the maximum tolerable limits. Health-related indices and carcinogenic risk indices were calculated to evaluate the human health hazards, and the results indicated that the consumption of tilapia posed a non-carcinogenic threat to human health. The study also identified the sources of metal contamination and their associations through statistical analyses.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Review
Plant Sciences
James G. Wallis, Jesse D. Bengtsson, John Browse
Summary: Vegetable oils are a major source of calories in human diets but their fatty acid compositions are not ideal. Strategies such as transgenic expression of desaturases and downregulation of FatB thioesterase have been developed to lower oil saturates and improve nutrition.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Maryam Yahay, Zahra Heidari, Zahra Allameh, Reza Amani
Summary: This study found that, compared to olive and sunflower oils, consuming canola oil significantly improved the lipid profile, liver function, and HOMA-IR in women with PCOS.
LIPIDS IN HEALTH AND DISEASE
(2021)
Article
Geriatrics & Gerontology
Varinderpal S. Dhillon, Permal Deo, Ann Chua, Phil Thomas, Michael Fenech
Summary: The study investigated the relationship between red blood cell fatty acid status and lymphocyte telomere length (LTL) in 174 healthy older South Australians. Results showed that saturated and monounsaturated fatty acids were negatively associated with LTL, while polyunsaturated fatty acids, particularly arachidonic acid (C20:4n-6), were positively correlated with LTL. Further research is warranted into the significant association of fatty acids, especially C20:4n-6, with telomere length.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2021)
Article
Food Science & Technology
Zoltan Szabo, Tamas Marosvoelgyi, Eva Szabo, Viktor Koczka, Zsofia Verzar, Maria Figler, Tamas Decsi
Summary: Short-term heating of edible oils leads to changes in fatty acid composition and health-related indices. Regardless of the oil type, heating reduces the levels of linoleic acid and alpha-linolenic acid, while increasing trans fatty acid levels. The oils also show higher atherogenicity and thrombogenicity after heating.
Article
Nutrition & Dietetics
Xuanyi Meng, Yong Wu, Xuefang Wen, Jinyan Gao, Yanhai Xie, Xiaoli Zhao, Jin Yuan, Hao Yang, Zheling Zeng, Xin Li, Hongbing Chen
Summary: This study investigates the influence of polyunsaturated fatty acids (PUFAs) on sensitizing and triggering allergic reactions in mice. The results demonstrate that PUFAs, specifically alpha-linolenic acid (ALA), can induce cross-linking and conformational changes in alpha-lactalbumin (BLA) and beta-lactoglobulin (BLG), promoting allergic reactions in BALB/c mice by disrupting the Th1/Th2 balance and enhancing Th2 immune response.
Article
Nutrition & Dietetics
Hao Chen, Xuebing Leng, Shaohui Liu, Ziqi Zeng, Feng Huang, Rongjie Huang, Yunfeng Zou, Yunan Xu
Summary: This study found that dietary intake of omega-3 polyunsaturated fatty acids (N3-PUFA), particularly alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosapentaenoic acid (DPA), was associated with lower risk of all-cause and cardiovascular mortality among hypertensive adults in the U.S.
CLINICAL NUTRITION
(2023)
Article
Food Science & Technology
Zhiyuan Liu, Jihong Yuan, Ping Wen, Xiaofei Guo, Kelei Li, Yinpeng Wang, Ruirui Liu, Yanjun Guo, Duo Li
Summary: This study aimed to assess the effects of blend oil on liver function markers in healthy subjects. The results showed that blend oil was more effective in reducing liver function markers such as aspartate aminotransferase (AST) and alanine aminotransferase (ALT) compared with soybean oil or lard alone. This suggests that blend oil may be beneficial for preventing non-alcoholic fatty liver disease in the healthy population.
Article
Food Science & Technology
Katja Lehnert, Mamun M. Rashid, Benoy Kumar Barman, Walter Vetter
Summary: Nile tilapia in Bangladesh were grown using four different feeding treatments for a project aimed at cost-effectively producing fish for low-income consumers in developing countries. Analysis revealed a variety of fatty acids in fillet and head tissue, with palmitic acid and oleic acid being the major ones, while fillet contained higher proportions of linoleic acid and polyunsaturated fatty acids. Additionally, a rare dicarboxylic fatty acid, azelaic acid (Di9:0), was found in head tissue.
EUROPEAN FOOD RESEARCH AND TECHNOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Priyanshu Jain, Amritpreet Kaur Minhas, Sadhana Shukla, Munish Puri, Colin J. Barrow, Shovon Mandal
Summary: This study isolated several indigenous microalgal strains from the Arabian Sea coast and identified two strains with high production of polyunsaturated fatty acids (PUFAs). The strains showed higher PUFA content, particularly alpha-linolenic acid, under low nutrient conditions.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Kin Sum Leung, Jean-Marie Galano, Camille Oger, Thierry Durand, Jetty Chung-Yung Lee
Summary: The study found that diets enriched with ALA have cardioprotective effects against myocardial infarction and can reduce the risk of cardiovascular disease. These diets regulate anti-inflammatory and antioxidative mediators, reducing gene expressions of inflammatory cytokines.
FREE RADICAL BIOLOGY AND MEDICINE
(2021)
Article
Agriculture, Dairy & Animal Science
Guoxin Huang, Jie Wang, Kaizhen Liu, Fengen Wang, Nan Zheng, Shengguo Zhao, Xueyin Qu, Jing Yu, Yangdong Zhang, Jiaqi Wang
Summary: The objective of this study was to determine the effect of whole flaxseed and ground flaxseed supplementation on the composition of fatty acids in plasma and milk, particularly the content of omega-3 polyunsaturated fatty acids (n-3 PUFAs). Compared with the CK group, the contents of alpha-linolenic acid (ALA), eicosatrienoic acid, and eicosapentaenoic acid increased in the plasma and milk of the WF and GF groups, and the content of docosahexaenoic acid and total n-3 PUFA was higher in the GF group. Flaxseed supplementation increased the activity of GSH-Px and decreased the concentration of MDA in milk. The result indicated that GF supplementation showed higher efficiency in increasing the total n-3 PUFA levels and the milk ALA/ALA intake ratio, and decreased the ratio of n-6 PUFAs to n-3 PUFAs in milk compared with the WF group.
