Article
Endocrinology & Metabolism
Kathryn M. Spitler, Shwetha K. Shetty, Emily M. Cushing, Kelli L. Sylvers-Davie, Brandon S. J. Davies
Summary: Hepatocyte-specific loss of ANGPTL4 does not improve triglyceride phenotypes during high-fat feeding, but these mice show improved glucose tolerance after chronic high-fat diet. Additionally, Angptl4(LivKO) mice have decreased fasting plasma triglyceride levels after an 18-h fast, but not after a 6-h fast.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
(2021)
Article
Biochemistry & Molecular Biology
Liyan Yu, Hongguang Liu, Xiaoxia Ma, Vidya Devanathadesikan Seshadri, Xuan Gao
Summary: The study found that Myrtenal has anti-atherosclerotic activity in high-fat diet-induced atherosclerosis rat models. Myrtenal-treated groups showed the ability to modulate the lipid metabolic pathway, reducing blood lipid levels and inflammatory cytokines.
APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Ren Zhang, Kezhong Zhang
Summary: Research on ANGPTL proteins, particularly the role of A8 expression in the liver and WAT, in TG partitioning has shown to be crucial for regulating LPL activity, which varies during fed and fasting cycles.
PROGRESS IN LIPID RESEARCH
(2022)
Article
Food Science & Technology
Hong Xu, Hang Gao, Feiyue Liu, Lingxiao Gong
Summary: This study found that red-skin extracts from lotus seeds can significantly improve obesity characteristics in high-fat-diet-fed mice by regulating lipoprotein lipase activity.
Article
Sport Sciences
Heath M. Burton, Edward F. Coyle
Summary: Reducing daily step counts to approximately 2500-5000 steps per day impairs the acute exercise-induced increase in fat oxidation and attenuation of postprandial plasma triglyceride increases in young healthy individuals. Exercise resistance seems to occur in individuals taking approximately 5000 or fewer steps per day, while 8500 steps per day protect against exercise resistance in fat metabolism. Fat metabolism appears to be more influenced by the inhibitory effects of inactivity than by the stimulating effects derived from 1 h of moderate-intensity running.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2021)
Article
Nutrition & Dietetics
Tomoki Abe
Summary: The prevalence of obesity is increasing worldwide and can cause various diseases. Consumption of medium-chain triglycerides can reduce body fat and insulin resistance. This study aimed to determine the timing of consumption and its effects on obesity and metabolic dysfunction induced by a high-fat high-sucrose diet.
Article
Nutrition & Dietetics
Stephanie Estafanos, Beata Friesen, Alexa Govette, Jenna B. Gillen
Summary: This study found that carbohydrate-energy replacement after low-volume high-intensity interval exercise (HIIE) can attenuate glycemic control the day following exercise in women, particularly by reducing postprandial glycemia after breakfast and snacks.
FRONTIERS IN NUTRITION
(2022)
Article
Nutrition & Dietetics
Camila L. P. Oliveira, Normand G. Boule, Aloys Berg, Arya M. Sharma, Sarah A. Elliott, Mario Siervo, Sunita Ghosh, Carla M. Prado
Summary: The study compared the impact of a high-protein meal replacement (HP-MR) versus a control (CON) breakfast on exercise metabolism. HP-MR resulted in higher fat oxidation, lower carbohydrate oxidation during exercise, reduced hunger sensation, and more favorable changes in metabolic blood markers compared to CON breakfast. The primary findings suggest that HP-MR may be beneficial for exercise performance and metabolic health.
Article
Cardiac & Cardiovascular Systems
Tatjana Josefs, Debapriya Basu, Tomas Vaisar, Britt Arets, Jenny E. Kanter, Lesley-Ann Huggins, Yunying Hu, Jianhua Liu, Noemie Clouet-Foraison, Jay W. Heinecke, Karin E. Bornfeldt, Ira J. Goldberg, Edward A. Fisher
Summary: The study found that hypertriglyceridemia and reduced HDL-C did not affect atherosclerosis lesion size or macrophage content, suggesting that atherosclerosis regression in mice is primarily driven by LDL-C reduction and not impacted by hypertriglyceridemia and plasma HDL-C levels.
CIRCULATION RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Marcos Yukio Yoshinaga, Bruna Jardim Quintanilha, Adriano Britto Chaves-Filho, Sayuri Miyamoto, Geni Rodrigues Sampaio, Marcelo Macedo Rogero
Summary: Postprandial lipemia can lead to changes in plasma lipid composition and differential responses in individuals, influencing HDL functions. Comprehensive characterization of plasma lipidome responses to acute metabolic challenges can enhance understanding of lipid and glucose metabolism regulation through diet/lifestyle interventions.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2021)
Article
Nutrition & Dietetics
Zhizheng Fang, Lu Wei, Yanping Lv, Tongsheng Wang, Hamizah Shahirah Hamezah, Rongchun Han, Xiaohui Tong
Summary: This study investigates the impact of Phillyrin on obesity-related metabolic dysfunctions. It was found that Phillyrin reduces circulating level of glycerol, hepatic steatosis, and improves insulin sensitivity in obese mice. Phillyrin also attenuates obesity-related inflammation and IL-6 production in adipose tissue. Furthermore, Phillyrin inhibits IL-6-initiated basal lipolysis and expression of adipose triglyceride lipase (ATGL) in adipose tissue. These findings suggest that Phillyrin can be a potential candidate in the treatment of obesity-associated complications.
FRONTIERS IN NUTRITION
(2022)
Article
Multidisciplinary Sciences
Ismael Valladolid-Acebes, Karin Avall, Patricia Recio-Lopez, Noah Moruzzi, Galyna Bryzgalova, Marie Bjornholm, Anna Krook, Elena Fauste Alonso, Madelene Ericsson, Fredrik Landfors, Stefan K. Nilsson, Per-Olof Berggren, Lisa Juntti-Berggren
Summary: Lowering apoCIII can protect against and reverse the metabolic phenotype induced by HFD by promoting physiological insulin sensitivity.
Review
Cardiac & Cardiovascular Systems
Ira J. Goldberg, Ainara G. Cabodevilla, Dmitri Samovski, Vincenza Cifarelli, Debapriya Basu, Nada A. Abumrad
Summary: Lipoprotein lipase mediates the transfer of lipids to parenchymal cells through or around endothelial cells, controlled at multiple points from synthesis to inhibition. Various pathways, including fatty acid transporter CD36 and other receptors, facilitate the transit of lipids into muscle and adipose tissues. Endothelial cells play a crucial role in lipid delivery, but there are still aspects of this process that require further investigation.
Article
Nutrition & Dietetics
Takumi Nagasawa, Takao Kimura, Akihiro Yoshida, Katsuhiko Tsunekawa, Osamu Araki, Kazumi Ushiki, Hirotaka Ishigaki, Yoshifumi Shoho, Itsumi Suda, Suguru Hiramoto, Masami Murakami
Summary: The study demonstrated that supplementing rice gruel with KGM powder led to reductions in circulating levels of free fatty acids and triglycerides, while increasing lipoprotein lipase and GPIHBP1 levels. This indicates a novel pleiotropic effect of KGM on lipid metabolism.
Article
Nutrition & Dietetics
Chaise Murphy, Laura D. Bilek, Karsten Koehler
Summary: The study suggests that low energy availability (LEA) may negatively impact bone health, with high-protein diets not attenuating these effects. LEA appears to shift bone turnover in favor of bone resorption.
Article
Physiology
Eric C. Freese, Nicholas H. Gist, Rachelle M. Acitelli, Whitni J. McConnell, Catherine D. Beck, Dorothy B. Hausman, Jonathan R. Murrow, Kirk J. Cureton, Ellen M. Evans
JOURNAL OF APPLIED PHYSIOLOGY
(2015)
Article
Medicine, General & Internal
Nicholas H. Gist, Eric C. Freese, Terence E. Ryan, Kirk J. Cureton
Article
Public, Environmental & Occupational Health
Weimo Zhu, Matthew T. Mahar, Gregory J. Welk, Scott B. Going, Kirk J. Cureton
AMERICAN JOURNAL OF PREVENTIVE MEDICINE
(2011)
Article
Public, Environmental & Occupational Health
Gregory J. Welk, Kelly R. Laurson, Joey C. Eisenmann, Kirk J. Cureton
AMERICAN JOURNAL OF PREVENTIVE MEDICINE
(2011)
Article
Public, Environmental & Occupational Health
Jonathan E. Wingo, Laura J. Salaga, Mia K. Newlin, Kirk J. Cureton
AVIATION SPACE AND ENVIRONMENTAL MEDICINE
(2012)
Article
Physiology
Jennifer L. Trilk, Arpit Singhal, Kevin A. Bigelman, Kirk J. Cureton
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
(2011)
Review
Physiology
Jonathan E. Wingo, Matthew S. Ganio, Kirk J. Cureton
EXERCISE AND SPORT SCIENCES REVIEWS
(2012)
Article
Nutrition & Dietetics
Patrick J. O'Connor, Amanda L. Caravalho, Eric C. Freese, Kirk J. Cureton
INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM
(2013)
Review
Physiology
Eric C. Freese, Nicholas H. Gist, Kirk J. Cureton
JOURNAL OF APPLIED PHYSIOLOGY
(2014)
Article
Hospitality, Leisure, Sport & Tourism
Eric C. Freese, Rachelle M. Acitelli, Nicholas H. Gist, Kirk J. Cureton, Ellen M. Evans, Patrick J. O'Connor
JOURNAL OF SPORT & EXERCISE PSYCHOLOGY
(2014)
Article
Sport Sciences
Eric C. Freese, Nicholas H. Gist, Kirk J. Cureton
JOURNAL OF STRENGTH AND CONDITIONING RESEARCH
(2013)
Article
Sport Sciences
Nicholas H. Gist, Eric C. Freese, Kirk J. Cureton
JOURNAL OF STRENGTH AND CONDITIONING RESEARCH
(2014)
Article
Hospitality, Leisure, Sport & Tourism
Kirk J. Cureton, Matthew T. Mahar
RESEARCH QUARTERLY FOR EXERCISE AND SPORT
(2014)
Review
Sport Sciences
Nicholas H. Gist, Michael V. Fedewa, Rod K. Dishman, Kirk J. Cureton