A naturally occurring variant of the human prion protein completely prevents prion disease

Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

(2013) Mathias Jucker et al.   NATURE

Dominant prion mutants induce curing through pathways that promote chaperone-mediated disaggregation

(2011) Susanne DiSalvo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Strain Specific Resistance to Murine Scrapie Associated with a Naturally Occurring Human Prion Protein Polymorphism at Residue 171

(2011) James F. Striebel et al.   PLoS Pathogens

Review: Contribution of transgenic models to understanding human prion disease

(2010) J. D. F. Wadsworth et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Absence of spontaneous disease and comparative prion susceptibility of transgenic mice expressing mutant human prion proteins

(2009) E. A. Asante et al.   JOURNAL OF GENERAL VIROLOGY

A Novel Protective Prion Protein Variant that Colocalizes with Kuru Exposure

(2009) Simon Mead et al.   NEW ENGLAND JOURNAL OF MEDICINE

Crystal structure of human prion protein bound to a therapeutic antibody

(2009) S. V. Antonyuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Prion Protein (PrP) 219K Is Converted to PrPScbut Shows Heterozygous Inhibition in Variant Creutzfeldt-Jakob Disease Infection

(2008) Masaki Hizume et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The epidemiology of kuru: monitoring the epidemic from its peak to its end

(2008) M. P. Alpers   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Kuru prions and sporadic Creutzfeldt-Jakob disease prions have equivalent transmission properties in transgenic and wild-type mice

(2008) J. D. F. Wadsworth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA